A laboratory school comparison of mixed amphetamine salts extended release (Adderall XR) and atomoxetine (Strattera) in school-aged children with attention deficit/hyperactivity disorder

Mixed amphetamine salts extended release (MAS XR; Adderall XR) and atomoxetine (Strattera) were compared in children 6 to 12 years old with attention deficit/hyperactivity disorder (ADHD) combined or hyperactive/impulsive type in a randomized, double-blind, multicenter, parallel-group, forced-dose-escalation laboratory school study. Primary efficacy measure was the SKAMP (Swanson, Kotkin, Agler, M-Flynn, and Pelham) behavioral rating scale. Changes in mean SKAMP deportment scores from baseline were significantly greater for MAS XR (n = 102) than for atomoxetine (n = 101) overall (-0.56 and -0.13, respectively; p < .0001) and at each week (p < .001). Adverse events were similar for both treatment groups. The extended time course of action and greater therapeutic efficacy of MAS XR suggests that it is more effective than atomoxetine in children with ADHD.     

The Parents Matter! Program Interventions: Content and the Facilitation Process

The Parents Matter! Program (PMP) has developed three interventions for parents of 4th and 5th grade African-American children (9–12 years old). The overarching goal of all three interventions is to provide parents with knowledge, skills, and support for enhancing their efforts to raise healthy children. The interventions are: (1) Enhanced Communication and Parenting (five 2 -hour sessions), (2) Brief Communication and Parenting (single 2 -hour session), and (3) General Health (single 2 -hour session). This article discusses the development of these interventions, presents an overview of the content of each intervention, and discusses issues related to the facilitation/presentation of these interventions.     

MMPI-2 F scale as a predictor of acute versus chronic disorder classification

This study examined the relation between elevation of the infrequency (F) scale on the Minnesota Multiphasic Personality Inventory-2 (MMPI-2) and the classification of psychological disorders as chronic or acute in an outpatient mental health setting. MMPI-2 and clinician rating data at time of intake were considered for 158 adult patients from an outpatient clinic. The results indicate that elevation on the F scale is associated with more chronic disorders even after the influence of other variables, such as age and comorbidity of other disorders, is statistically accounted for These results are discussed in terms of the utility and incremental validity of including the F scale as part of diagnostic screening.     

Searching in the center: pigeons (Columba livid) encode relative distance from walls of an enclosure

Pigeons (Columba livia) searched for food hidden in the center of a square enclosure. On occasional tests without food, the enclosure was (a) unchanged from training (control tests), (b) moved to different corners of the testing room (corner tests), or (c) doubled in size (expansion tests). The birds showed localized search in the center of the enclosure on control and corner tests. On expansion tests, some birds searched near the center of the enclosure, suggesting relative-distance encoding. Other birds searched at locations that maintained the training distance from walls, suggesting absolute-distance encoding. These results are consistent with previous studies on chicks (Gallus gallus) in similar enclosures and contrast with previous results on pigeons' responses to expansions of discrete landmark arrays.     

Reorientation in a two-dimensional environment: I. Do adults encode the featural and geometric properties of a two-dimensional schematic of a room?

Adults searched for a goal in images of a rectangular environment. The goal's position was constant relative to featural and geometric cues, but the absolute position changed across trials. Participants easily learned to use the featural cues to find the target, but learning to use only geometric information was difficult. Transformation tests revealed that participants used the color and shape of distinct features to encode the goal's position. When the features at the correct and geometrically equivalent corners were removed, participants could use distant features to locate the goal. Accuracy remained above chance when a single distant feature was present, but the feature farthest from the goal yielded lower accuracy than one closer. Participants trained with features spontaneously encoded the geometric information. However, this representation did not withstand orientation transformations.     

The Smell Identification Test as a measure of olfactory identification ability in schizophrenia and healthy populations: a Rasch psychometric study

This study examines University of Pennsylvania Smell Identification Test (UPSIT; R. L. Doty, 1995) performance in 133 controls and 54 chronic, medicated outpatients with schizophrenia (SZ) using item-response theory modeling. Results show that UPSIT items contribute to 1 factor, cover a range of 8 standard errors of measurement, and articulate 3 ability levels. Although it is not difficult enough to discriminate among persons of above-average ability, the test has diagnostic utility in detecting moderate impairment. Independent of item difficulty, 13 items differentiate patients from controls. When 45 patients and 45 controls were matched on gender and age, patient accuracy remained significantly reduced. The findings support the test's utility and demonstrate how traditional data analysis is insensitive to complexities in test performance.     

Effect of upcoming reward type when rats press a lever for ethanol

Rats' operant responding for sucrose rewards in the 1st half of a session can vary directly with the conditions of reward in the 2nd half. The authors investigated whether that induction effect represented an animal model of emotive states. Rats pressed a lever for either ethanol or sucrose rewards in the 1st half of a 40-min session. The reward in the 2nd half of the session was, across conditions, 1% sucrose, a food pellet, or the same reinforcer delivered in the 1st half. When subjects responded for sucrose, upcoming reward type had little influence on responding in the 1st half of the session. However, when subjects responded for ethanol, upcoming 1% sucrose and food-pellet reinforcement both produced increases in responding. The results suggest that the procedure produced different emotive states, but further work is needed to support such a model. The results also have potential applied implications.     

Silent thoughts,spoken wishes: when candidate experience of the supervisor converges with patient fantasies

How and why a candidate's private experience of two supervisors emerged in patients' fantasies about them is explored. Four issues are examined in light of two control cases: (1) Patients divide, rather than split, the transference between supervisor and candidate, experiencing both ambivalently. (2) Even a patient with no knowledge of the supervisor's identity may have a fantasy of the supervisor that is congruent with the candidate's experience of the supervisor. (3) When new professional traits emerge in the candidate as he or she identifies with his or her mentor, the patient may attribute them to the invisible person in the room--the supervisor; the patient may intuit and be influenced by the candidate's feelings about the supervisor as well. (4) A patient's fantasies about the supervisor may reflect parallel process in reverse, whereby the patient discerns what is going on between supervisor and candidate through his or her treatment, just as the supervisor reads what is going on between patient and candidate through the candidate's reporting of the treatment. Because the trio is the truth of the training case, it seems fitting and empowering to acknowledge and analyze the role of the supervisor in the patient's mind.     

Using video modeling and reinforcement to teach perspective-taking skills to children with autism

We evaluated video modeling and reinforcement for teaching perspective-taking skills to 3 children with autism using a multiple baseline design. Video modeling and reinforcement were effective; however, only 2 children were able to pass an untrained task, indicating limited generalization. The findings suggest that video modeling may be an effective technology for teaching perspective taking if researchers can continue to develop strategies for enhancing the generalization of these new skills.