Expressed emotion and Milan systemic intervention: a pilot study on families of people with a diagnosis of schizophrenia

This article presents the results of a pilot study carried out on families of people with a diagnosis of schizophrenia (high‐frequency users of psychiatric services) using a standardized version of systemic family intervention based on the Milan Approach (‘Circular Interview’). We used expressed emotion (EE) to compare and assess two homogeneous samples of families, a treatment group (n = 10) and a control group (n = 8). We found that families participating in circular interviews showed a reduction in criticism, while 30% of their members with a diagnosis of schizophrenia relapsed. Families not receiving treatment showed no changes in EE levels, while 62.5% of their members with a diagnosis of schizophrenia relapsed. Although the difference in relapse rates is not statistically significant, these results justify further studies on the use of nondirective systemic intervention with families of people with a diagnosis of schizophrenia.     

Movements execution in amnestic mild cognitive impairment and Alzheimer's disease

We evaluated the relationship between motor and neuropsychological deficits in subjects affected by amnestic Mild Cognitive Impairment (aMCI) and early Alzheimer's Disease (AD). Kinematics of goal-directed movement of aMCI and AD subjects were compared to those of age-matched control subjects. AD showed a slowing down of motor performance compared to aMCI and controls. No relationships were found between motor and cognitive performances in both AD and aMCI. Our results suggest that the different motor behaviour between AD and aMCI cannot be related to memory deficits, probably reflecting the initial degeneration of parietal-frontal circuits for movement planning. The onset of motor dysfunction in early AD could represent the transition from aMCI to AD.     

Primacy and recency effects in immediate free recall of sequences of spatial positions

This study evaluated the serial position curve based on free recall of spatial position sequences. To evaluate the memory processes underlying spatial recall, some manipulations were introduced by varying the length of spatial sequences (Exp. 1) and modifying the presentation rate of individual positions (Exp. 2). A primacy effect emerged for all sequence lengths, while a recency effect was evident only in the longer sequences. Moreover, slowing the presentation rate increased the magnitude of the primacy effect and abolished the recency effect. The main novelty of the present results is represented by the finding that better recall of early items in a sequence of spatial positions does not depend on the task requirement of an ordered recall but it can also be observed in a free recall paradigm.     

The relevance of castration and circumcision to the origins of psychoanalysis: 1. The medical context1

In this paper the author outlines and discusses the origins and the decline of castration and circumcision as a cure for the nervous and psychic disturbances in women and little girls between 1875 and 1905. The author argues that the opposition to this medical practice affected the conception of hysteria, promoting a distinction between sexuality and the genital organs, and the emergence of an enlarged notion of sexuality, during the period from Freud’s medical education to the publication of the Three Essays on the Theory of Sexuality. The hypothesis is put forward that Freud came directly in contact with the genital theory of the neurosis at the time of his training on the nervous disturbances in children with the paediatrician, Adolf Baginsky, in Berlin, in March 1886. It is hypothesized that this experience provoked in Freud an abhorrence of circumcision ‘as a cure or punishment for masturbation’, prompting an inner confrontation which resulted in a radical reorganization of the way of thinking about sexuality. It is also suggested that this contributed to Freud developing a capacity to stay with contradictions, something which would become a central quality of the psychoanalytic attitude.     

Multimodal encoding in a simplified model of intracellular calcium signaling

Many cells use calcium signaling to carry information from the extracellular side of the plasma membrane to targets in their interior. Since virtually all cells employ a network of biochemical reactions for Ca²⁺ signaling, much effort has been devoted to understand the functional role of Ca²⁺ responses and to decipher how their complex dynamics is regulated by the biochemical network of Ca²⁺-related signal transduction pathways. Experimental observations show that Ca²⁺ signals in response to external stimuli encode information via frequency modulation (FM) or alternatively via amplitude modulation (AM). Although minimal models can capture separately both types of dynamics, they fail to exhibit different and more advanced encoding modes. By arguments of bifurcation theory, we propose instead that under some biophysical conditions more complex modes of information encoding can also be manifested by minimal models. We consider the minimal model of Li and Rinzel and show that information encoding can occur by AM of Ca²⁺ oscillations, by FM or by both modes (AFM). Our work is motivated by calcium signaling in astrocytes, the predominant type of cortical glial cells that is nowadays recognized to play a crucial role in the regulation of neuronal activity and information processing of the brain. We explain that our results can be crucial for a better understanding of synaptic information transfer. Furthermore, our results might also be important for better insight on other examples of physiological processes regulated by Ca²⁺ signaling.     

Multimodal encoding in a simplified model of intracellular calcium signaling

Many cells use calcium signaling to carry information from the extracellular side of the plasma membrane to targets in their interior. Since virtually all cells employ a network of biochemical reactions for Ca²⁺ signaling, much effort has been devoted to understand the functional role of Ca²⁺ responses and to decipher how their complex dynamics is regulated by the biochemical network of Ca²⁺-related signal transduction pathways. Experimental observations show that Ca²⁺ signals in response to external stimuli encode information via frequency modulation (FM) or alternatively via amplitude modulation (AM). Although minimal models can capture separately both types of dynamics, they fail to exhibit different and more advanced encoding modes. By arguments of bifurcation theory, we propose instead that under some biophysical conditions more complex modes of information encoding can also be manifested by minimal models. We consider the minimal model of Li and Rinzel and show that information encoding can occur by AM of Ca²⁺ oscillations, by FM or by both modes (AFM). Our work is motivated by calcium signaling in astrocytes, the predominant type of cortical glial cells that is nowadays recognized to play a crucial role in the regulation of neuronal activity and information processing of the brain. We explain that our results can be crucial for a better understanding of synaptic information transfer. Furthermore, our results might also be important for better insight on other examples of physiological processes regulated by Ca²⁺ signaling.     

Preschoolers' beliefs about sex and age differences in emotionality

The goal of the present study was to assess preschoolers' beliefs about the frequency and intensity with which boys, girls, women, and men experience anger, sadness, and happiness. Sixty-seven middle-class preschool children (35 girls, 32 boys) were presented with drawings of adult and child figures of each sex, and were asked to rate how frequently and intensely the emotions were felt (91% of the children were white; the remainder were primarily black). Children's gender stereotyped beliefs were particularly strong for sadness and appeared to be based on a deficit-experience model for males. Sex of target differences also were found for children's beliefs about anger (favoring males). However, the sex difference in anger was based more on the degree to which anger is believed to be experienced rather than on differences in beliefs regarding males' and females' capacity to experience anger. Age of target differences were also found for sadness and anger, but not for happiness. It was concluded that preschoolers' beliefs about differences in emotions are complex, and vary as a function of the sex and age of the target person, and as a function of the specific emotion.Partial support for Richard Fabes was provided by a grant from the National Science Foundation (BNS-8807784). Partial support for Carol Martin was provided by a Women's Studies Research Award (CM1-1001) and a Faculty Grant in Aid (RWR-B658) from Arizona State University. The authors would like to thank Anita Petitti, Dennis Barrett, Amy Vogelson, Melinda Deacon, Kris Hughes, Amy Secklin, Hilary Rose, Melanie Smith, and Melinda Smith for their assistance with data collection and stimulus preparation. Thanks also goes to the teachers, staff, and children at the Arizona State University Child Laboratory Programs.     

The contribution of external and internal features to the matching of unfamiliar faces

The relative efficacy of external and internal features in matching unfamiliar faces was studied in three experiments in which the subjects matched target and test faces differing in terms of external or internal features, or both. In Experiment 1 only full congruency between target and test faces was considered a match; in Experiments 2 and 3 faces sharing the same external and internal features were also considered to be matches. A total of 100 subjects matched 192 pairs of target and test faces in a same-different task. Reaction times and matching errors were recorded for analyses of variance. In all three experiments performance was best when either all features matched or all features mismatched, with mismatches having a slight edge. When matches of external and internal features with the target faces were inconsistent with each other, mismatches of external features led to faster responses in Experiments 1 and 2, and mismatches of internal features led to faster responses in Experiment 3. The results suggest that since faces are configurational stimuli, face matching is influenced by the non-relevant set of features; and that mismatches, especially of external features, influence face matching more than matches do.     

Size of the attentional focus and efficiency of processing

By following Eriksen and St. James (1986) the experiments reported in this study focused upon three questions: (a) Can the spatial extent of the attentional focus be made to vary in response to precues? (b) As the area of the attentional focus increases, is there a decrease in processing efficiency for stimuli within the focus? (c) Is the boundary of the focus sharply demarked from the residual field or does it show a gradual dropoff? The results seem to provide answers to these questions: (a) the size of the attentional focus can be adjusted so that it covers areas of the visual field of different size; (b) there is a decrease in processing efficiency when the area of the attentional focus increases; and (c) there is a gradual dropoff in processing efficiency around the attentional focus.