Inhibition of Return in children with Tourette's syndrome and comorbid forms: A Preliminary Study

Background: This study investigated the nature and functioning of the visual-spatial inhibition of return (IOR) phenomenon in children with “pure” Tourette's syndrome (TS), and those with comorbid forms of TS. Method: Children with TS-only and “TS + comorbid” (TS + ADHD +/- OCD) and matched controls performed the inhibition of return (IOR) task, which involved responding to left and right visual targets appearing on a computer screen that were preceded by congruent or incongruent exogenous visual cues. Results: The TS-only group performed similarly on the IOR task to the controls. When the TS-only group was subdivided into children with mild and severe TS symptoms, a post hoc comparison between the controls and severe TS symptom children revealed that these TS children had a reduced magnitude of IOR for targets appearing in the right visual field. The comparison between the TS + comorbid and controls revealed an atypical IOR pattern for the TS + comorbid group. They displayed a loss of normal facilitatory and inhibitory effects for right visual field targets. Conclusions: The findings suggest abnormalities in attentional “disengage” and “move” mechanisms in TS when directing attention to the right visual field, which may reflect left posterior parietal, superior colliculus, and midbrain pathology.     

Understanding and Integrating Multiple Science Texts: Summary Tasks are Sometimes Better Than Argument Tasks

One of the major challenges of a knowledge society is that students as well as other citizens must learn to understand and integrate information from multiple textual sources. Still, task and reader characteristics that may facilitate or constrain such intertextual processes are not well understood by researchers. In this study, we compare the effects of summary and argument essay tasks when undergraduates read seven different texts on a particular scientific topic, finding that an instruction to write summaries may lead to better understanding and integration than an instruction to write argument essays. We discuss several possible explanations for this result. We also found that beliefs about the certainty of knowledge in some instances can moderate the effect of task on comprehension performance.     

Motivated Closed‐Mindedness Mediates the Effect of Threat on Political Conservatism

In this article we synthesize theory and research from several areas of psychology and political science to propose and test a causal model of the effects of threat on political attitudes. Based in part on prior research showing that fear, threat, and anxiety decrease cognitive capacity and motivation, we hypothesize that under high (vs. low) threat, people will seek to curtail open‐ended information searches and exhibit motivated closed‐mindedness (one aspect of the need for cognitive closure). The subjective desire for certainty, control, and closure, in turn, is expected to increase the individual's affinity for political conservatism, insofar as resistance to change and adherence to authority figures and conventional forms of morality are assumed to satisfy these epistemic motives more successfully than their ideological opposites. Consistent with this account, we find in Studies 1a and 1b that putting people into a highly threatened mindset leads them to exhibit an increase in motivated closed‐mindedness and to perceive the world as more dangerous. Furthermore, in Study 2 we demonstrate that a subtle threat manipulation increases self‐reported conservatism (or decreases self‐reported liberalism), and this effect is mediated by closed‐mindedness. In Study 3, we manipulated closed‐mindedness directly and found that high (vs. low) cognitive load results in a greater affinity for the Republican (vs. Democratic) party. Finally, in Study 4 we conducted an experiment involving political elites in Iceland and found that three different types of threat (to the self, group, and system) all led center‐right politicians to score higher on closed‐mindedness and issue‐based political conservatism. Implications for society and for the theory of ideology as motivated social cognition are discussed.     

Visual information and rubber hand embodiment differentially affect reach-to-grasp actions

During the “rubber hand illusion” (RHI) participants feel touch originating from an artificial hand, which is felt to belong to the own body. The perceived location of the real hand is shifted towards the location of the artificial hand. However, evidence as to whether the RHI is accompanied by alterations of hand action is mixed. We found that the perceived size of one's own hand was affected by the size of the artificial hand that was used to elicit the illusion. Moreover, we tested a possible transfer of the RHI to a reach-to-grasp action. We observed that hand transport (i.e., reach) errors after RHI induction were independent of artificial hand size, showing that the parameter which is important for these reaching errors is the hand's perceived location. Results thus show that the RHI affects not only perceptual, but also action processing. In contrast, grip aperture was affected by artificial hand size independent of the RHI, suggesting that visual information about hand size affects grasping independent of embodiment of the artificial hand. Grip size increased with artificial hand size; this effect is explained by a higher reliance on proprioceptive information during blind reaching after receiving distorted visual information.     

Parental Attitudes,Beliefs, and Perceptions about Genetic Testing for FAP and Colorectal Cancer Surveillance in Minors

Familial adenomatous polyposis (FAP) is the second most common hereditary colorectal cancer syndrome and confers a nearly 100% lifetime risk of developing colorectal cancer. Understanding factors that facilitate and inhibit genetic testing and cancer surveillance in children who are members of families affected by FAP will better equip clinicians to clarify misunderstandings and facilitate appropriate care. The aims of this study were to examine parental attitudes and beliefs regarding endoscopic surveillance and genetic testing in minors at risk for developing FAP. This cross-sectional study includes analyses of qualitative and quantitative interview data collected from parents of children with or at risk for FAP. This report includes data from 28 parents with a total of 51 biological children between 10–17 years of age. The parents had a clinical and/or genetic diagnosis of FAP. Most commonly reported facilitators included provider recommendation (surveillance) and personalized medical management (genetic testing). Most commonly reported barriers included lack of provider recommendation (surveillance) and cost (genetic testing).     

What matters in the associative learning of visual cues in foraging parasitoid wasps: colour or brightness?

Visual cues are known to be used by numerous animal taxa to gather information on quality and localisation of resources. Because environmental lighting can interfere with the spectral features of visual cues, the specific characteristics of the colour signals that promote forager decision and learning are still not known in the majority of insects (excepted in bees). We analysed the effect of previous experience on the use of visual information by the wasp Venturia canescens, a parasitoid of pyralidae, in the context of host searching. These parasitoids search for hosts concealed in several fruit species, so visual cues from the host microhabitat could play a key role in host finding. We also investigated the type of visual cues on which wasps based their decision. We tested whether wasps are able to associate an achromatic cue (brightness) or a chromatic one (hue, i.e. dominant wavelength and/or chroma) with the presence of hosts. Our results show that in the context of host foraging, chromatic cues are more reliable than brightness in achieving the associative learning process. Therefore, understanding the behavioural ecology of foraging should make use of the knowledge about the visual information used.     

Processing of compound visual stimuli by children with autism and Asperger syndrome

A typical modes of visual processing are common in individuals with autism. In particular, and unlike typically developing children, children with autism tend to process the parts of a complex object as a priority, rather than attending to the object as a whole. This bias for local processing is likely to be due to difficulties in assembling subparts into a coherent whole, as proposed by Frith ( 10 1989) using the term “weak central coherence” or WCC. This study was aimed to better characterize the processing of complex visual stimuli by children with autism. Thirteen children with autistic spectrum disorders were individually paired with children of two control groups, one matched on verbal mental age (VMA) and one matched on chronological age (CA). Participants from the three groups were tested in two tasks. The first task involved hierarchical global/local stimuli, inspired by Navon ( 30 1977). The second task employed compound face‐like or geometrical stimuli. This task emphasized the processing of configural properties of the stimuli (i.e., spatial relationships). Children from the three groups showed a perceptual bias favouring the global dimension of the stimuli in the first task. By contrast, children with autism were deficient compared to normal children for the processing of the configural dimensions of the stimuli in the second task. These results suggest that visual cognition of children with autism is characterized by a dissociation between global and configural processing, with global processing being preserved and configural processing being altered in these children, therefore delineating the extents and limits of the WCC theory (Frith, 10 1989).     

Work addiction is associated with increased stress and reduced quality of life: Validation of the Bergen Work Addiction Scale in Danish

Addiction to work is defined as a compulsion or an uncontrollable need to work incessantly. Only few measures exist to identify work addiction and the health consequences are sparsely explored. The Bergen Workaholic Scale (BWAS) measures seven core elements of work addiction and has been used in Norway, Hungary, Brazil, Italy, USA and Poland. The aim of this study was to validate the BWAS in a Danish sample and to investigate if high risk of work addiction was associated with stress and reduced quality of life. We conducted an online screening survey with 671 participants aged 16–68 years with the Danish translation of the BWAS. We added the perceived stress scale (PSS) and the quality of life scale EQ‐5D‐5L. Those with high risk of work addiction reported significantly higher mean PSS scores (20.0 points) compared to those with low risk of addiction (12.5 points) and poorer quality of life (61.9) compared to the low risk group (81.3). Furthermore, work addiction was associated with more weekly working hours (44.0 vs. 35.6 hours/week) and having more leadership responsibility. A preliminary estimate of work addiction prevalence was 6.6%. The BWAS demonstrated good reliability (α = 0.83), and factor analyses pointed at a single factor structure. Work addiction seems to be associated with health problems in terms of stress and poorer quality of life. The BWAS is recommended as a reliable and valid tool to identify work addiction in Danish.     

Neuropsychological profile and neuroimaging in patients with 22Q11.2 Deletion Syndrome: a review.

22q11.2 Deletion Syndrome is associated with cognitive, behavioural, and psychiatric problems and is known to affect brain structure. Recently, 22q11.2 Deletion Syndrome has been proposed as a disease model for a genetic subtype of schizophrenia. In this paper we discuss the currently available literature on neurocognitive functioning and brain anatomy in patients with 22q11.2 Deletion Syndrome, and how this contributes to our understanding of the neurobiology of schizophrenia. Research on cognitive functioning in 22q11.2 Deletion Syndrome patients suggests a specific cognitive profile with impairments on arithmetical, visuo-spatial, and executive tasks and relatively preserved language skills. Prominent findings of neuroimaging studies in 22q11.2 Deletion Syndrome patients are: reduction of overall brain volume, midline defects, structural alterations of cerebellum and frontal lobe, white matter abnormalities, and decreased grey matter volumes in parietal and temporal areas. We describe how brain abnormalities in patients with 22q11.2 Deletion Syndrome may contribute to the understanding of the clinical syndrome including cognitive impairments, psychotic symptoms, and social and communication problems.