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Post-retrieval effects of icv infusions of hemicholinium in mice are dependent on the age of the original memory 下载免费PDF全文
Boccia MM Blake MG Acosta GB Baratti CM 《Learning & memory (Cold Spring Harbor, N.Y.)》2006,13(3):376-381
CF-1 male mice were trained in an inhibitory avoidance task using a high footshock (1,2 mA, 50 Hz, 1 sec) in order to reduce the influence of extinction on retention performance. At 2, 7, 14, or 30 d after training, the first retention test was performed and hemicholinium (HC-3, 1.0 microg/mice), a specific inhibitor of high-affinity choline uptake in brain cholinergic neurons, was given intracerebroventricularly immediately after. Twenty four hours after treatment, mice were tested in an inhibitory avoidance task during five consecutive days, each 24 h apart. Retention performance was impaired by HC-3 when the first re-exposure took place at 2, 7, or 14 d, but the effect was no longer seen when re-exposure occurred 30 d after training. We did not find spontaneous recovery 21 d after training, when memory was retrieved 2 d after training and HC-3 was given immediately after. Although we cannot definitively discard a retrieval deficit, this lack of spontaneous recovery is in accordance with the storage-deficit interpretation. These results confirm and extend previous ones, suggesting that central cholinergic mechanisms are involved in the hypothetical reconsolidation memory processes of an inhibitory avoidance task in mice and also suggest that this participation depends on the "age" of the original memory trace. This implies that the vulnerability of a reactivated memory to a specific treatment, as the one used in this study, inversely correlates with the age of the original memory, and it is likely to determine memory reconsolidation processes. 相似文献
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Drawing on recent claims in the study of relationships, attachment, and emotion, the authors hypothesized that romantic love serves a commitment-related function and sexual desire a reproduction-related function. Consistent with these claims, in Study 1, brief experiences of romantic love and sexual desire observed in a 3-min interaction between romantic partners were related to distinct feeling states, distinct nonverbal displays, and commitment- and reproductive-related relationship outcomes, respectively. In Study 2, the nonverbal display of romantic love was related to the release of oxytocin. Discussion focuses on the place of romantic love and sexual desire in the literature on emotion. 相似文献
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Sharon Shavitt Jing Zhang Carlos J. Torelli Ashok K. Lalwani 《Journal of Consumer Psychology》2006,16(4):357-362
The commentaries by Aaker (2006), Meyers‐Levy (2006), and Oyserman (2006) extend the implications of the horizontal/vertical distinction described in our article (Shavitt, Lalwani, Zhang, & Torelli, 2006) in a number of interesting directions. We join these authors in calling for further research on horizontal and vertical individualism and collectivism constructs. We also highlight conceptual and structural issues that remain to be resolved and evaluate priming and other operational approaches to the study of horizontal and vertical individualism and collectivism. 相似文献
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Warren R. Stanton 《Current psychology (New Brunswick, N.J.)》2002,21(2):176-198
Stage theories are commonly used to represent the structure of cognitive processes in the domains of cognitive processing
and cognitive development. Hierarchical unidimensional theories consisting of a single sequence of stages through which development
proceeds in one direction only have predominated. However, a review of stage theories revealed that a two-dimensional, interactive
(multidimensional) structure is warranted. Particularly in the area of cognitive development, results of research have supported
subdivision of the stages of prominent unidimensional theories. Following this trend a small number of theorists have developed
multidimensional theories, most of which consist of a sequence of stages in which each stage contains a number of subsidiary
stages or levels. The emergence of a similar trend in other domains is examined, and the prospects of using an existing multidimensional
framework to enable future comparisons and integration of different stage theories is explored. 相似文献
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Based on Rijt-Plooij and Plooij's (1992) research on emergence of regression periods in the first two years of life, the presence of such periods in a group of 18 babies (10 boys and 8 girls, aged between 3 weeks and 14 months) from a Catalonian population was analyzed. The measurements were a questionnaire filled in by the infants' mothers, a semi-structured weekly tape-recorded interview, and observations in their homes. The procedure and the instruments used in the project follow those proposed by Rijt-Plooij and Plooij. Our results confirm the existence of the regression periods in the first year of children's life. Inter-coder agreement for trained coders was 78.2% and within-coder agreement was 90.1%. In the discussion, the possible meaning and relevance of regression periods in order to understand development from a psychobiological and social framework is commented upon. 相似文献
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Jonathan James McCreadie Lillie 《Sexuality & culture》2002,6(2):25-48
This article presents theoretical considerations based on cultural analysis approaches to studying pornography and sexuality
as a means of starting to suggest a new agenda for cyberporn research. By bringing to the forefront concepts of how subjectivity
and sexuality are produced within the computer/Internet apparatus, I hope to diversify the focus in cyberporn research away
from social science approaches and pre-Foucaultian assumptions of the subject which obscure understandings of new media and
cyberporn use. Through a summary of visual culture studies and reception studies of pornography, I argue that cyberporn must
be understood as contingent within the encoding and decoding processes and discourses of sexuality (Foucault) in which it
is produced and consumed. My focus here is the home office/terminal as the site of reception/cyberporn use. While there is
potential for a great variety of cultural analytic approaches to the study of cyberporn and how new media use influences sexuality,
I end with specific suggestions for researching cyberporn reception in the home.
The computer’s allure is more than utilitarian or aesthetic; it is erotic. Instead of a refreshing play with surfaces, as
with toys or amusements, our affair with information machines announces a symbiotic relationship and ultimately a mental marriage
to technology. Rightly perceived, the atmosphere of cyberspace carries the scent that once surrounded Wisdom. The world rendered
as pure information not only fascinates our eyes and minds, but also captures our hearts. We feel augmented and empowered.
Our hearts beat in the machines. This is Eros. (Michael Heim, The Metaphysics of Virtual Reality) 相似文献