Cognitive-behavioral therapy for ADHD in medication-treated adults with continued symptoms

The purpose of the present study was to examine the potential efficacy, patient acceptability, and feasibility of a novel, cognitive-behavioral therapy (CBT) for adults with attention-deficit hyperactivity disorder (ADHD) who have been stabilized on medications but still show clinically significant symptoms. Thirty-one adults with ADHD and stable psychopharmacology for ADHD were randomized to CBT plus continued psychopharmacology or continued psychopharmacology alone. Assessments included ADHD severity and associated anxiety and depression rated by an independent evaluator (IE) and by self-report. At the outcome assessment, those who were randomized to CBT had lower IE-rated ADHD symptoms (p < .01) and global severity (p < .002), as well as self-reported ADHD symptoms (p < .0001) than those randomized to continued psychopharmacology alone. Those in the CBT group also had lower IE-rated and self-report anxiety (p's < .04), lower IE-rated depression (p < .01), and a trend to have lower self-reported depression (p = .06). CBT continued to show superiority over continued psychopharmacology alone when statistically controlling levels of depression in analyses of core ADHD symptoms. There were significantly more treatment responders among patients who received CBT (56%) compared to those who did not (13%) (p < .02). These data support the hypothesis that CBT for adults with ADHD with residual symptoms is a feasible, acceptable, and potentially efficacious next-step treatment approach, worthy of further testing.     

Facilitative orthographic neighborhood effects: the SERIOL model account

A large orthographic neighborhood (N) facilitates lexical decision for central and left visual field/right hemisphere (LVF/RH) presentation, but not for right visual field/left hemisphere (RVF/LH) presentation. Based on the SERIOL model of letter-position encoding, this asymmetric N effect is explained by differential activation patterns at the orthographic level. This analysis implies that it should be possible to negate the LVF/RH N effect and create an RVF/LH N effect by manipulating contrast levels in specific ways. In Experiment 1, these predictions were confirmed. In Experiment 2, we eliminated the N effect for both LVF/RH and central presentation. These results indicate that the letter level is the primary locus of the N effect under lexical decision, and that the hemispheric specificity of the N effect does not reflect differential processing at the lexical level.     

Mapping the MMPI-2 Restructured Clinical scales onto normal personality traits: evidence of construct validity

The MMPI-2 Restructured Clinical (RC; Tellegen et al., 2003) scales were developed to remove common factor variance that saturates the clinical scales and create a more distinct set of measures, yielding a new set of scales with improved convergent and discriminant validity. In this study, we examined the relation between RC scale scores and scores on the Multidimensional Personality Questionnaire (MPQ; Tellegen, in press), a measure of normal personality, using a sample of 811 college students. The results indicate strong convergence between the RC scales and expected MPQ higher order factors and primary scales. The RC scales also demonstrated expected improved convergent and discriminant validity over the clinical scales.     

Forgetting of trauma cues in adults reporting continuous or recovered memories of childhood sexual abuse

According to betrayal trauma theory, adult survivors of childhood sexual abuse (CSA) who were molested by their caretakers (e.g., a father) are especially likely to dissociate ("repress") their memories of abuse. Testing college students, some reporting CSA, DePrince and Freyd (2004) found that those scoring high on a dissociation questionnaire exhibited memory deficits for trauma words when they viewed these words under divided-attention conditions. Replicating DePrince and Freyd's procedure, we tested for memory deficits for trauma words relative to neutral words in adults reporting either continuous or recovered memories of CSA versus adults denying a history of CSA. A memory deficit for trauma words under divided attention was expected in the recovered-memory group. Results were inconsistent with this prediction, as all three groups exhibited better recall of trauma words than neutral words, irrespective of encoding conditions.     

Priming prepositional-phrase attachment during comprehension

Strong evidence suggests that prior syntactic context affects language production (e.g., J. K. Bock, 1986). The authors report 4 experiments that used an expression-picture matching task to investigate whether it also affects ambiguity resolution in comprehension. All experiments examined the interpretation of prepositional phrases that were ambiguous between high and low attachment. After reading a prime expression with a high-attached interpretation, participants tended to interpret an ambiguous prepositional phrase in a target expression as highly attached if it contained the same verb as the prime (Experiment 1), but not if it contained a different verb (Experiment 2). They also tended to adopt the high-attached interpretation after producing a prime with the high-attached interpretation that included the same verb (Experiment 3). Finally, they were faster to adopt a high-attached interpretation after reading an expression containing the same verb that was disambiguated to the high-attached versus the low-attached interpretation (Experiment 4).     

Studying individual aging in an interindividual context: typical paths of age-related, dementia-related, and mortality-related cognitive development in old age

This study has 2 objectives: (a) to explore typical paths of cognitive development associated with aging, terminal decline, and dementia and (b) to promote and illustrate an individual-oriented approach to the study of cognitive aging based on longitudinal panel data from a population-based sample (N = 500; age range-sub(T1)= 60-80, where T refers to time) tested at 3 occasions 5 years apart. Results document interindividual differences in multivariate patterns of change. Although cognitive changes generally covary, the present study indicates that subgroups of individuals develop along different paths characterized by selective changes in subsets of cognitive functions. Typical progression of dementia followed a developmental cascade from low declarative memory, via low functioning across all observed cognitive measures, to dementia diagnosis, and finally, death.