The Meaning of Childbearing Among IVF Service Users Assessed via Laddering Technique

The psychosocial issues related to infertility have been widely researched. However, the meaning a couple gives to childbearing remains a relatively unexplored area. This study explores the meaning making of Hong Kong Chinese couples who had received in-vitro fertilization (IVF). Eleven IVF-successful and seven IVF-unsuccessful informants were assessed using two complementary constructivist methods: laddering technique and constructivist-grounded theory analysis of in-depth interviews. Findings revealed four aspects of symbolic meaning of childbearing focused on the informant's sense of self, cultural values, existential purpose, and relations with others. The results also depicted infertility as a form of disenfranchised grief, following ambiguous loss, underscoring the need for counselors to explore the meaning of childbearing among IVF service users and the impact on their self-narratives as a function of treatment outcome.     

Imitation in rats: Initial responding and transfer evidence

In two experiments, rats observed a conspecific demonstrator pushing a single manipulandum, a joystick, to the right or to the left for food reward before being given access to the joystick, for the first time, from a different orientation. In Experiment 1, rats that had observed left-pushing made more of their first three responses to the left than did rats that had observed right-pushing. In Experiment 2 the axis of joystick movement was rotated through 90° between observation and testing for half of the animals. These rats, like those that were tested with the joystick in the position it had occupied during demonstrator responding, showed a significant tendency to push the joystick in the same direction relative to their own bodies as had their demonstrators. These results, which cannot be explained in terms of stimulus-reinforcer learning, provide evidence that rats are capable of imitation, i.e. response, or response-reinforcer, learning by observation.     

Motor learning by observation: Evidence from a serial reaction time task

This study sought evidence of observational motor learning, a type of learning in which observation of the skilled performance of another person not only facilitates motor skill acquisition but does so by contributing to the formation of effector-specific motor representations. Previous research has indicated that observation of skilled performance engages cognitive processes similar to those occurring during action execution or physical practice, but has not demonstrated that these include processes involved in effector-specific representation. In two experiments, observer subjects watched the experimenter performing a serial reaction time (SRT) task with a six-item unique sequence before sequence knowledge was assessed by response time and/or free generation measures. The results suggest that: (1) subjects can acquire sequence information by watching another person performing the task (Experiments 1-2); (2) observation results in as much sequence learning as task practice when learning is measured by reaction times (RTs) and more than task practice when sequence learning is measured by free generation performance (Experiment 2, Part 1); and (3) sequence knowledge acquired by model observation can be encoded motorically--that is, in an effector-specific fashion (Experiment 2, Part 2).     

Risky Sexual Behavior of Multiple Partner Relations and Women’s Autonomy in Four Countries

Existent research reveals that inequitable gender-based power in relationships and intimate partner violence contribute to HIV rates among women in the developing world. This study uses a multi-country analysis to examine women’s autonomy in negotiating safe sex practices such as having sex with a partner with no other concurrent partner to reduce the risk of HIV/AIDS in Nigeria, Kenya, Malawi, and Nepal. The Demographic Health Survey data for Nigeria (2013), Kenya (2008–2009), Malawi (2010), and Nepal (2011) provide geographical variability as well as HIV risk variables. The sample included 16,540 women aged 15–49 years who self-identified as ever married. Factor analysis for women’s autonomy was conducted based on socio-cultural theory. Logistic regression was conducted and results identified decision-making, labor force participation, and individual autonomy as women autonomy factors significantly reduced the risk for HIV infection by having one sex partner who has only one sex partner. Other women autonomy factors related to lower risk for HIV include education, place of residence, and religion. Our study indicates that effective management of HIV transmission requires addressing women autonomy factors within the context of culture.     

Historical Knowledge as Perspectival and Rational: Remarks on the Annales School's Idea of History

There is an obvious parallel between foundationalism, which ignores history in working out the conditions of knowledge, and radical relativism, which contends that by virtue of its own historical character there is no way to choose among different interpretations, all of which are "equally good." Might it not be, rather, that the recent historicist attack on the very idea of rationality is as damaging as foundationalist objections against the plurality of conceptual schemes or frameworks? Can philosophy maintain the traditional distinction between the form and content of knowledge, between rationality and historicity _ between doxa and episteme ?     

Changes in the Participants in a Community-Based Positive Youth Development Program in Hong Kong: Objective Outcome Evaluation Using a One-Group Pretest-Posttest Design

Applied Research in Quality of Life - Project “P.A.T.H.S.” has been shown to be effective in promoting positive development outcomes among Chinese adolescents in the school context....     

Aging and the discrimination of 3-D shape from motion and binocular disparity

Two experiments evaluated the ability of younger and older adults to visually discriminate 3-D shape as a function of surface coherence. The coherence was manipulated by embedding the 3-D surfaces in volumetric noise (e.g., for a 55?% coherent surface, 55?% of the stimulus points fell on a 3-D surface, while 45?% of the points occupied random locations within the same volume of space). The 3-D surfaces were defined by static binocular disparity, dynamic binocular disparity, and motion. The results of both experiments demonstrated significant effects of age: Older adults required more coherence (tolerated volumetric noise less) for reliable shape discrimination than did younger adults. Motion-defined and static-binocular-disparity-defined surfaces resulted in similar coherence thresholds. However, performance for dynamic-binocular-disparity-defined surfaces was superior (i.e., the observers?? surface coherence thresholds were lowest for these stimuli). The results of both experiments showed that younger and older adults possess considerable tolerance to the disrupting effects of volumetric noise; the observers could reliably discriminate 3-D surface shape even when 45?% of the stimulus points (or more) constituted noise.     

Reconsolidation in humans opens up declarative memory to the entrance of new information

A consolidated memory recalled by a reminder enters a vulnerability phase (labilization), followed by a process of stabilization (reconsolidation). Several authors have suggested that the labilization of the consolidated memory makes the incorporation of new information possible. Here, we demonstrate updating in the framework of memory declarative reconsolidation in humans by giving an opportune verbal instruction. Volunteers learn an association between five cue-syllables (L1) and their respective response-syllables. Twenty-four hours later, the paired-associate verbal memory is labilized by exposing the subjects to the reminder, and then they receive the verbal Instruction of adding three new cue-response syllables (INFO) with their respective responses to the former list of five. The new information is incorporated into the single former L1-memory and both INFO and L1 are successfully retrieved on the third day. However, when the Instruction is not preceded by a proper reminder, or when the instruction omits the order of adding the INFO into the former L1-memory, we observed interference in retrieval of both the original and the new information, suggesting that they are encoded independently and coexist as separate memories.     

Hippocampal memory processes are modulated by insulin and high-fat-induced insulin resistance

Insulin regulates glucose uptake and storage in peripheral tissues, and has been shown to act within the hypothalamus to acutely regulate food intake and metabolism. The machinery for transduction of insulin signaling is also present in other brain areas, particularly in the hippocampus, but a physiological role for brain insulin outside the hypothalamus has not been established. Recent studies suggest that insulin may be able to modulate cognitive functions including memory. Here we report that local delivery of insulin to the rat hippocampus enhances spatial memory, in a PI-3-kinase dependent manner, and that intrahippocampal insulin also increases local glycolytic metabolism. Selective blockade of endogenous intrahippocampal insulin signaling impairs memory performance. Further, a rodent model of type 2 diabetes mellitus produced by a high-fat diet impairs basal cognitive function and attenuates both cognitive and metabolic responses to hippocampal insulin administration. Our data demonstrate that insulin is required for optimal hippocampal memory processing. Insulin resistance within the telencephalon may underlie the cognitive deficits commonly reported to accompany type 2 diabetes.