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Li Q Liu XS Zeng QW Xue QS Cao XH Liu J Ren Y Yu BW 《Neurobiology of learning and memory》2011,96(3):492-497
Considerable evidence indicates that the noradrenergic system of the basolateral amygdala (BLA) participates in the consolidation of various types of emotionally arousing memories. We previously reported that administration of an anesthetic-dose of sevoflurane immediately after continuous multiple-trail inhibition avoidance (CMIA) training impaired memory consolidation. This experiment investigated whether posttraining noradrenergic activation of the BLA is sufficient to reverse the memory impairing effect of sevoflurane. Adult male Sprague-Dawley rats received bilateral injections of norepinephrine (NE 0.3, 1.0, or 3.0 μg/0.5 μl) or normal saline (NS 0.5 μl) immediately after training in a CMIA paradigm. Subsequently, the rats were exposed to sevoflurane (2% inspired) or air for 2h. Norepinephrine produced a dose-dependent enhancement of memory consolidation on a 24-h retention test. The highest dose of NE tested (3.0 μg/0.5 μl) blocked sevoflurane-induced impairment of memory consolidation and reversed the inhibitory effect of sevoflurane on activity-regulated cytoskeletal protein (Arc) expression in the hippocampus 2h after training. These findings provide evidence that the mechanism mediating the memory-impairing effect of sevoflurane involves a network interaction between the BLA noradrenergic system and modulation of Arc protein expression in the hippocampus. 相似文献
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Jiang Jiang Yu Kou Fang Wang Ying Wu Yan‐Mei Li Yuan Li Yiyin Yang Hui Cao Qiuping Wu Shi‐Jie Jing Bi‐Jing Jiang La‐Mei Shen Ai‐Juan Li Zhongquan Li Wenjun Gao Chi‐Yue Chiu Ying‐Yi Hong Shih‐Chi Hsu Lin Zhang Bao‐Yan Yang Xiao‐Li Yang De‐Lei Zhao Zhimin Zou Qing‐Wang Wei Xia Chen Yu‐Fang Zhao Yi‐Jin Zhou Hong Chen Jianping Feng Xin Wang 《Asian Journal of Social Psychology》2011,14(3):207-216
A scandal can evoke public outrage when it is widely publicized and involves an individual who is perceived to have a high level of cultural representativeness. Two experiments showed that when the scandalous target's moral character was highlighted, emotional responses towards the target were least negative when the scandal was widely circulated and when the target was seen as a representative of his culture. These results suggest that when a cultural symbol is implicated in a widely‐circulated scandal, the negative emotions directed towards the scandalous individual can be alleviated when the public remains confident in his or her commitment to morality. 相似文献
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文章以遗传论、精神动力论、学习论、特质论、社会文化及认知一情感系统理论为基础。利用系统科学中的系统论观点,对人格理论进行系统发展观分析。该观点将人格看作一个复杂的“大”系统,它包括外部系统和内部系统两部分。外部系统即外环境系统,内部系统则分为个体心理系统和个体行为系统,其核心是个体心理系统,它由认识系统、情意系统、自我系统及需要系统构成。人格的形成是内外两个系统相互作用、循环运动的结果。 相似文献
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Beretta A Campbell C Carr TH Huang J Schmitt LM Christianson K Cao Y 《Brain and language》2003,85(1):67-92
The hypothesis that morphological processing is supported by a mental dictionary of stored entries plus a set of mental computations based on rules is examined using event-related fMRI. If a rules-plus-memory model () reflects the actual organization of the language faculty, two distinct patterns of brain activation should be observed for production of German irregular and regular noun and verb inflections. If a connectionist alternative to the rules-and-memory model (, and many others since), which seeks to explain the production of both irregular and regular forms within a single associative memory mechanism, is correct, there should be no neural differentiation between German regular and irregular inflection. The results we report support the existence of substantially differing patterns of activation for regulars vs. irregulars, an outcome that is consistent with the two-component rules-plus-memory account. 相似文献
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一、问题的提出 噪声对人体的危害,特别是直接对听力的危害,随着现代工业的迅速发展,已成为公害之一,越来越普遍地引起人们的极大关注。为了控制噪声和制定出可行的噪声允许标准,以期达到对人体的危害减少到最低的程度,多年来,国内外已做过不少的工作。 就人的听域而言,在一定的强度下,可听到的频率范围是很宽的。然而,就在现代化 相似文献
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Science and Engineering Ethics - Integrity and research ethics are cherished institutions in academic world. Although most societies have rules and codes that govern ethical conducts in research,... 相似文献