Exploration and avoidance in rats with lesions in amygdala and piriform cortex

Lesions localized to specific areas of the amygdala and overlying cortex in rats produced differential effects in several behavioral tasks. Three different types of lesions were tested: central, basolateral, and cortex lateral to the amygdala. Lesions restricted to the central nucleus produced increased activity on all parameters studied in an open-field test, but the other two groups were not changed. In one-way active avoidance all three groups with lesions showed deficits. The most pronounced change was observed in the central group. All groups showed the same degree of retention loss, but in forced extinction of one-way active avoidance after retraining, the cortical and basolateral groups were most defective. A fear-reduction hypothesis is proposed for the central lesion. The basolateral and cortical areas may be more specifically involved in passive avoidance behavior.     

Differential indications for desipramine--results of a controlled multiclinical study]

The antidepressants desipramine and imipramine were compared within the framework of a multiclinical study performed under the conditions of a controlled clinical experiment. There has been found a time-different remission of affective symptoms, which was not detectable for the inhibition of drive. The tachythymoleptic action of desipramine is discussed with reference to these results. Evaluation of the possibility of controlling affects shows different ranges of activity of desipramine and imipramine, with desipramine influencing especially negative psychoenergetic symptoms in the area of drives and emotions and imipramine, restrictive symptoms in addition to differential phenomena of the psychomotor expression.     

Why child neuropsychiatry?]

The author gives a brief survey of the development of Child-Neuropsychiatry in the G.D.R. and subsequently gives reasons for the decision in favor of the unity of neurology and psychiatry as applied to children and juveniles, which is in contrast to developments in other countries. In addition to hygienic, economic, organizational, and medical considerations, this decision was also determined by the fact that a Child-Neuropsychiatrist must, in his practical work as a subspecialist, be able to head a multiprofessional team and, thus, help assure optimum development of a child's personality.     

Evaluation of the relative effectiveness of methylphenidate and cognitive behavior modification in the treatment of kindergarten-aged hyperactive children

This study of kindergarten-aged hyperactive children evaluated the effects of three modes of treatment in relation to an untreated control group. The treatments were administered over a 3-month period and included cognitive behavior modification, methylphenidate, and the two treatments combined. A follow-up assessment was done approximately 1 year later at the end of the first grade. Analyses of psychological, rating scale observational, and interview data showed that hyperactive children became less symptomatic over time;the data did not provide evidence indicating that any of the treatments studied was more effective than any other or than no treatment at all.This research was supported by grants from the Ontario Mental Health Foundation (Grant No. 701-76/78) and The Hospital for Sick Children Foundation (Grant No. 77-22). The authors wish to thank Mr. Syl Sauro, of the Etobicoke Board of Education, and Mrs. M. Stijovic, of the Etobicoke Community Health Department, for their cooperation.     

When beauty isn't talent: The influence of physical attractiveness,attitudes toward women,and competence on impression formation

The present study investigated the effect of attitudes toward women, physical attractiveness, and competence on impression formation of women. Male and female undergraduates read a competent or incompetent essay allegedly written by a physically attractive or unattractive female and responded to questions about the essay and its writer. Subjects were classified as traditionals, moderates, or liberals on the basis of their scores on the Attitudes Toward Women Scale. Female subjects' impressions were affected by the competence of the stimulus person and by their sex-role attitudes, but were not influenced by the physical attractiveness of the writer. Males, however, were influenced by all three variables. Evidence was found for a reversal of the physical attractiveness stereotype for liberal males with reference to incompetent women. The implications of these findings for physical attractiveness research are discussed.The authors wish to express their appreciation to Walter Stephan, Judith Langlois, Janet Spence, and Richard Archer for their helpful comments on an earlier draft of this article. Thanks are also due to Richard Roberson for assistance in data collection.     

The treatment of epilepsies with Convulsofin

The testing of Convulsofin carried out in 220 patients at 14 clinics over a period of six months confirms the international experience gained with valproic acid and sodium valproinate. The main field of application of Convulsofin according to the experience gained will again be the treatment of fits in generalised primary epilepsy for which it permits to carry out a monotherapy to a remarkable extent. The favourable effect of the preparation in photosensitivity could be confirmed. Also in generalised secondary epilepsy and in fits of partial epilepsy. Convulsofin is partly effective, so that it can recommended as a co-medication in the treatment of therapy-resistant forms of these epilepsies which are difficult to treat. Decrease in thrombocytes, transient increase in serum transaminases, gastrointestinal disorders, loss of hair and undesired increases in body-weight were the more frequently occurring side-effects.