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931.
932.
933.
The present work investigated the impact of affect in landmark-based wayfinding. We assumed that affect-laden landmarks improve wayfinding performance and have an impact on later landmark recognition. To investigate our hypotheses, we ran two experiments in a virtual maze. In Experiment 1, we investigated how affect-laden landmarks influence wayfinding and recognition in comparison with neutral landmarks. The aim of Experiment 2 was to focus on the affective valence of a landmark. The memory tasks of both experiments were repeated after 1 week in order to assess memory consolidation. Results showed that the best wayfinding and recognition performance occurs when negatively laden landmarks were used. In comparison with neutral and positively laden landmarks, recognition performance hardly decreased over time for the negatively laden landmarks. Our results not only support findings in the field of emotion research but also expand the concept of semantic landmark salience with respect to emotional responses.  相似文献   
934.

Background

Despite five decades of increasingly elegant studies aimed at advancing the pathophysiology and treatment of mental illness, the results have not met expectations. Diagnoses are still based on observation, the clinical history, and an outmoded diagnostic system that stresses the historic goal of disease specificity. Psychotropic drugs are still based on molecular targets developed decades ago, with no increase in efficacy. Numerous biomarkers have been proposed, but none have the requisite degree of sensitivity and specificity, and therefore have no usefulness in the clinic. The obvious lack of progress in psychiatry needs exploration.

Methods

The historical goals of psychiatry are reviewed, including parity with medicine, a focus on diagnostic reliability rather than validity, and an emphasis on reductionism at the expense of socioeconomic issues. Data are used from Thomas Picketty and others to argue that our failure to advance clinical care may rest in part on the rise in social and economic inequality that began in the 1970s, and in part on our inability to move beyond the medical model of specificity of disease and treatment.

Results

It is demonstrated herein that the historical goal of specificity of disease and treatment has not only impeded the advance of diagnosis and treatment of mental illness, but, in combination with a rapid increase in socioeconomic inequality, has led to poorer outcomes and rising mortality rates in a number of disorders, including schizophrenia, anxiety, and depression.

Conclusions

It is proposed that Psychiatry should recognize the fact of socioeconomic inequality and its effects on mental disorders. The medical model, with its emphasis on diagnostic and treatment specificity, may not be appropriate for investigation of the brain, given its complexity. The rise of scientific inequality, with billions allocated to connectomics and genetics, may shift attention away from the need for improvements in clinical care. Unfortunately, the future prospects of those suffering from mental illness appear dim.
  相似文献   
935.

Background

Medical tourism, the practice of persons intentionally travelling across international boundaries to access medical care, has drawn increasing attention from researchers, particularly in relation to potential ethical concerns of this practice. Researchers have expressed concern for potential negative impacts to individual safety, public health within both countries of origin for medical tourists and destination countries, and global health equity. However, these ethical concerns are not discussed within the sources of information commonly provided to medical tourists, and as such, medical tourists may not be aware of these concerns when engaging in medical tourism. This paper describes the methodology utilized to develop an information sheet intended to be disseminated to Canadian medical tourists to encourage contemplation and further public discussion of the ethical concerns in medical tourism.

Methods

The methodology for developing the information sheet drew on an iterative process to consider stakeholder feedback on the content and use of the information sheet as it might inform prospective medical tourists’ decision making. This methodology includes a literature review as well as formative research with Canadian public health professionals and former medical tourists.

Results

The final information sheet underwent numerous revisions throughout the formative research process according to feedback from medical tourism stakeholders. These revisions focused primarily on making the information sheet concise with points that encourage individuals considering travelling for medical tourism to do further research regarding their safety both within the destination country, while travelling, and once returning to Canada, and the potential impacts of their trip on third parties. This methodology may be replicated for the development of information sheets intending to communicate ethical concerns of other practices to providers or consumers of a certain service.
  相似文献   
936.
Much of the fear and uncertainty around Zika epidemics stem from potential association between Zika virus (ZIKV) complications on infected pregnant women and risk of their babies being born with microcephaly and other neurological abnormalities. However, much remains unknown about its mode of transmission, diagnosis and long-term pathogenesis. Worries of these unknowns necessitate the need for effective and efficient psychosocial programs and medical-legal strategies to alleviate and mitigate ZIKV related burdens. In this light, local and global efforts in maintaining fundamental health principles of moral, medical and legal decision-making policies, and interventions to preserve and promote individual and collectiveHuman Rights, autonomy, protection of the most vulnerable, equity, dignity, integrity and beneficence that should not be confused and relegated by compassionate humanitarian assistance and support. This paper explores the potential medical and ethical-legal implications of ZIKV epidemics emergency response packages and strategies alongside optimizing reproductive and mental health policies, programs and best practice measures. Further long-term cross-borders operational research is required in elucidating Zika-related population-based epidemiology, ethical-medical and societal implications in guiding evidence-based local and global ZIKV maternal-child health complications related approaches and interventions. Core programs and interventions including future Zika safe and effective vaccines for global Zika immunization program in most vulnerable and affected countries and worldwide should be prioritized.  相似文献   
937.
Stroop effects can be modulated by context-specific cues associated with different levels of proportion congruent, even for items that appear equally frequently in each context. This result has important theoretical implications, because it rules out frequency-driven learning explanations of context-specific proportion congruent (CSPC) effects and leaves open the possibility that a cue-driven retrieval process can reinstate attentional control settings in a rapid online fashion. The purpose of the present work was to address reproducibility concerns that have been raised about this finding. We conducted several reproductions and novel extensions using Amazon’s mechanical Turk in both Stroop and flanker tasks. We successfully replicated the central finding that CSPC effects can be observed for frequency-unbiased items. We also provide new Monte Carlo simulation analyses to estimate reproducibility of the phenomena that show important limitations on these designs for measuring contextual control.  相似文献   
938.
Much previous research has examined various aspects of auditory processing, including the localization of sounds, and the influence of lexical and indexical information on language processing. In the present set of experiments we explored the ability of listeners to estimate the number of speakers in a group solely from the information in an auditory signal. The bound on accurately estimating the number of simultaneous speakers is 3. We suggest that subitization—the ability to estimate numerosity of visual and auditory elements without explicitly counting these elements—rather than the capacity of short-term memory, may underlie this limitation. The cognitive constraint on estimating the number of simultaneous speakers may have implications for a wide variety of seemingly unrelated psychological phenomena.  相似文献   
939.
This paper aims to put forward the foundation for building a theory of meaning-making based on emptiness. The theoretical perspective underlying the discussion is the cultural psychology of semiotic mediation. According to this perspective, meaning-making is the result of the process through witch human beings use signs to build their relationship with their environment. Three topics unfold in the paper. First, emptiness is defined as a potential absence. Second, the paper identifies the two ways in which emptiness enters into the meaning-making process, either fostering it or, to the contrary, blocking it. When it fosters meaning construction, emptiness acts as a catalytic factor, that is, as a reservoir of possibilities, in the sense of a future-oriented set of new meanings to be built by the agent. However, when emptiness plays the role of a blocking or anti-catalytic factor, emptiness become a hyper-generalized sign, i.e., an empty meaning. Third, this paper illustrates the applicability of these theoretical reflections on emptiness through the example of work. Specifically, both the burnout and the so-called “placardisation” phenomena are analyzed in terms of the anti-catalytic factors at play in work, which lead to feeling it as empty.  相似文献   
940.
Noninvasive brain stimulation methods are becoming increasingly common tools in the kit of the cognitive scientist. In particular, transcranial direct-current stimulation (tDCS) is showing great promise as a tool to causally manipulate the brain and understand how information is processed. The popularity of this method of brain stimulation is based on the fact that it is safe, inexpensive, its effects are long lasting, and you can increase the likelihood that neurons will fire near one electrode and decrease the likelihood that neurons will fire near another. However, this method of manipulating the brain to draw causal inferences is not without complication. Because tDCS methods continue to be refined and are not yet standardized, there are reports in the literature that show some striking inconsistencies. Primary among the complications of the technique is that the tDCS method uses two or more electrodes to pass current and all of these electrodes will have effects on the tissue underneath them. In this tutorial, we will share what we have learned about using tDCS to manipulate how the brain perceives, attends, remembers, and responds to information from our environment. Our goal is to provide a starting point for new users of tDCS and spur discussion of the standardization of methods to enhance replicability.  相似文献   
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