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Wistar rats, treated with the GABA(A) receptor agonist muscimol, were used to investigate the role of the hippocampal-prelimbic cortical (Hip-PLC) circuit in spatial learning in the Morris water maze task, and in passive avoidance learning in the step-through task. In the water maze task, animals were trained for three consecutive days and tested 24 h after the end of training. In the step-through task, the animals were trained once and tested 24h after training. On the training days, daily infusion of muscimol (0.5 microg/0.25 microl) was given (1) bilaterally to the ventral hippocampus (vHip), (2) bilaterally to the prelimbic cortex (PLC), (3) to the unilateral vHip and the ipsilateral PLC, or (4) for disconnecting the Hip-PLC circuit, to both the unilateral vHip and the contralateral PLC 30 min before training. The results showed that inhibition of the vHip resulted in disruption of performance in both tasks. Inhibition of the PLC produced impaired water maze performance, but had no effect on the step-through task. Disconnection of the Hip-PLC circuit produced similar effects to PLC inhibition. However, simultaneous inhibition of the unilateral vHip and the ipsilateral PLC had little effect on performance of the water maze task. The results suggested that spatial learning depends on the Hip-PLC circuit, whereas passive avoidance learning is independent of this circuit. 相似文献
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中国区域经济发展中地方政府竞争的异质性 总被引:8,自引:0,他引:8
中国地区经济快速增长的事实证明,适度的地方政府竞争促进了中国地区经济发展和我国市场化进程,但中国现阶段的政治和经济体制安排使地方政府竞争存在异化的可能,严重的后果是导致形成“蜂窝状经济”。解决地方政府竞争异化问题,关键不是否定地方政府竞争的积极作用,更不是要消除地方政府间的竞争,而是解决地方政府产生异化的制度条件,引导地方政府行为在一个合理的、法制化的框架内充分、积极的发挥作用。 相似文献
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童年中期同伴关系、同伴关系知觉与心理行为适应的关系 总被引:2,自引:0,他引:2
本研究以422名小学二、三、四年级的儿童进行为期3年的纵向研究,考察了时间2的同伴关系知觉在时间1的同伴关系和时间3的心理行为适应之间的中介效应。结果表明,自我知觉的社会能力在同伴接纳与社交/领导行为和孤独感之间的中介作用显著,自我知觉的友谊质量在双向互选朋友与社交/领导行为和孤独感之间的中介作用显著。 相似文献
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儿童语言获得之认知发展机制研究新进展 总被引:1,自引:0,他引:1
儿童母语的习得是以已有的知识经验为基础的,即概念信息,由此儿童可以对经验过的对象、关系和事件做出区分并加以归类。这为以后儿童语言的获得奠定了基础。因此,儿童首先建立的是对事物的概念性表征,然后再以语言的形式表达之,即获得了语言性表征。但是,当儿童获得了语言表征之后,原先的概念表征还是继续发挥着它应有的作用。 相似文献
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在社会智力研究的早期,研究者们运用测量观的视角和方法对社会智力进行了研究,取得了不少的成果。但是随着研究的进行,传统测量观的发展却遇到了极大的困难,如不能对社会智力和学业智力进行有效的区分等。人格的社会智力观强调社会行为的背景具体化和行为的主观意义,主张探询人的一般化的社会认知机制,为社会智力的研究展开了一个新的视角。 相似文献
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Environmental enrichment improves behavioral performance and auditory spatial representation of primary auditory cortical neurons in rat 总被引:1,自引:0,他引:1
Rui Cai Fei Guo Jiping Zhang Jinghong Xu Yilei Cui Xinde Sun 《Neurobiology of learning and memory》2009,91(4):366-376
Environmental enrichment (EE) has an important role in brain plasticity. Early research has shown that EE increases the response strength of neurons in the auditory cortex, but it remains unknown whether EE can influence the process of spatial localization in the auditory system. In this study, we raised rats in enriched and standard conditions from postnatal day 10 to day 56. By testing behavioral tasks via auditory cues, we have shown that EE improved the number of correct scores, but decreased the reaction time and azimuth deviation in behavioral performance of sound-azimuth discrimination. By in vivo extracellular recording, we have shown that EE enhanced the directional sensitivity of neurons in the primary auditory cortex. For example, EE rats had a smaller spatial receptive field, sharper frequency tuning curve and directional selective curve of auditory neurons compared with normal rats. Our findings indicate that early exposure to EE increases directional sensitivity. These results provide an insight into developmental plasticity in the auditory system. 相似文献
59.
In a provocative article, Heine et al. concluded that self-esteem needs are less important in collectivistic, East Asian countries than in individualistic, Western ones. Their conclusion was based, in part, on evidence that: (i) self-esteem scores are less positively biased in Japan than in Western countries; and that (ii) low self-esteem is less predictive of psychological distress in Japan than in Western countries. The present research examined whether these cultural differences occur in another collectivistic culture: The People's Republic of China. Two meta-analyses were conducted. Study 1 found that, for young and old alike, self-esteem was positively biased, with most participants reporting high levels of self-esteem. Study 2 found that low self-esteem in China is associated with three indicators of psychological distress: depression, anxiety and low subjective well-being. These findings are consistent with results in Western samples and suggest that high self-esteem may indeed be a universal psychological imperative. 相似文献
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