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91.
92.
Candice M. Chavez James L. McGaugh Norman M. Weinberger 《Neurobiology of learning and memory》2009,91(4):382-392
Stress hormones released by an experience can modulate memory strength via the basolateral amygdala, which in turn acts on sites of memory storage such as the cerebral cortex [McGaugh, J. L. (2004). The amygdala modulates the consolidation of memories of emotionally arousing experiences. Annual Review of Neuroscience, 27, 1–28]. Stimuli that acquire behavioral importance gain increased representation in the cortex. For example, learning shifts the tuning of neurons in the primary auditory cortex (A1) to the frequency of a conditioned stimulus (CS), and the greater the level of CS importance, the larger the area of representational gain [Weinberger, N. M. (2007). Associative representational plasticity in the auditory cortex: A synthesis of two disciplines. Learning & Memory, 14(1–2), 1–16]. The two lines of research suggest that BLA strengthening of memory might be accomplished in part by increasing the representation of an environmental stimulus. The present study investigated whether stimulation of the BLA can affect cortical memory representations. In male Sprague–Dawley rats studied under urethane general anesthesia, frequency receptive fields were obtained from A1 before and up to 75 min after the pairing of a tone with BLA stimulation (BLAstm: 100 trials, 400 ms, 100 Hz, 400 μA [±16.54]). Tone started before and continued after BLAstm. Group BLA/1.0 (n = 16) had a 1 s CS–BLAstm interval while Group BLA/1.6 (n = 5) has a 1.6 s interval. The BLA/1.0 group did develop specific tuning shifts toward and to the CS, which could change frequency tuning by as much as two octaves. Moreover, its shifts increased over time and were enduring, lasting 75 min. However, group BLA/1.6 did not develop tuning shifts, indicating that precise CS–BLAstm timing is important in the anesthetized animal. Further, training in the BLA/1.0 paradigm but stimulating outside of the BLA did not produce tuning shifts. These findings demonstrate that the BLA is capable of exerting highly specific, enduring, learning-related modifications of stimulus representation in the cerebral cortex. These findings suggest that the ability of the BLA to alter specific cortical representations may underlie, at least in part, the modulatory influence of BLA activity on strengthening long-term memory. 相似文献
93.
Miss Candice Renee Quinn 《Australian journal of psychology》2009,61(3):156-166
The current review provides a qualitative assessment of the efficacy of dialectical behaviour therapy (DBT) as adapted for adolescents. The aim was to assess the efficacy of DBT compared to usual methods in the treatment of adolescent mental health symptoms, inclusive of suicidal ideation and self‐harm. Computerised databases including Medline and PsycINFO were accessed and knowledgeable informants in the area of DBT were contacted. Inclusion criteria required the studies to be clinical trials on DBT provided to adolescents. Due to the requirements on research design only three studies were appropriate for review. The review focused on quality assessment of the current data, including investigation into the effects of selection bias, confounding variables, outcome measures and measurement errors. The data suggest that there is some evidence for DBT being effective in reducing symptoms of mental health, especially those consistent with borderline personality disorder. The resultant data, however, are of very poor quality, and as such the review addresses ways to improve the quality of research and offers suggestions for future research. 相似文献
94.
Lynn A. Rankin-Esquer Nancy Houston Miller Denise Myers C. Barr Taylor 《Journal of clinical psychology in medical settings》1997,4(4):417-435
The purpose of this study was to examine the relationship of marital status to health outcomes in 818 post-MI, coronary artery bypass surgery, and angioplasty patients (651 males, 157 females) from seven Northern California hospitals who completed 12 months of a nurse-managed, home-based multifactorial risk reduction program. Compared to married patients, nonmarried patients were significantly less likely to complete the program than married patients, more likely to smoke at baseline, and drank significantly less alcohol at baseline. At 12 months there were no significant differences between married and nonmarried groups on smoking cessation rates, HDL, LDL, triglycerides, or exercise treadmill test results. When patients were categorized as married, divorced, separated, widowed, or single, similar results were found for the analyses using two groups (married versus nonmarried), with the following exceptions. Separated patients were significantly less likely to quit smoking. In addition, separated patients showed significantly higher rates of starting (and continuing) to smoke during the time following their MI. Mortality was not significantly different between married and unmarried patients. Implications for intervention with separated patients and the importance of assessing both marital status and marital quality are discussed. 相似文献
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The purpose of this study was to examine gender differences in social network development from early to middle childhood and the relation of network characteristics to school competence. Maternal report of 75 children's kin, nonkin adult, and friendship networks were collected at 3, 6, and 9 years of age. Teacher ratings of school competence were obtained at 9 years. While children showed changes in their social networks over time, expected gender differences were not found in the extensive nature of the nonkin network. However, as expected, preference for same-sex friends was noted in early childhood and intensified with age into middle childhood. For girls, but not for boys, social network characteristics were related to teacher ratings of social competence in school.The preparation of this paper was made possible by the support of the William T. Grant Foundation. 相似文献
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The social networks of 85 young children as they make the transition from a home-centered to a more school-centered existence is examined using longitudinal data. When the children were three and six years of age, their mothers completed a questionnaire of network structure; at six years both the child and mother independently reported the friends that the child would invite to a birthday party. The effects of age and sex of child on the number and daily contact with peers, adults, kin, nonkin, males, and females were found. As expected, as children reached formal school age they had increased contact with peers and decreased contact with kin, while adult contact remained fairly consistent over the three- to six-year age period. Sex differences were also apparent. As predicted, children as early as 3 years, and to an even greater extent at six years, showed more same-sex compared to opposite-sex peer contact. At six years both children and mothers reported more same- as compared to opposite-sex friends who would be invited by the child to a birthday party. The findings suggest how children's social networks, as shaped by their parents and themselves, provide a framework within which experience and interaction is structured to fit cultural norms. 相似文献
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