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71.
72.
Celia Goeldner Davids Reiss Jürgen Wichmann Brigitte L. Kieffer Abdel-Mouttalib Ouagazzal 《Neurobiology of learning and memory》2009,91(4):393-401
The present study investigated whether the selective nociceptin opioid peptide (NOP) receptor agonist, Ro64-6198, impairs acquisition of fear conditioning through glutamatergic mechanisms. Systemic administration of Ro64-6198 (0.3 and 1 mg/kg) or the non-competitive NMDA receptor antagonist, MK-801 (0.03 and 0.1 mg/kg) prior to conditioning severely impaired contextual but not cued fear learning in C57BL/6N mice. When administered together at sub-effective doses, Ro64-6198 (0.5 mg/kg) and MK-801 (0.05 mg/kg), synergistically impaired contextual fear learning, but left cued fear learning intact. We next used the immediate shock deficit paradigm (ISD) to examine the effects of Ro64-6198 and MK-801 on contextual memory formation in the absence of the foot-shock. As expected, naive mice that were shocked briefly after being placed in the training chamber displayed no contextual fear conditioning. This learning deficit was elevated by prior exposure of mice to the training context. Furthermore, administration of Ro64-6198 and MK-801, either separately at amnesic doses (1 mg/kg and 0.1 mg/kg, respectively) or concomitantly at sub-effective doses (0.5 mg/kg and 0.05 mg/kg, respectively) significantly reduced the facilitating effects of context preexposure. These findings demonstrate the existence of functional antagonism between NOP and NMDA receptors that predominantly contributes to modulation of conditioned fear learning which involves spatial-processing demands. 相似文献
73.
The aim of this study was to examine salivary cortisol and testosterone concentrations in professional male athletes during a short triathlon competition using non-invasive methods, and to determine whether these hormone concentrations could be accurate predictors of performance. Eight adult male athletes (age, mean ± SEM: 27.8 ± 3.2 years; body mass index: 21.66 ± 0.42) in a professional triathlon team volunteered to participate in this study. Saliva samples were taken on the competition day and 7 days after competition on a rest day. The performance of the athletes was assessed by their rank order in the competition. Salivary cortisol concentrations were greater on the competition day than on the rest day in the early morning, immediately after waking up, 30 min later, immediately before the start of the competition, and later in the evening. Testosterone concentrations were greater on the competition day in the morning and in the evening. The diurnal rhythm of both cortisol and testosterone concentrations was maintained on both days and the testosterone/cortisol ratio (T/C ratio) was similar between days. The performance of the athletes was positively correlated with salivary cortisol concentration in the early morning of the competition day, but was not correlated with testosterone concentrations at any of the time points. In conclusion, early morning salivary cortisol concentration, but not T/C ratio, could be used to predict performance in athletes during a professional triathlon competition. 相似文献
74.
Andrade FC Raffaelli M Teran-Garcia M Jerman JA Garcia CA;Up Amigos Study Group 《Body image》2012,9(1):184-188
Individuals who misperceive their body size are at risk for eating disorders, unhealthy weight control practices, and obesity-related diseases. This study assessed the prevalence and demographic, behavioral, and psychosocial correlates of agreement between perceived (self-reported) and actual (measured) body mass index categories in a sample of Mexican college applicants aged 18-20 years (N=3622; 52% female). Under two thirds (63.1%) accurately reported their weight status categories. Reporting accuracy was lower among overweight and obese participants. In multivariate analyses, overestimating was associated with female gender, younger age, lower level of parent education, and more hours of daily TV viewing; underestimating was associated with male gender and older age. In within-gender analyses, overestimating was associated with hours of TV among men and underestimating was positively associated with depressive symptoms among women. This study adds to a growing international literature on body weight status misperception among adolescents and young adults. 相似文献
75.
Yeon-Shim Lee Celia P. Kaplan Eliseo J. Perez-Stable 《Journal of aggression, maltreatment & trauma》2014,23(1):20-44
The purpose of this study was to identify dimensions of elder mistreatment in Chinese and Korean immigrant communities and to increase sociocultural understanding of such mistreatment by elucidating the complexities of abuse embedded in unique social and cultural contexts. In-depth interviews were conducted with 20 local professionals working primarily in Asian elderly advocacy, and six focus group discussions were conducted involving 60 community members in the San Francisco Bay area. Five dimensions of elder mistreatment were identified: psychological abuse, neglect by a trusted person, financial exploitation, physical abuse, and sexual abuse. In general, fewer Korean community member participants reported having observed physical or financial abuse than Chinese groups, but they reported greater knowledge of situations involving psychological abuse, neglect by a trusted person, and sexual abuse. The contexts of cultural influences and immigration and acculturation were salient themes that shaped participants’ subjective perceptions and beliefs about elder abuse and hence help-seeking behaviors. 相似文献
76.
Recent research in cognitive psychology has emphasised the uses, or functions, of autobiographical memory. Theoretical and empirical approaches have focused on a three-function model: autobiographical memory serves self, directive, and social functions. In the reminiscence literature other taxonomies and additional functions have been postulated. We examined the relationships between functions proposed by these literatures, in order to broaden conceptualisations and make links between research traditions. In Study 1 we combined two measures of individual differences in the uses of autobiographical memory. Our results suggested four classes of memory functions, which we labelled Reflective, Generative, Ruminative, and Social. In Study 2 we tested relationships between our four functions and broader individual differences, and found conceptually consistent relationships. In Study 3 we found that memories cued by Generative and Social functions were more emotionally positive than were memories cued by Reflective and Ruminative functions. In Study 4 we found that reported use of Generative functions increased across the lifespan, while reported use of the other three functions decreased. Overall our findings suggest a broader view of autobiographical memory functions that links them to ways in which people make meaning of their selves, their environment, and their social world more generally. 相似文献
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78.
Little is known about the mechanisms by which psychology graduate programs transmit responsible conduct of research (RCR) values. A national sample of 968 current students and recent graduates of mission-diverse doctoral psychology programs completed a Web-based survey on their research ethics challenges, perceptions of RCR mentoring and department climate, whether they were prepared to conduct research responsibly, and whether they believed psychology as a discipline promotes scientific integrity. Research experience, mentor RCR instruction and modeling, and department RCR policies predicted student RCR preparedness. Mentor RCR instruction, department RCR policies, and faculty modeling of RCR behaviors predicted confidence in the RCR integrity of the discipline. Implications for training are discussed. 相似文献
79.
80.
Celia Fix Korbivcher 《The International journal of psycho-analysis》2013,94(4):645-665
This article examines the implications of the proposal of autistic transformations within the general context of Bion's theory of Transformations. The aim is to confirm the coherence of this proposal of autistic transformations within the overall structure of Bion's theory of Transformations. She examines the relation between emotional links and their negatives, particularly –K. She questions in which of the dimensions of the mind the autistic phenomena are located, the relation between autistic phenomena and beta elements, and where to place them in the Grid. The author tries to form metapsychological support for the incorporation of the autistic area in Bion's theory of Transformations. She argues that, despite the incongruence and imprecision of this incorporation, such autistic phenomena cannot be excluded from the complexus of the human mind and should therefore be accounted for in Bion's t ransformations . She discusses the idea that the theory of transformations includes the field of the neurosis and psychosis and deals with emotions, whereas the autistic area is dominated by sensations. The author asks how to add the autistic area to Bion's theory. Clinical material of a child for whom the non‐psychotic part of the personality predominates and who presents autistic nuclei provides material for the discussion. 相似文献