The basis for choice reaction time slowing in Alzheimer's disease

Slowed reaction time has been suggested as an early feature of Alzheimer's disease (AD), but the basis for this slowing has not been established. Patients with mild AD were compared with controls on a choice reaction time task, both cued (CCRT) and uncued (CRT). Initial and 1-year followup data were analyzed both as mean reaction times and as parameters of a fitted two-component quantitative model (the ex-Gaussian model). Slowing of CRT proved to be a sensitive test for AD. Slowing was due to changes in both the sensory/motor and the decisional components of the CRT model. However, these changes were found in both AD and slower, older controls. The modeling of CRT in AD is discussed.     

Intrafamilial sexual abuse: family-of-origin and family-of-procreation characteristics of female adult victims.

We examined connections between incest victims' family-of-origin and family-of-procreation characteristics in a sample of 40 American women who were in treatment for childhood or adolescent experiences of victimization. Retrospective data on their families-of-origin were collected along with their perceptions of current relationships with family members in the three-generational system. Results showed a close association between family-of-origin and family-of-procreation characteristics, especially in the areas of intergenerational intimacy, intergenerational fusion/individuation, and personal authority. A number of significant correlations were also found between subjects' past and present relationships with family-of-origin members and the dimensions of moral and religious orientation, achievement, and intellectual and cultural orientation, conflict, and control in their family-of-procreation. Some aspects of individual adjustment, including alienation, emotional discomfort, and defensiveness, were strongly related to various family-of-origin and family-of-procreation characteristics.     

Dilemmas in the pathway of the DSM-IV

It is argued that the format for developing recent versions of the Diagnostic and Statistical Manual of Mental Disorders (DSM) taxonomy is constrained in ways that seriously impair the quality of the product. These constraints include inappropriate assumption of a categorical model, ensured persistence of traditional categories of disorder, excessive concern with interdiagnostician agreement, insufficient attention to the issue of construct validity, and excessive preoccupation with clinician acceptance. These problems and certain others are illustrated with an analysis of the nosologic status of the schizophrenia construct. There is a significant danger that the adequacy of DSM-IV will be compromised by continuing difficulties of this sort.     

When Lightning Strikes: Reexamining Creativity in Psychotherapy

Creativity is paramount to the therapeutic process. This article explored the role of creativity in counseling and psychotherapy through a critical analysis of several key articles in a special issue of The Journal of Clinical Activities, Assignments, & Handouts in Psychotherapy Practice (L. L. Hecker, 2002). Implications for counselors/therapists and the future of the field are discussed.     

The role of the primary motor cortex during skill acquisition on a two-degrees-of-freedom movement task

One can partially eliminate motor skills acquired through practice in the hours immediately following practice by applying repetitive transcranial stimulation (rTMS) over the primary motor cortex. The disruption of acquired levels of performance has been demonstrated on tasks that are ballistic in nature. The authors investigated whether motor recall on a discrete aiming task is degraded following a disruption of the primary motor cortex induced via rTMS. Participants (N = 16) maintained acquired performance levels and patterns of muscle activity following the application of rTMS, despite a reduction in corticospinal excitability. Disruption of the primary motor cortex during a consolidation period did not influence the retention of acquired skill in this type of discrete visuomotor task.     

A simple and unified approach to human voluntary movements

In his provocative article, F. Mechsner (2004) advances the thesis that human voluntary movements are subject to "psychological" or "perceptual-cognitive" control and are thus organized "without regard to efferent patterns" (p. 355). Rather than considering in detail the experiments that he proffered by way of support, the present author discusses the degree to which that supposition has appeal on the grounds of simplicity and is defined in terms that are compatible with a unified science.     

Interaction of directional,neuromuscular and egocentric constraints on the stability of preferred bimanual coordination patterns

We investigated how the relative direction of limb movements in external space (iso- and non-isodirectionality), muscular constraints (the relative timing of homologous muscle activation) and the egocentric frame of reference (moving simultaneously toward/away the longitudinal axis of the body) contribute to the stability of coordinated movements. In the first experiment, we attempted to determine the respective stability of isodirectional and non-isodirectional movements in between-persons coordination. In a second experiment, we determined the effect of the relative direction in external space, and of muscular constraints, on pattern stability during a within-person bimanual coordination task. In the third experiment we dissociated the effects on pattern stability of the muscular constraints, relative direction and egocentric frame of reference. The results showed that (1) simultaneous activation of homologous muscles resulted in more stable performance than simultaneous activation of non-homologous muscles during within-subject coordination, and that (2) isodirectional movements were more stable than non-isodirectional movements during between-persons coordination, confirming the role of the relative direction of the moving limbs in the stability of bimanual coordination. Moreover, the egocentric constraint was to some extent found distinguishable from the effect of the relative direction of the moving limbs in external space, and from the effect of the relative timing of muscle activation. In summary, the present study showed that relative direction of the moving limbs in external space and muscular constraints may interact either to stabilize or destabilize coordination patterns.     

Loving, discernment, and distance: pastoral care in schizophrenia

Schizophrenia is very common in our society, yet many people, both clergy and lay, are afraid of it and do not know what to do when confronted with someone who suffers from the disorder. Strange ideas and behavior can be frightening for those who don't understand and often result in further marginalization, even within the church community. This article seeks to outline the main features of schizophrenia and considers how to deal with particular situations which may arise in pastoral care. It suggests ways of dealing with people who express religious delusions and also argues that the "staples" of pastoral care--relationship building, empathy and inclusion--may not always be appropriate in the care of people with schizophrenia, who often need a "safe distance" between themselves and others. Some practical advice for families is also offered.