When mechanistic models explain

Not all models are explanatory. Some models are data summaries. Some models sketch explanations but leave crucial details unspecified or hidden behind filler terms. Some models are used to conjecture a how-possibly explanation without regard to whether it is a how-actually explanation. I use the Hodgkin and Huxley model of the action potential to illustrate these ways that models can be useful without explaining. I then use the subsequent development of the explanation of the action potential to show what is required of an adequate mechanistic model. Mechanistic models are explanatory.     

Punishing Those Responsible for the Prison Abuses at Abu Ghraib: The Influence of the Negative Reciprocity Norm (NRN)

The negative reciprocity norm (NRN) is the personal moral code specifying retaliation as a proper response to wrongdoing ( Eisenberger, Lynch, Aselage, & Rohdieck, 2004 ). We examined the role of negative reciprocity in interpreting and reacting to the prison abuses at Abu Ghraib. Results showed that people who believed that American soldiers behaved wrongly at Abu Ghraib were more likely to view punishing the soldiers responsible as a highly moral response and were less likely to contribute money to a charitable organization that helps American soldiers. These relationships were only present among those highly endorsing the negative reciprocity norm.     

ON THE LIMITATIONS AND PROMISE OF QUANTUM THEORY FOR COMPREHENSION OF HUMAN KNOWLEDGE AND CONSCIOUSNESS

Abstract. I present a partially historical discussion of the basis of the quantum theory in nonmathematical terms using human knowledge and consciousness as an underlying theme. I show that the philosophical position in both classical and quantum theory is the experimental and mathematical philosophy of Isaac Newton. Because almost all the systems we deal with are multicomponent, we must consider the limitations and openness imposed by thermodynamics on our claims in both classical and quantum treatments. Here the reality of measurement stands in the way of any simple picture but also provides the basis for considerations of free will. Particular care is taken with the concepts of quantum measurement, entanglement, and decoherence because of their importance in the discussion.     

A diathesis-stress model of engagement in risky behaviors in Chinese adolescents

The current study examined whether the association between the occurrence of negative events and increased engagement in risky behavior is moderated by maladaptive and/or adaptive coping strategies. At time 1, 411 adolescents (ages 14–19) from Yue Yang, Hunan, completed self-report measures assessing coping strategies, engagement in risky behaviors, and the occurrence of negative events. Once a month for the subsequent 6 months, adolescents completed measures assessing engagement in risky behaviors and the occurrence of negative events. In line with our hypotheses, results of hierarchical linear modeling analyses indicated that adolescents possessing high levels of maladaptive coping strategies reported greater engagement in risky behaviors following the occurrence of negative events than adolescents possessing low levels. In contrast to our hypotheses, the association between the occurrence of negative events and increased engagement in risky behavior was not moderated by adaptive coping strategies.     

The psychosocial impact of Hurricane Katrina: contextual differences in psychological symptoms, social support, and discrimination

This study tested a contextual model of disaster reaction by examining regional differences in the psychosocial impact of Hurricane Katrina. A total of 386 individuals participated in this study. All were recruited in the primary areas affected by Hurricane Katrina and included residents of metropolitan New Orleans (Orleans Parish, Louisiana), Greater New Orleans (i.e., Metairie, Kenner, Gretna), and the Mississippi Gulf Coast (i.e., cities along the coast from Waveland to Ocean Springs, Mississippi). Participants were assessed for posttraumatic stress disorder (PTSD) symptoms, other psychological symptoms, perceptions of discrimination, perceptions of social support, evacuation distance, and the extent to which they experienced hurricane-related stressful events. Results were consistent with previous research on the impact of disasters on mental health symptoms. Findings extended research on individual differences in the response to trauma and indicated that regional context predicted unique variance in the experience of discrimination, social support, and emotional symptoms consistent with the theoretical model presented.     

Right-handers' reaching in contralateral hemispace: a kinematic observation

C. Gabbard and C. Helbig (2004) found, when examining seated participants' limb selection for reaching and grasping in hemispace, that right-handers preferred to switch to the nondominant left arm for objects located approximately 20 degrees horizontally from body midline (90 degrees) in left hemispace. In the present study, the authors examined 13 strongly lateralized seated right-handers' kinematics of reaching to object positions ranging from body midline to 40 degrees horizontally in left hemispace. Participants executed faster reaches with the left arm than with the right arm to objects placed 20 degrees-40 degrees from midline, whereas they did not change the proportion of time they spent accelerating the hands when the position of the object changed. A 2nd main finding was an increase in the left hand's trajectory curvature as object position moved farther from midline, with a corresponding decrease in the contribution of upper-arm motion to the reach. Those observations suggest that the switch from dominant right-arm reaching to nondominant left-arm reaching in left hemispace reported in the aforementioned study may have emerged from a shift from a shoulder-driven reach to an elbow-driven action.     

Update: new uses for lithium and anticonvulsants

Anticonvulsants are being used clinically as monotherapy and adjuncts in mental illnesses other than affective disorders. This review focuses on the literature for anticonvulsants and lithium in substance use disorders, anxiety disorders, and schizophrenia. Given the abuse potential and other difficulties with prescribing benzodiazepines for alcohol and benzodiazepine withdrawal, anticonvulsants have been considered as an alternative. Promising therapeutic effects have been demonstrated in many of the anxiety disorders, with the greatest number of trials and positive results in posttraumatic stress disorder. Although anticonvulsant and lithium augmentation for schizophrenia is common in practice and has been studied in double-blind, randomized, controlled trials, the sum of the evidence has been inconclusive.     

BEAUTY IN THE LIVING WORLD

Almost all admit that there is beauty in the natural world. Many suspect that such beauty is more than an adornment of nature. Few in our contemporary world suggest that this beauty is an empirical principle of the natural world itself and instead relegate beauty to the eye and mind of the beholder. Guided by theological and scientific insight, the authors propose that such exclusion is no longer tenable, at least in the data of modern biology and in our view of the natural world in general. More important, we believe an empirical aesthetics exists that can help guide experimental design and development of computational models in biology. Moreover, because theology and science can both contribute toward and equally profit from such an aesthetics, we propose that this empirical aesthetics provides the foundation for a living synergy between theology and science.     

Nach Möglichkeit leistungs- und genussfähig machen

“To make him [the patient] as efficient and as capable of enjoyment as is possible” (1923a, S.E. 18, p. 251) was, for Freud, a satisfactory definition of the treatment aims of psychoanalysis. The present paper connects this definition with the mythologically formulated antagonism between the drives in which Eros appears as the adversary of Thanatos, and elaborates this by drawing upon Plato’s notions about love as proposed in his “Symposion”. In doing this, the theory of Sublimation becomes the focus of attention quite naturally. It is the author’s thesis that this concept is more useful than that of a neutralized or even a primarily neutral ego-energy. This is more than a question of different opinions. It is the question of the usefulness of the genetic point of view and of the idea of the unity of the libido. Within the range of these concepts it is possible to elaborate in an adequate manner how we are capable to find satisfaction and fulfillment in achievements and enjoyment.