Validity and reliability of electroencephalographic frontal alpha asymmetry and frontal midline theta as biomarkers for depression

Electroencephalographic (EEG) frontal alpha asymmetry (FAA) and frontal midline (FM) theta have been suggested as biomarkers for depression and anxiety, but have mostly been assessed in small and non‐clinical studies. In a clinical sample of 79 adults with depression (ICD‐10: F32), resting EEG and scales of depression (MADRS) and anxiety (HADS‐A) were measured at intake and after 3 months. FAA and FM theta values were referenced to a normative population database. Internal consistency, test‐retest reliability, and correlations with psychiatric tests were examined. Reliability was sufficient. However, FAA and FM theta values were close to the general population, and correlations with psychiatric tests were mostly small and non‐significant, with the exception of FAA on F7–F8 z‐scores and HADS‐A. We conclude that the validity of FAA and FM theta and therefore their potential as biomarkers for depression and anxiety remain unclear.     

Sibling loss, guilt and reparation: A case study

Psychoanalysis has shown that the death of a sibling is likely to have a long-standing impact on the character development of a surviving child. Among common adult manifestations are the identifi cation with the deceased sibling, repetitive self-punitive behaviors, and the development of masochistic trends. In treatment, these patients can become entrenched in a negative therapeutic reaction that compromises the outcome of their analysis. In this paper, the author discusses the analysis of a woman with a history of losses that included the loss of a sibling at an early age. A critical part of the treatment focused on helping this patient overcome a negative therapeutic reaction that emerged as she became aware of hostile and vengeful fantasies, not only as they related to her deceased brother but, more importantly, as they related to her parents.     

“I know you're kidding”: Relationship closeness enhances positive perceptions of teasing

Feeling close in a relationship may enhance perceptions of teasing within that relationship. In Study 1, participants recalled instances of teasing—as both teaser and target—in close and nonclose relationships. Participants perceived teases in close relationships more positively and better intentioned than those in nonclose relationships, as both teaser and target. The discrepancy between teasers and targets in perceptions of intent was also reduced by felt closeness. In Study 2, interaction partner closeness was manipulated and a tease was staged. Teases delivered by a close (vs. nonclose) partner were perceived as more positive and better intentioned. Each study has limitations but their methods complement each other. Together they provide convergent evidence that relationship closeness increases positive perceptions of teasing.