Perfectionism,Stress, Daily Hassles,Hopelessness, and Suicide Potential in Depressed Psychiatric Adolescents

The current study examined dimensions of perfectionism, stress, hopelessness, and suicidality in a sample of adolescent psychiatric patients diagnosed with depression. This study evaluated the unique contribution of perfectionism in predicting suicidality after considering other predictors (i.e., hopelessness, depression) and it also examined the diathesis-stress model of perfectionism and suicide. A sample of 55 adolescents (41 females, mean age = 15.53, 25.5 % ethnic/racial minorities) who were psychiatric patients completed measures including the Child-Adolescent Perfectionism Scale, subjective and objective indices of life stress, daily hassles, depression, hopelessness, suicide ideation, prior attempts and suicide potential. In addition, other informants (i.e., adolescents’ parents) completed a diagnostic interview and an interview assessing major stressful experiences. Socially prescribed perfectionism (i.e., the perception that others require perfection of oneself) predicted concurrent levels of suicide potential and this association with suicide potential held even after controlling for the variances accounted for by depression and hopelessness. Hierarchical regression analyses provided partial support for the diathesis-stress model, that is, socially prescribed perfectionism interacted with daily hassles to predict concurrent suicide potential even after controlling for depression, hopelessness, and prior suicide attempt. Together, these findings suggest that socially prescribed perfectionism acts as a vulnerability factor that is predictive of suicide potential or risk among clinically depressed adolescents.     

EGFR突变NSCLC二线TKIs治疗优化选择

恶性肿瘤的治疗已经进入驱动基因指导下的个体治疗时代,肺癌患者应该进行多基因检测,特别是表皮生长因子受体（EGFR）基因突变。EGFR基因突变的非小细胞肺癌（NSCLC）患者,如果一线接受了化疗,二线应该选择表皮生长因子受体一酪氨酸酶抑制剂（EGFR—TKIs）。EGFR基因突变的NSCLC患者一线EGFR—TKIs治疗失败后,二线治疗应该是个体化合理选择,包括局部放疗、化疗和继续EGFR—TKIs。目前一代和二代EGFR—TKIs药物之间未见到显著疗效差别。第三代EGFR—TKIs是目前的EGFR—TKIs耐药后的最有希望的选择,特别是针对T790M突变耐药。     

CAT选题策略分类概述

选题是计算机化自适应测验（CAT）测试过程的关键环节,选题策略的目标是要达到较高的测量精度,同时也实现试题曝光率控制及其他测验目标的实现.本文根据选题策略的基本原理和衍生发展,将众多CAT选题策略分为五大选题策略系列：Fisher函数系列、K-LI函数系列、α分层系列、贝叶斯系列、b匹配系列;并根据测验目标（测验精度、试题曝光率控制、内容平衡、多条件约束）对这些选题策略进行了细分,并对CAT选题策略的选择思路进行归纳.     

Around the world,adolescence is a time of heightened sensation seeking and immature self‐regulation

The dual systems model of adolescent risk‐taking portrays the period as one characterized by a combination of heightened sensation seeking and still‐maturing self‐regulation, but most tests of this model have been conducted in the United States or Western Europe. In the present study, these propositions are tested in an international sample of more than 5000 individuals between ages 10 and 30 years from 11 countries in Africa, Asia, Europe and the Americas, using a multi‐method test battery that includes both self‐report and performance‐based measures of both constructs. Consistent with the dual systems model, sensation seeking increased between preadolescence and late adolescence, peaked at age 19, and declined thereafter, whereas self‐regulation increased steadily from preadolescence into young adulthood, reaching a plateau between ages 23 and 26. Although there were some variations in the magnitude of the observed age trends, the developmental patterns were largely similar across countries.     

Auditory‐motor adaptation is reduced in adults who stutter but not in children who stutter

Previous studies have shown that adults who stutter produce smaller corrective motor responses to compensate for unexpected auditory perturbations in comparison to adults who do not stutter, suggesting that stuttering may be associated with deficits in integration of auditory feedback for online speech monitoring. In this study, we examined whether stuttering is also associated with deficiencies in integrating and using discrepancies between expected and received auditory feedback to adaptively update motor programs for accurate speech production. Using a sensorimotor adaptation paradigm, we measured adaptive speech responses to auditory formant frequency perturbations in adults and children who stutter and their matched nonstuttering controls. We found that the magnitude of the speech adaptive response for children who stutter did not differ from that of fluent children. However, the adaptation magnitude of adults who stutter in response to auditory perturbation was significantly smaller than the adaptation magnitude of adults who do not stutter. Together these results indicate that stuttering is associated with deficits in integrating discrepancies between predicted and received auditory feedback to calibrate the speech production system in adults but not children. This auditory‐motor integration deficit thus appears to be a compensatory effect that develops over years of stuttering.     

Systems Factorial Technology provides new insights on the other-race effect

The other-race effect refers to the difficulty of discriminating between faces from ethnic and racial groups other than one’s own. This effect may be caused by a slow, feature-by-feature, analytic process, whereas the discrimination of own-race faces occurs faster and more holistically. However, this distinction has received inconsistent support. To provide a critical test, we employed Systems Factorial Technology (Townsend & Nozawa in Journal of Mathematical Psychology, 39, 321–359, 1995), which is a powerful tool for analyzing the organization of mental networks underlying perceptual processes. We compared Taiwanese participants’ face discriminations of both own-race (Taiwanese woman) and other-race (Caucasian woman) faces according to the faces’ nose-to-mouth separation and eye-to-eye separation. We found evidence for weak holistic processing (parallel processing) coupled with the strong analytic property of a self-terminating stopping rule for own-race faces, in contrast to strong analytic processing (serial self-terminating processing) for other-race faces, supporting the holistic/analytic hypothesis.     

亲子关系对贫困儿童问题行为的影响

以247名贫困儿童为被试进行问卷调查,构建家庭社会经济地位和亲子关系对贫困儿童问题行为的多重中介模型,得到抑郁、自我控制的中介作用。结果显示,亲子关系和社会经济地位分别通过中介路径影响贫困儿童问题行为,与亲子关系有关的中介路径为91.25%,与抑郁有关的中介效应为57.60%,与自我控制有关的中介效应为57.15%. 结论：良好的亲子关系或成为贫困儿童的保护因子;应关注贫困儿童心理健康,增加有效心理疏导机制;注重培养贫困儿童的自我控制能力。     

Discrimination threshold for haptic volume perception of fingers and phalanges

Humans exhibit a remarkable ability to discriminate variations in object volume based on natural haptic perception. The discrimination thresholds for the haptic volume perception of the whole hand are well known, but the discrimination thresholds for haptic volume perception of fingers and phalanges are still unknown. In the present study, two psychophysical experiments were performed to investigate haptic volume perception in various fingers and phalanges. The configurations of both experiments were completely dependent on haptic volume perception from the fingers and phalanges. The participants were asked to blindly discriminate the volume variation of regular solid objects in a random order by using the distal phalanx, medial phalanx, and proximal phalanx of their index finger, middle finger, ring finger, and little finger. The discrimination threshold of haptic volume perception gradually decreases from the little finger to the index finger as well as from the proximal phalanx to the distal phalanx. Overall, both the shape of the target and the part of the finger in contact with the target significantly influence the precision of haptic perception of volume. This substantial data set provides detailed and compelling perspectives on the haptic system, including for discrimination of the spatial size of objects and for performing more general perceptual processes.     

Perceptual experience shapes our ability to categorize faces by national origin: A new other-race effect

People are better at recognizing own-race than other-race faces. This other-race effect has been argued to be the result of perceptual expertise, whereby face-specific perceptual mechanisms are tuned through experience. We designed new tasks to determine whether other-race effects extend to categorizing faces by national origin. We began by selecting sets of face stimuli for these tasks that are typical in appearance for each of six nations (three Caucasian, three Asian) according to people from those nations (Study 1). Caucasian and Asian participants then categorized these faces by national origin (Study 2). Own-race faces were categorized more accurately than other-race faces. In contrast, Asian American participants, with more extensive other-race experience than the first Asian group, categorized other-race faces better than own-race faces, demonstrating a reversal of the other-race effect. Therefore, other-race effects extend to the ability to categorize faces by national origin, but only if participants have greater perceptual experience with own-race, than other-race faces. Study 3 ruled out non-perceptual accounts by showing that Caucasian and Asian faces were sorted more accurately by own-race than other-race participants, even in a sorting task without any explicit labelling required. Together, our results demonstrate a new other-race effect in sensitivity to national origin of faces that is linked to perceptual expertise.