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201.
Kremen WS Panizzon MS Xian H Barch DM Franz CE Grant MD Toomey R Lyons MJ 《Psychology and aging》2011,26(4):852-863
Studies comparing young and older adults suggest a deficit in processing context information as a key mechanism underlying cognitive aging. However, the genetic architecture of context processing has not been examined. Consistent with previous results, we found evidence of functionally dissociable components of context processing accuracy in 1127 late middle-aged twins ages 51-60. One component emphasizes use of context cues to prepare responses (proactive cognitive control), and the other emphasizes adjustment of responses after probes are presented (reactive control). Approximately one-quarter of the variance in each component was accounted for by genes. Multivariate twin analysis indicated that genetic factors underlying two important components of context processing were independent of one another, thus implicating more than one underlying mechanism. Slower reaction time (RT) on noncontext processing trials was positively correlated with errors on the strongly proactive control component on which young adults outperform older adults, but RT was negatively correlated with errors on the strongly reactive control component on which older adults perform better. Although this RT measure was uncorrelated with chronological age in our age-homogeneous sample, slower RT was associated with performance patterns that were more like older adults. However, this did not generalize to other processing speed measures. Genetic correlations, which reflect shared genetic variance, paralleled the phenotypic correlations. There was also a positive genetic correlation between general cognitive ability and accuracy on the proactive control component, but there were still mostly distinct genetic influences underlying these measures. In contrast, the reactive control component was unrelated to general cognitive ability. 相似文献
202.
Hong BA North CS Pollio DE Abbacchi A Debold C Adewuyi SA Lisker-Melman M 《Journal of clinical psychology in medical settings》2011,18(1):99-107
The standard of care treatment for chronic hepatitis C viral infection (HCV) is a combination of pegylated interferon alfa and ribavirin for 24-48?weeks according to the virus genotype. This therapy is known to have multiple neuropsychiatric side effects. A major concern when evaluating a patient for HCV treatment with a known history of a psychiatric disorder is the risk that the patient's psychiatric disorder will flare or become unmanageable. The possibility of precipitating depression, confusion, mania, psychosis, hallucinations, or suicidal ideation or attempt is frequently an obstacle to treatment. We present the case of a 50?year-old man with HCV and an extensive psychiatric history involving alcoholism, depression, and suicidality who participated in a psychoeducation group to help prepare him for treatment with pegylated interferon alfa/ribavirin therapy. Though the patient derived much benefit from the psychoeducation group, by the time of evaluation for HCV treatment two months after the group ended he had relapsed back into a depressive episode with suicidal thoughts. His acute psychiatric status made him unacceptable for pegylated interferon alfa/ribavirin therapy. Psychoeducation groups show promise for helping patients with chronic medical illness to be ready for and endure intensive medical treatment that has substantial psychiatric side effects. The challenge is to help patients overcome barriers to treatment, particularly psychosocial problems, because available treatments are increasingly effective. 相似文献
203.
204.
Claire Penn Jennifer Watermeyer Carol MacDonald Colleen Moabelo 《Journal of genetic counseling》2010,19(1):9-21
With its diverse cultural and linguistic profile, South Africa provides a unique context to explore contextual influences
on the process of genetic counseling. Prior research suggests intergenerational differences regarding models of causation
which influence treatment-seeking paths. This pilot study therefore aimed to explore South African traditional beliefs regarding
common childhood genetic disorders. Three focus groups were conducted with fifteen grandmothers from different cultural backgrounds
in an urban community. Questions pertained to the role of the grandmother, traditional beliefs regarding causes of genetic
disorders, explanations of heredity, and prevention and management of genetic disorders. Results indicate a variety of cultural
explanations for causes of childhood genetic disorders. These causes can be classified into categories related to lifestyle,
behavior, social issues, culture, religion, genetic, and familial causes. Prevention and treatment issues are also highlighted.
These findings have implications for genetic counseling practice, which needs to include a greater focus on cultural issues. 相似文献
205.
English exhibits compensatory shortening, whereby a stressed syllable followed by an unstressed syllable is measured to be shorter than the same stressed syllable alone. This anticipatory shortening is much greater than backward shortening, whereby an unstressed syllable is measured to shorten a following stressed syllable. We speculated that measured shortening reflects not true shortening, but coarticulatory hiding. Hence, we asked whether listeners are sensitive to parts of stressed syllables hidden by following or preceding unstressed syllables. In two experiments (Experiments 1A and 1B), we found the point of subjective equality—that is, the durational difference between a stressed syllable in isolation and one followed by an unstressed syllable—at which listeners cannot tell which is longer. In a third experiment (Experiment 2), we found the point of subjective equality for stressed monosyllables and disyllables with a weak-strong stress pattern. In all of the experiments, the points of subjective equality occurred when stressed syllables in disyllables were measured to be shorter than those in monosyllables, as if the listeners heard the coarticulatory onset or the continuation of a stressed syllable within unstressed syllables. 相似文献
206.
采用“5/4模型”类别结构探讨了类别学习中样例量的预期作用。设置了两种学习条件(“知道样例量”和“不知道样例量”), 分别探讨两种学习条件下的学习效率、学习策略以及所形成的类别表征。106名大学生参加了实验, 结果表明:在类别学习中, 样例量的预期作用显著, 知道样例量组的学习效率高于不知道样例量组; 样例量的预期作用对类别学习效率的影响是通过影响学习过程中使用的策略来实现的; 样例量的预期作用不影响两种学习条件的学习后形成的类别表征, 且两种学习条件的被试自始至终表现出样例学习的表征模式。 相似文献
207.
A new multiple indicator method of assessing bullying behaviour is employed (Direct and Indirect Prisoner behaviour Checklist - Scaled version [DIPC-SCALED]) with 605 adult prisoners (487 men and 118 women). The study explores if the DIPC-SCALED is a reliable method comprising of identifiable aggression factors; if prisoners can be classified into groups based on behavioural frequency; and if there is evidence for mutual victim/perpetrator groups. The DIPC-SCALED proved reliable, comprising of a number of aggression factors. Prisoners could be classified into groups based on behavioural frequency with one-fifth classified into an "intense" perpetrator and/or victim group. Evidence for mutual perpetrator/victims was found. Results are discussed with regards to the method used and the value in accounting for behavioural frequency in group classification. 相似文献
208.
Majer JM Jason LA North CS Ferrari JR Porter NS Olson B Davis M Aase D Molloy JP 《American journal of community psychology》2008,42(1-2):145-153
A longitudinal analysis of psychiatric severity was conducted with a national sample of recovering substance abusers living in Oxford Houses, which are self-run, self-help settings. Outcomes related to residents' psychiatric severity were examined at three follow-up intervals over one year. Over time, Oxford House residents with high versus low baseline psychiatric severity reported significantly more days using psychiatric medication, decreased outpatient psychiatric treatment, yet no significant differences for number of days abstinent and time living in an Oxford House. These findings suggest that a high level of psychiatric severity is not an impediment to residing in self-run, self-help settings such as Oxford House among persons with psychiatric comorbid substance use disorders. 相似文献
209.
Lahey BB Van Hulle CA D'Onofrio BM Rodgers JL Waldman ID 《Journal of abnormal child psychology》2008,36(6):807-823
Recent studies suggest that most of what parents know about their adolescent offspring's whereabouts and companions is the result of youth disclosure, rather than information gained through active parental monitoring. This raises the possibility that parental knowledge is spuriously correlated with youth delinquency solely because the most delinquent youth disclose the least information to parents (because they have the most to hide). We tested this spurious association hypothesis using prospective data on offspring of a nationally representative sample of US women, controlling demographic and contextual covariates. In separate analyses, greater parental knowledge of their offspring's peer associations at both 12-13 years and at 14-15 years was associated with lower odds of being in the top 1 standard deviation of youth-reported delinquency at 16-17 years, controlling for delinquency at the earlier ages. The extent to which parents set limits on activities with peers at 14-15 years did not mediate or moderate the association between parental knowledge and delinquency, but it did independently predict future delinquency among adolescents living in high-risk neighborhoods. This suggests that the association between parental knowledge and future delinquency is not solely spurious; rather parental knowledge and limit setting are both meaningful predictors of future delinquency. 相似文献
210.
Francine Conway Carol Magai Carolyn Springer Samuel C. Jones 《Journal of research in personality》2008
This study examines the role of personality in predicting psychological and physical health among grandmothers who are coping with a non-normative non-traumatic stressor, i.e. serving as primary caregivers for their grandchildren. Using the Life Orientation Test-Revised (LOT-R), a measure of personality disposition, we examine the contributions of both optimism and pessimism to health outcomes. ANOVAs and regression analyses of the LOT-R and self reports of health in 67 African American and Latino grandmothers revealed psychological (obsessive compulsive symptoms, depression, hostility) and physical (sleep disorder, hypertension) health outcomes are differentially predicted by optimism and pessimism among older and younger age-groups of grandmothers. Implications for grandmothers’ response to caregiving stress and for future studies of personality’s relation to health are discussed. 相似文献