Three experiments were conducted in an attempt to clarify the facilitatory influence of hydrocortisone on shock-induced fighting in rats. Results of the first experiment indicated a biphasic, dose-dependent action of intraventricularly-administered hydrocortisone. Low (25 μg) and intermediate (50 μg) doses both facilitated fighting whilst the high (100 μg) dose exerted a potent suppressant effect. Two control tests were performed to determine whether alterations in pain reactivity or locomotor activity could have accounted for the observed changes in fighting behaviour. None of the treatments altered shock thresholds (Experiment 2) but whilst neither low nor intermediate doses affected activity measures, the high dose preferentially reduced vertical activity (Experiment 3). 相似文献
Our objective was to examine the differential effects of antenatal breastfeeding intention (BI) and breastfeeding practice (BP) on maternal postnatal responsiveness. We conducted a secondary analysis of longitudinal data from a subsample of 962 mother–infant dyads from a U.K.-based birth cohort study the Avon Longitudinal Study of Parents and Children. Exposures were BI and BPs measured at 32 weeks of gestation and 18 months’ postpartum. The outcome was maternal responsiveness assessed at 12 months’ postpartum. We used logistic regression analyses unadjusted and adjusted for confounders. Intention to breastfeed was associated with increased odds of postnatal maternal responsiveness independent of BP, adjusted odds ratio (OR) = 2.34, 95% CI [1.42, 3.86]. There was no evidence that BP was an independent predictor of maternal responsiveness, OR = 0.93, 95% CI [0.55, 1.57]. Life-course epidemiology analyses demonstrated that maternal responsiveness is most positive when both BI and BP are present. This is the first population-based study to provide evidence that BI during pregnancy is more strongly associated with maternal postnatal responsiveness than is BP. Further research is needed to understand the determinants of BI in pregnancy and its relationships with maternal responsiveness. 相似文献
The measurement of wellbeing provides an important indicator of the welfare of nations and presents opportunities for policy making. Researchers generally share the view of wellbeing as a multidimensional concept. The 2012 European Social Survey (ESS) measurement of personal and social wellbeing, a combination of theoretical models and evidence from statistical analysis, is defined as a six-dimensional construct: evaluative wellbeing, emotional wellbeing, functioning, vitality, community wellbeing and supportive relationships. In this paper, the proposed theoretical structure is investigated and the psychometric properties of the measure are assessed for 17 European countries. This involved splitting each country’s sample randomly into halves and performing Exploratory Factor Analysis (EFA) on the first half-samples. EFA resulted in a four-factor solution for Germany, Netherlands, Portugal, Slovenia, Spain, Switzerland and the UK, a five-factor solution for Belgium, Finland, France, Ireland, Norway, Poland, Russian Federation and Sweden, and a six-factor solution for Denmark and Hungary. These results were supported by Confirmatory Factor Analysis (CFA) performed on the second half-samples. Subscales were constructed based on analysis of the total samples, applying a simple transformation in order to deal with the different number of response categories used for the wellbeing items. Reliabilities and internal consistencies were investigated. Although the definition of each subscale differs from the proposed structure and across countries, the analysis did produce reliable and valid summary measures (subscales) of wellbeing for informing social policy in each country.
Two experiments document that conceptual knowledge influences 3-year-olds' extension of novel words. In Experiment 1, when objects were described as having conceptual properties typical of artifacts, children extended novel labels for these objects on the basis of shape alone. When the very same objects were described as having conceptual properties typical of animate kinds, children extended novel labels for these objects on the basis of both shape and texture. Moreover, providing a salient perceptual cue (Experiment 2) did not interfere with children's reliance on conceptual information in extending novel words: when an object with eyes was labeled with a novel word in the context of a story describing the object as an artifact, children extended the label on the basis of shape alone (i.e. as though the object were an artifact). These results, which challenge directly the position that 'dumb attentional mechanisms' can account for word learning, stand as evidence for the central role of conceptual information in mapping words to meaning. 相似文献
In summary, giving up any of the three defining features of the Classic Experimental Design has (at least) two important effects. Each concession creates a significant threat to our confidence that any improvements observed were actually attributable to the treatment we are studying. At the same time, each concession opens a door by enhancing, sometimes greatly, the feasibility of conducting work in settings that are the most true to everyday clinical practice. When the work is thoughtfully and responsibly conducted, the alternative designs can contribute to clinical knowledge in a way that is equally important to the contributions made by work that conforms to the stringent requirements of the "Classic" design. In the next article, we will discuss single-time-point designs, along with the important dictum, memorized by most everyone who has taken a course called "Introduction to Research" or "Introduction to Statistics" that correlation is not causation. 相似文献
This study examined whether disinhibition shows similar relations with attention-deficit/hyperactivity disorder (ADHD) and conduct disorder (CD) symptomatology among male and female adolescents. The mixed-incentive or punishment condition of Newman's go/no-go task was administered to 172 adolescents. As expected, ADHD symptoms in boys and girls were predictive of disinhibition (i.e., commission errors) in the mixed-incentive but not punishment condition. Also consistent with expectations, CD symptoms in boys were predictive of disinhibition in the mixed-incentive but not punishment condition. In contrast, CD symptoms in girls were not predictive of disinhibition in either condition. These findings are discussed in terms of implications for understanding sex differences in the etiology of ADHD and CD. 相似文献
S. Roberts and H. Pashler (2000) argued against using goodness of fit as evidence to support theories. The authors agree with their suggestions for how to go beyond good fits but disagree with their starting point. In this comment, the authors argue that good fits are part and parcel of theory development, that they are part and parcel of the processes suggested by S. Roberts and H. Pashler, and that they must be the starting point (though far from the ending point) in theoretical development. The authors discuss historical examples of scientific theory development, recent examples of psychological theory development, and development of a particular theory (social contagion theory; J. L. Rodgers & D. C. Rowe, 1993) that S. Roberts and H. Pashler criticized. 相似文献
In this study, we investigated the Five-factor model in the concurrent prediction of positive symptom schizotypy as measured by the Magical Ideation (Eckblad & Chapman, 1983) and Perceptual Aberration (Chapman, Chapman, & Raulin, 1978) scales and negative symptom schizotypy as measured by the Physical Anhedonia (Chapman, Chapman, & Raulin, 1976) and Revised Social Anhedonia (Eckblad, Chapman, Chapman, & Mishlove, 1982; Mishlove & Chapman, 1985) scales. Previous studies suggest that these measures reflect the core symptoms found in schizotypal and schizoid personality disorder (Bailey, West, Widiger, & Freiman, 1993). Negative symptoms were significantly predicted by Neuroticism (+), Extraversion (-), Openness (-), and Agreeableness (-) domains of the Revised NEO Personality Inventory (NEO-PI-R; Costa & McCrae, 1992). Additionally, positive symptoms were significantly predicted by Neuroticism (+), Openness (+), and Agreeableness (-). In addition, we examined the validity of lower order traits in de- scribing these symptoms of character pathology. These findings lend further support for the use of domain and facet scales of the NEO-PI-R in the identification of personality pathology. 相似文献