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141.
Carlos Alberto Sánchez 《Continental Philosophy Review》2018,51(3):439-457
The focus of this paper is Mexican historicism. It has three objectives: first, to introduce English-speaking readers to the nature and history of Mexican historicism; second, to defend Mexican historicism against the charges of relativism usually raised against historicism in general and “Mexican” philosophy in particular; and third, to argue for what I call the transcendental, or alternatively, “liberatory,” nature of Mexican historicism—a nature with philosophical and political consequences. The hope is that by making the clarifications and determinations made here, the tradition of Mexican philosophy, of which Mexican historicism is a key moment, may find its place in the increasingly pluralistic US philosophical landscape. 相似文献
142.
Rico Fischer Carlos Ventura-Bort Alfons Hamm Mathias Weymar 《Cognitive, affective & behavioral neuroscience》2018,18(4):680-693
Response conflicts play a prominent role in the flexible adaptation of behavior as they represent context-signals that indicate the necessity for the recruitment of cognitive control. Previous studies have highlighted the functional roles of the affectively aversive and arousing quality of the conflict signal in triggering the adaptation process. To further test this potential link with arousal, participants performed a response conflict task in two separate sessions with either transcutaneous vagus nerve stimulation (tVNS), which is assumed to activate the locus coeruleus-noradrenaline (LC-NE) system, or with neutral sham stimulation. In both sessions the N2 and P3 event-related potentials (ERP) were assessed. In line with previous findings, conflict interference, the N2 and P3 amplitude were reduced after conflict. Most importantly, this adaptation to conflict was enhanced under tVNS compared to sham stimulation for conflict interference and the N2 amplitude. No effect of tVNS on the P3 component was found. These findings suggest that tVNS increases behavioral and electrophysiological markers of adaptation to conflict. Results are discussed in the context of the potentially underlying LC-NE and other neuromodulatory (e.g., GABA) systems. The present findings add important pieces to the understanding of the neurophysiological mechanisms of conflict-triggered adjustment of cognitive control. 相似文献
143.
Sergio E. Chaigneau Enrique Canessa Carlos Barra Rodrigo Lagos 《Behavior research methods》2018,50(3):972-988
It is generally believed that concepts can be characterized by their properties (or features). When investigating concepts encoded in language, researchers often ask subjects to produce lists of properties that describe them (i.e., the Property Listing Task, PLT). These lists are accumulated to produce Conceptual Property Norms (CPNs). CPNs contain frequency distributions of properties for individual concepts. It is widely believed that these distributions represent the underlying semantic structure of those concepts. Here, instead of focusing on the underlying semantic structure, we aim at characterizing the PLT. An often disregarded aspect of the PLT is that individuals show intersubject variability (i.e., they produce only partially overlapping lists). In our study we use a mathematical analysis of this intersubject variability to guide our inquiry. To this end, we resort to a set of publicly available norms that contain information about the specific properties that were informed at the individual subject level. Our results suggest that when an individual is performing the PLT, he or she generates a list of properties that is a mixture of general and distinctive properties, such that there is a non-linear tendency to produce more general than distinctive properties. Furthermore, the low generality properties are precisely those that tend not to be repeated across lists, accounting in this manner for part of the intersubject variability. In consequence, any manipulation that may affect the mixture of general and distinctive properties in lists is bound to change intersubject variability. We discuss why these results are important for researchers using the PLT. 相似文献
144.
Guerra GP Mello CF Bochi GV Pazini AM Fachinetto R Dutra RC Calixto JB Ferreira J Rubin MA 《Neurobiology of learning and memory》2011,96(2):324-332
Spermidine (SPD) is an endogenous polyamine that modulates N-methyl-D-aspartate (NMDA) receptor function, and has been reported to facilitate memory formation. In the current study we determined whether or not the PKA/CREB signaling pathway is involved in SPD-induced facilitation of memory of inhibitory avoidance task in adult rats. The post-training administration of the cAMP-dependent protein kinase (PKA) inhibitor, N-[2-bromocinnamylamino)ethyl]-5-isoquinoline sulfonamide [H-89, 0.5 ρmol intrahippocampal (ih)] or the antagonist of the NMDA receptor polyamine-binding site (arcaine, 0.02 nmol ih) with SPD (0.2 nmol ih) prevented memory improvement induced by SPD. Intrahippocampal administration of SPD (0.2 nmol) facilitated PKA and cAMP response element-binding protein (CREB) phosphorylation in the hippocampus 180 min, but not 30 min, after administration, and increased translocation of the catalytic subunit of PKA into the nucleus. Arcaine (0.02 nmol) and H-89 (0.5 ρmol) prevented the stimulatory effect of SPD on PKA and CREB phosphorylation. These results suggest that memory enhancement induced by the ih administration of SPD involves the PKA/CREB pathways in rats. 相似文献
145.
Carlos Acuña-Fariña Isabel Fraga Javier García-Orza Ana Piñeiro 《Journal of Cognitive Psychology》2013,25(8):1137-1165
The present paper focuses on the role of animacy in the processing of relative clauses (RCs) after complex NPs. We follow research by the Desmet et al. team on Dutch in exploring the role of animacy in Spanish RCs. We present data from a corpus study and two self-paced experiments and we compare the three studies and the Dutch and Spanish results. Our main objective is to fill important gaps in past research on the processing of adjunction ties in Spanish and to offer a more detailed exploration of grain effects in exposure-based accounts. In particular, we have sought both to analyse the match between corpus studies and online processing in Spanish much more closely than it has been until now and to see whether animacy could revert the well-established tendency of Spanish RCs to attach high inside the complex noun phrase. 相似文献
146.
147.
Antonio Nicolas Puente Carlos Faraco Douglas P. Terry Courtney Brown L. Stephen Miller 《Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition》2014,21(3):346-369
This investigation compared the neural correlates of inhibition in normal older adults (OAs) and OAs with mild cognitive impairment (MCI). It was hypothesized the MCI group would require a greater amount of resources for inhibition, and therefore display greater functional activation in specific regions of interest (ROIs). Twenty-six OAs without and 17 with MCI completed the Stroop task during functional neuroimaging, and completed additional out-of-scanner neuropsychological measures. During inhibition, there were minimal functional Magnetic Resonance Imaging (fMRI) differences found between groups in a priori specified ROIs and with post-hoc multiple regression analyses. However, these minimal differences did not survive corrected thresholds. Robust differences were found with several tasks of a neuropsychological screening battery. The results of this study suggest only very minimal group differences in fMRI activation during inhibition which may not reliably identify MCI, and this condition may be best detected by traditional neuropsychological techniques. 相似文献
148.
Alfonso Pitarque Alicia Sales Juan Carlos Meléndez Salvador Algarabel 《Scandinavian journal of psychology》2015,56(1):38-44
Aging is accompanied by an increase in false alarms on recognition tasks, and these false alarms increase with repetition in older people (but not in young people). Traditionally, this increase was thought to be due to a greater use of familiarity in older people, but it was recently pointed out that false alarms also have a clear recollection component in these people. The main objective of our study is to analyze whether the expected increase in the rate of false alarms in older people due to stimulus repetition is produced by an inadequate use of familiarity, recollection, or both processes. To do so, we carried out an associative recognition experiment using pairs of words and pairs of images (faces associated with everyday contexts), in which we analyzed whether the repetition of some of the pairs increases the rate of false alarms in older people (compared to what was found in a sample of young people), and whether this increase is due to familiarity or recollection (using a remember‐know paradigm). Our results show that the increase in false alarms in older people due to repetition is produced by false recollection, calling into question both dual and single‐process models of recognition. Also, older people falsely recollect details of never studied stimuli, a clear case of perceptual illusions. These results are better explained in terms of source‐monitoring errors, mediated by people's retrieval expectations. 相似文献
149.
150.
de Oliveira AR Reimer AE de Macedo CE de Carvalho MC Silva MA Brandão ML 《Neurobiology of learning and memory》2011,95(1):37-45
Excitation of the mesocorticolimbic pathway, originating from dopaminergic neurons in the ventral tegmental area (VTA), may be important for the development of exaggerated fear responding. Among the forebrain regions innervated by this pathway, the amygdala is an essential component of the neural circuitry of conditioned fear. The functional role of the dopaminergic pathway connecting the VTA to the basolateral amygdala (BLA) in fear and anxiety has received little attention. In vivo microdialysis was performed to measure dopamine levels in the BLA of Wistar rats that received the dopamine D(2) agonist quinpirole (1 μg/0.2 μl) into the VTA and were subjected to a fear conditioning test using a light as the conditioned stimulus (CS). The effects of intra-BLA injections of the D(1) antagonist SCH 23390 (1 and 2 μg/0.2 μl) and D(2) antagonist sulpiride (1 and 2 μg/0.2 μl) on fear-potentiated startle (FPS) to a light-CS were also assessed. Locomotor performance was evaluated by use of open-field and rotarod tests. Freezing and increased dopamine levels in the BLA in response to the CS were both inhibited by intra-VTA quinpirole. Whereas intra-BLA SCH 23390 did not affect FPS, intra-BLA sulpiride (2 μg) inhibited FPS. Sulpiride's ability to decrease FPS cannot be attributed to nonspecific effects because this drug did not affect motor performance. These findings indicate that the dopamine D(2) receptor pathway connecting the ventral tegmental area and the basolateral amygdala modulates fear and anxiety and may be a novel pharmacological target for the treatment of anxiety. 相似文献