Childhood Factors that Precede Drug Injection: Is there a Link?

Examination of childhood risk factors for injection drug use may provide clues as to why people progress to injection drug use and it can promote identification of at-risk youth. We surveyed current injection drug users (IDUs) and individuals who never injected drugs (non-IDUs), recruited through street outreach and snowball sampling in Denver, CO. Between March 2000 and October 2003, 601 subjects (339 IDUs and 262 non-IDUs) participated in structured interviews. We examined self-reported factors in childhood that may have been influential in whether one progressed to drug injection later in life. These indicators included age at drug and alcohol initiation, childhood risk behavior, parental monitoring, family stability, and other family problems. Differences between IDUs and non-IDUs were assessed using unadjusted tests and logistic regression. Results of the data analysis indicated that IDUs were significantly younger when they first used both alcohol and marijuana, they reported higher childhood risk behavior scores, and they had less parental monitoring and less family stability as children than non-IDUs. This research may assist clinicians in defining factors that put youth at risk for problems associated with injection drug use.     

To press or not to press? Differential receptor expression and response to novelty in rats learning an operant response for reward

Learning to perform instrumental tasks is an ability of all animals. In a population of rats, not all individuals will acquire an operant response for reward. We hypothesized that there could be a genetic explanation for differences between High Consumers (those that acquired the lever press response) and Low Consumers (lever press response is low). Additionally, we proposed that this genetic difference could produce measurable changes in response to novelty. Wistar rats were trained to lever press for a 0.2% saccharin reward and on the 10th day they were placed in a novel open field for 30 min to record locomotor activity. The prefrontal cortex and hippocampus were dissected and qPCR was used to measure mRNA expression. A significant difference (p=.048; 2-way ANOVA) in gene expression was observed between Low and High Consumers. A principal component analysis (PCA), to cluster which genes represent this difference, identified 4 genes; 5-HT2A and mGlu1 in the hippocampus and AMPA GluR1 and adrenergic alpha2A in the prefrontal cortex. Response to a novel open field also differed since Low Consumers displayed a higher Total Distance in comparison to High Consumers. Additionally, Low Consumers could be subdivided into Low-Lever (with lever press response only when water deprived) and Low-Non-Lever (lever press response is low throughout training). PCA with this subdivision identified an additional nine genes differing within the divisions; NMDA NR2B and GABAAalpha3 in the prefrontal cortex and adrenergic alpha2B and alpha2A, AMPA GluR1, GluR2 and GluR3, 5-HT1B and GABAAalpha5 in the hippocampus.     

Talking about interest: exploring the role of social interaction for regulating motivation and the interest experience

The Self-Regulation of Motivation Model suggests that the experience of interest is an important source of human motivation and that people often strategically regulate the experience of interest. Previous work based on this model suggests that the social context may influence this process at multiple points. The present research focuses on whether talking to others about an activity experience is one means by which individuals evaluate how interesting that activity is. In Study 1 college students completed questionnaires that asked about real life experiences where working on an activity was more interesting because they worked with others. They described experiences that occurred first in any domain, and then that occurred specifically in the school domain. Results suggested that the more students talked with others about the activity after it happened the more they reported greater interest in the activity after the conversations. In the school domain, this was especially true for Latinos and for individuals who scored higher on the Relational Self-Construal scale. Study 2 employed a lab paradigm to control for the task that individuals talked to others about and to examine whether the nature of listeners’ reactions influenced the speaker’s interest even after the study was ostensibly over. First, replicating Pasupathi and Rich (2005, ‘Inattentive listening undermines self-verification in personal storytelling’, Journal of Personality 73, pp. 1051–1086) college students who talked to a distracted friend about a computer game during the lab session reported a significant drop in interest relative to those who talked to attentive friends, regardless of whether the attentive listeners agreed or disagreed with participants. Importantly, interest ratings at a 4–6 week follow-up were affected by the perceived responsiveness of listeners during spontaneous conversational retellings outside the lab, controlling for interest levels at the end of the lab session. Taken together, results suggest that social interaction plays an important role in regulating activity interest even beyond the immediate activity experience.     

If She’s a Feminist it Must Not be Discrimination: The Power of the Feminist Label on Observers’ Attributions About a Sexist Event

This study examined the reactions of 207 undergraduate women (mean age?=?20.6, 91.3% White) from a Northeastern U.S. university to a scenario in which a feminist or non-feminist woman did or did not indicate that gender discrimination was the reason that she was passed over for a leadership role. Participants rated the feminist woman as less a victim of discrimination and as more of a complainer than the non-feminist woman. Participants also had a more positive impression of the woman and rated her as less of a complainer when discrimination was certain or ambiguous than when there was little evidence of discrimination. Discussion considers how a feminist label may lead to discounting the possibility of gender discrimination.     

Gender Differences in the Perception of Prisoner Abuse

We examined gender stereotypes and perceptions of aggression in 743 US psychology students at a northeastern university in the USA. Participants rated a vignette depicting torture of an Iraqi prisoner by an American soldier in which the gender of prisoner and guard were varied. The results showed that female participants viewed torture more negatively than male participants. Additionally, participants perceived the torture and killing of a female prisoner warranted significant compensation to her family. However, participants perceived violent acts by a male guard to be as serious as for a female guard, suggesting a shift in perceptions of gender role stereotypes. Our findings demonstrate a change in the gender role stereotyping for females in the military and suggest a number of future studies.     

The neural correlates of social attention: automatic orienting to social and nonsocial cues

Previous evidence suggests that directional social cues (e.g., eye gaze) cause automatic shifts in attention toward gaze direction. It has been proposed that automatic attentional orienting driven by social cues (social orienting) involves a different neural network from automatic orienting driven by nonsocial cues. However, previous neuroimaging studies on social orienting have only compared gaze cues to symbolic cues, which typically engage top-down mechanisms. Therefore, we directly compared the neural activity involved in social orienting to that involved in purely automatic nonsocial orienting. Twenty participants performed a spatial cueing task consisting of social (gaze) cues and automatic nonsocial (peripheral squares) cues presented at short and long stimulus (cue-to-target) onset asynchronies (SOA), while undergoing fMRI. Behaviorally, a facilitation effect was found for both cue types at the short SOA, while an inhibitory effect (inhibition of return: IOR) was found only for nonsocial cues at the long SOA. Imaging results demonstrated that social and nonsocial cues recruited a largely overlapping fronto-parietal network. In addition, social cueing evoked greater activity in occipito-temporal regions at both SOAs, while nonsocial cueing recruited greater subcortical activity, but only for the long SOA (when IOR was found). A control experiment, including central arrow cues, confirmed that the occipito-temporal activity was at least in part due to the social nature of the cue and not simply to the location of presentation (central vs. peripheral). These results suggest an evolutionary trajectory for automatic orienting, from predominantly subcortical mechanisms for nonsocial orienting to predominantly cortical mechanisms for social orienting.     

工作记忆的保持与操控：腹侧和背侧额叶皮层的特异性功能磁共振成像活动

为了进行大样本的老化与记忆的功能磁共振成像(fMRI)研究, 研究者设计了言语工作记忆的方案, 并且对一组健康青年人进行了施测。字母的呈现方式主要为两种条件: (i) 保持, 要求被试记住呈现的字母并且能够在4秒的间隔后保持; (ii) 操控, 被试需要将呈现的字母按字母表的顺序进行转换, 并且记住新的顺序。不管是用全脑分析, 还是用预先定义的感兴趣区域的分析方法, 对fMRI数据的分析表明本方案诱发了可靠的额叶皮层的激活, 且操控条件则引发了更为广泛的激活。背外侧和腹内侧前额叶的激活也表现出了不同特点, 操控引发了更多的背外侧前额叶激活。一些皮下区域也得到了激活, 特别是以前发现与工作记忆任务相关的一些区域。这说明该工作记忆研究方案适合探索额叶功能的与年龄相关的改变。     

How horses (Equus caballus) see the world: humans as significant “objects”

This study aimed to determine whether horses have a kind of memory of humans (based on previous interactions), leading to a general significance of humans revealed by their reactions to humans in subsequent interactions. Subjects were 59 adult horses used to interact daily with humans. Three types of behavioural tests involving an unknown experimenter evaluated three possibly different memorized types of human–animal interactions (not work-related, using work-related objects, unfamiliar working task). We also performed standardized observations of routine interactions between each horse and its familiar handler (caretaker). To get a broad overview of the horses’ reactions to humans, we recorded both investigative and aggressive behaviours during the tests, representing respectively a “positive” and a “negative” memory of the relationship. Whereas correlations between tests revealed a general perception of humans as either positive or negative, unusual tests, i.e. that are not usually performed, elicited more positive reactions. Moreover, some horses reacted positively to a motionless person in their box, but negatively when this same person approached them, for example for halter fitting. Overall, aggressive reactions were more reliable indicators of the relationship than positive reactions, both between tests and between familiar and unfamiliar humans. Our results also show generalization of the perception of humans. These results support our hypothesis that perception of humans by horses may be based on experience, i.e. repeated interactions. Altogether, our results support the hypothesis that horses can form a memory of humans that impacts their reactions in subsequent interactions.     

Solving Social Problems Like a Psychologist

ABSTRACT— We suggest that psychologists can play a larger role in the solution of important social problems. Psychology brings two important qualities to the study of social problems: attention to psychological process and rigorous methodology. Our key task is to define social problems in part as psychological problems, and to conduct rigorous research that tests novel psychological solutions. Examples of research that has taken this path—research on race differences in academic performance, on the training of executive function and intelligence, and on the provision of socially constructive default decisions—are provided. We argue that addressing social problems can enrich our science by connecting psychologists to interdisciplinary teams and by providing contexts in which to demonstrate, in striking ways, the value of a psychological approach.