On the requirement of nitric oxide signaling in the amygdala for consolidation of inhibitory avoidance memory

Evidence suggests that the NO/sGC/PKG pathway plays a key role in memory processing but the actual participation of this signaling cascade in the amygdala during memory consolidation remains unknown. Here, we show that when infused in the amygdala immediately after inhibitory avoidance training, but not later, the NO synthase inhibitor L-NNA hindered long-term memory retention without affecting locomotion, exploratory behavior, anxiety state or retrieval of the avoidance response. The amnesic effect of L-NNA was not state-dependent and was mimicked by the soluble guanylyl cyclase inhibitor LY83583 and the PKG inhibitor KT-5823. On the contrary, post-training intra-amygdala infusion of the NOS substrate L-Arg, the NO-releasing compound SNAP or the non-hydrolysable analog of cGMP 8Br-cGMP increased memory retention in a dose-dependent manner. Co-infusion of 8Br-cGMP reversed the amnesic effect of L-NNA and LY83583 but not that of KT-5823. Our data indicate that the NO-induced activation of PKG in the amygdala is a necessary step for consolidation of inhibitory avoidance memory.     

Tangibles as predictors of customer satisfaction in sports services

This study investigates the power of tangible dimensions of service quality to predict customer satisfaction. For this purpose, we statistically controlled the effects of dimensions of service quality that describe social interaction between employees and customers, both functionally and relationally. A field survey was conducted with the participation of 556 customers of a sports centre. The results showed that tangible dimensions of service quality predicted an additional and significant amount of customer satisfaction variance, beyond the effects of service quality of the social interaction. The article concludes with the discussion of the implications of these results.     

Making sense of word senses: the comprehension of polysemy depends on sense overlap

Studies of polysemy are few in number and are contradictory. Some have found differences between polysemy and homonymy (L. Frazier & K. Rayner, 1990), and others have found similarities (D. K. Klein & G. Murphy, 2001). The authors investigated this issue using the methods of D. K. Klein and G. Murphy (2001), in whose study participants judged whether ambiguous words embedded in word pairs (e.g., tasty chicken) made sense as a function of a cooperating, conflicting, or neutral context. The ambiguous words were independently rated as having low, moderate, or highly overlapping senses to approximate a continuum from homonymy to metonymic polysemy. The effects of meaning dominance were examined. Words with highly overlapping meanings (e.g., metonymy) showed reduced effects of context and dominance compared with words with moderately or low overlapping meanings (e.g., metaphorical polysemy and homonymy). These results suggest that the comprehension of ambiguous words is mediated by the semantic overlap of alternative senses/meanings.     

Predictors of post-traumatic stress symptoms following occupational accidents: A longitudinal study

Objective: Occupational accidents are highly stressful events that frequently occur and impact both the physical and mental health of workers. The aim of this study was to longitudinally assess a predictive model of posttraumatic stress symptoms (PTSS) in workers who have suffered a recent accident. Method: Two hundred and forty-four workers (77.8% men), aged 18 to 73 years, who had experienced an accident during the last month that resulted in hospitalization and/or ten or more days of sick leave, were surveyed. A second survey was carried out six months later. Regression analyses included psychological predictors (i.e. subjective severity of event, brooding and positive and negative religious coping), along with objective predictors (i.e. hospitalization, sick leave days and unemployment). Results: It was found that the main predictors of PTSS were brooding, negative religious coping, days of sick leave and unemployment, with a large effect size (R²?=?.45). Conclusions: The discussion is based on the usefulness of including selected psychological and objective predictors for detecting people more susceptible to developing psychopathology due to the stress following an accident. Identifying at-risk people for developing PTSS after an accident may help to introduce selective preventive strategies or early interventions in this population.     

Age-related Changes in Postural Sway During Sit-to-stand in Typical Children and Children with Cerebral Palsy

Objective: To assess age-related changes in postural sway during sit-to-stand (STS) in typical children (TC) and children with mild cerebral palsy (CP). Methods: Thirty-five TC and 23 children with mild CP were allocated in four different age groups: 5–6, 7–9, 10–12, and 13–15 years; they all performed STS movements over a force plate. Anterior-posterior and medial-lateral amplitude of center of pressure (CoP) displacement, area and velocity of CoP sway were analyzed and compared between the age groups for TC and children with CP. Results: TC at 5 to 6 years of age showed higher values of anterior-posterior CoP displacement and Area of CoP sway than at 10–12 years, during the stabilization phase. There were no age-related changes for CP. Conclusion: TC change their postural sway during the last STS phase over the years, reducing their body sway. Children with CP did not show age-related changes in sway during STS, reflecting a distinct rhythm of postural control development in this population.     

On the Subjectivity of the Experience of Victory: Who Are the Election Winners?

Elections represent key moments in democratic countries, and an established finding from the existing literature is that winners of elections display higher levels of satisfaction with democracy. Yet we know almost nothing about the times when voters feel like winners of an election. Using panel data in four countries, this article finds that while the objective performance of the supported party—measured using vote share and changes in vote share from the previous election—has a very important effect on feeling like an election winner, prior expectations regarding the election’s outcome as well as preferences for the supported party significantly moderate the effect of party performance on voter feelings. It seems also that the identification of the winners and losers of elections are clearer in majoritarian‐style democracies than in proportional systems with coalition governments. Ultimately, the findings indicate that measuring who are the winners of an election using exclusively objective measures of party performance may provide a distorted view of public opinion following the elections.     

Psychological Follow-up of Presymptomatic Genetic Testing for Spinocerebellar Ataxia Type 2 (SCA2) in Cuba

Presymptomatic testing for spinocerebellar ataxia type 2 (SCA2) in Cuba started five years ago. We have now investigated the psychological impact of test results on 150 individuals at 50% risk for SCA2. In a prospective study, psychological instruments were used to evaluate depression, anxiety and family functioning (1) before testing and (2) one year after disclosure of the test result. One year after, anxiety and depression levels decreased both in carriers and non-carriers, but anxiety decreased significantly more in carriers. Pathological levels of anxiety were seen mostly in members of dysfunctional families, but decreased more in them than in other consultands. Presymptomatic testing thus seems to have been especially beneficial for these testees, possibly due to a greater gain from the psychosocial support received. It would be pertinent to evaluate now the impact of other psychosocial variables and perform longer-term longitudinal studies.     

The relationship between search efficiency and crowding

The role of target salience in crowding has remained controversial largely because salience usually escapes objective measurement. Here we address this problem using search efficiency as a measure of target salience. In separate experiments observers determined whether parafoveal arrays of vertical Gabor patterns contained targets having a unique colour, a unique direction of motion, and a unique temporal frequency. We analysed search efficiency in the conventional manner using reaction-time gradients (in seconds per item). We also considered accuracy gradients (in percent-correct per item). Crowding is typically quantified by comparing the acuity for a target within an array to the acuity for a target presented alone. We measured orientation acuity for determining whether a slightly tilted target was clockwise or anticlockwise of vertical. Targets with a unique colour or direction of motion were found to pop out, ie (with one exception) reaction-time and accuracy gradients were insignificantly different from zero. Acuity for these targets was significantly greater than acuity for targets whose neighbours had the same colour and direction of motion. Manipulation of temporal frequency produced a wide range of search efficiencies. For three of four observers we found a linear relationship between acuity and the accuracy gradient, shallow gradients being associated with high acuity. In general, we find that crowding is weakened when observers can find a parafoveally presented target quickly and accurately.