替格瑞洛与氯吡格雷对急性STEMI患者急诊PCI术后炎症因子的影响

为比较替格瑞洛与氯吡格雷对急性ST段抬高型心肌梗死（STEMI）患者急诊经皮冠状动脉介入术（PCI）术后炎症因子的影响,将176例急性STEMI且行急诊PCI术的患者分为替格瑞洛组（A组）58例、氯吡格雷常规组（B组）58例、氯吡格雷强化组（C组）60例,分别测定术前、术后12小时、术后7天、术后1个月、术后3个月、6个月时炎症因子e反应蛋白（CRP）、白细胞介素-6（IL6）、髓过氧物酶（MPO）、可溶性CD40受体（sCD40L）的含量,比较3组患者各炎症因子在不同时间点有无统计学差异。结果显示c组和A组较B组明显降低（P〈0．05）,有统计学意义,而A组较c组稍降低（P〉0．05）,但两者无统计学意义。由此可见,替格瑞洛的抗炎作用较常规剂量氯吡格雷作用明显增强,和强化剂量氯吡格雷作用相仿。     

多级评分模型下的题库结构对CAT的影响分析

在多级评分模型下,项目的难度参数或步骤参数有多个,在对多级评分模型进行选题时,通常对项目的多个难度参数用一个综合的指标来概括.当对每个项目的难度参数进行有效的综合后,综合后的难度参数分布发生了改变,这时如果增加适量的平均难度较难或较易的项目进入题库,测验的精度和项目的曝光率都有一定的改善.     

The Mystery of Chinese People’s Happiness

The great improvement in economic wealth and social welfare over the decade doesn’t promote the Chinese people’s happiness. We construct a theoretical framework which covers economic wealth, social welfare, individual functional capability to explore the impact factors and determinants of the Chinese people’s happiness. Based on a national wide questionnaire survey in China, we test and modify the framework by the method of structural equation model. The empirical findings indicate that there are direct and indirect effects on the formation of happiness. For the direct effect, both the increasing of economic wealth and social welfare improves the national happiness, while the individual functional capability reduces it. For the indirect effect, the individual functional capability also reduces happiness by negatively affecting economic wealth and social welfare. The negative effect that played by individual functional capability overwhelms the positive effect played by economic wealth and social welfare. This causes the Chinese people’s happiness goes down while the economic wealth and social welfare are improving. Finally, we conclude that the Chinese people’s happiness is more about individual functional capability rather than social welfare or economic wealth.     

同事个性化契约对员工工作退缩行为的影响:基于公平理论的视角

个性化契约作为组织中一种非标准化的工作安排,以往研究较多关注其对契约获得者的积极效应,相对忽视了对未获得者的消极影响。鉴于此,本研究基于公平理论,探讨了同事个性化契约对员工工作退缩行为的影响及其内部机理。结果发现:同事个性化契约会引发员工的工作退缩行为,员工的心理契约违背在此过程中起部分中介作用;此外,员工与组织间较高的社会交换关系会削弱同事个性化契约对员工心理契约违背的正向影响。     

Associations between childhood biomedical factors,maternal smoking,personality traits,Body and Mass Index and the prevalence of asthma in adulthood

Objective: The study set out to investigate socio-economic, biomedical, health and behavioural and psychological factors in childhood and adulthood associated with the prevalence of asthma in adulthood, drawing data from The National Child Development Studies (NCDS), a birth cohort in the UK.

Design: The National Child Development Study, a nationally representative sample of 17,415 babies born in Great Britain in 1958 and followed up at 7, 11, 33 and 50 years was used.

Main Outcome Measure: The prevalence of asthma at age 50 was the outcome measure. The analytic sample consists of 5118 participants with complete data on a set of measures at birth, at ages 7, 11, 33 and 50 years.

Results: Using logistic regression analyses, results showed that childhood asthma (OR = 6.77: 4.38–10.48, p < .001) and respiratory symptoms (OR = 1.83: 1.18–2.86, p < .01), maternal smoking during pregnancy (OR = 1.26: 1.00–1.59, p < .05), Body and Mass Index (BMI) (OR = 1.03: 1.02–1.05, p < .001), traits Neuroticism (OR = 1.13: 1.01–1.21, p < .05) and Conscientiousness (OR = 0.76: 0.76–0.96, p < .01), as well as sex (OR = 1.49: 1.15–1.94, p < .001) were all significantly associated with the prevalence of asthma in adulthood.

Conclusion: The study shows that both childhood and adulthood psychological and sociological factors are significantly associated with the prevalence of asthma in adulthood, though more work need to be done in this area.     

教师支持与心理素质对中学生学业成绩的影响

采用学生感知教师支持行为问卷和中学生心理素质问卷,对西南地区两所中学7~12年级的824名在校中学生进行调查研究,探讨教师整体支持和不同类型支持与中学生学业成绩的关系及心理素质在其中的中介作用。结果发现：（1）教师整体支持与中学生心理素质、学业成绩间存在显著正相关;教师情感支持与中学生心理素质、学业成绩间存在显著正相关,教师学习支持、能力支持与中学生心理素质存在显著正相关,但与学业成绩相关均不显著;（2）控制性别和年龄后,心理素质在教师整体支持与学业成绩的关系中起完全中介作用;心理素质在教师情感支持与学业成绩关系中起部分中介作用,在教师学习支持与学业成绩、教师能力支持与学业成绩关系中均起完全中介作用。     

Associations between Race and Eating Disorder Symptom Trajectories in Black and White Girls

Epidemiological research suggests racial differences in the presentation of eating disorder symptoms. However, no studies have examined associations between race and eating disorder symptom trajectories across youth and adolescence, which is necessary to inform culturally sensitive prevention programs. The purpose of the current study was to examine the trajectories of eating disorder symptoms from childhood to young adulthood and to examine whether race was associated with trajectory group membership. Data were drawn from 2,305 Black and White girls who participated in a community-based longitudinal cohort study (Pittsburgh Girls Study) examining the development of psychopathology. The child and adult versions of the Eating Attitudes Test assessed self-reported eating disorder symptoms at six time points between ages 9 and 21 years. Growth mixture modeling was used to examine developmental trajectories of dieting, bulimia/food preoccupation, and total eating disorder symptom scores. Given potential confounds with race and disordered eating, financial strain (i.e., receiving public assistance) and weight were included as covariates. Four to six distinct developmental patterns were found across eating disorder symptoms, including none, increasing, decreasing, or increasing-decreasing trajectories. Black girls had a greater likelihood of being in the decreasing trajectories for dieting, bulimia/food preoccupation, and total eating disorder symptom scores. White girls were more likely to follow increasing trajectories of dieting and total eating disorder symptom scores compared to Black girls. These results highlight the importance of examining the influence of racial background on eating disorder symptoms and the potential need for differences in the timing and focus of prevention interventions in these groups.     

Autonomic conditioning to monetary and social stimuli and aggression in children

Poor conditioning to punishment, such as loud tones or electric shock, has been proposed as an important factor involved in the etiology of aggressive and psychopathic behavior. However, it is not known whether the association holds when monetary or social stimulus is used as the unconditioned stimulus, and if aggressive individuals also have impaired conditioning to rewards. In this study, skin conductance responses in a conditioning task involving both monetary/social reward and punishment as unconditioned stimuli were assessed in 340 male and female 8‐ to 9‐year‐old children from the community. Children reported their reactive and proactive aggression using the Reactive and Proactive Aggression Questionnaire (RPQ; Raine et al., 2006). Results showed that monetary/social reward and punishment were effective in eliciting physiological classical conditioning in children, and that reduced reward conditioning was associated with high levels of proactive aggression in particular. Findings highlight the importance of distinguishing between reactive and proactive aggression when examining antisocial behavior in children, and suggest that reward‐oriented treatment programs may not be effective for children with more proactive, instrumental aggressive behavior.

     

Quine's Naturalism and Behaviorisms

This paper investigates the complicated relations between various versions of naturalism, behaviorism, and mentalism within the framework of W. V. O. Quine's thinking. It begins with Roger Gibson's reconstruction of Quine's behaviorisms and argues that it lacks a crucial ontological element and misconstrues the relation between philosophy and science. After getting clear of Quine's naturalism, the paper distinguishes between evidential, methodological, and ontological behaviorisms. The evidential and methodological versions are often conflated, but they need to be clearly distinguished in order to see whether Quine's argument against mentalism is cogent. The paper argues that Quine's naturalism supports only the weakest version of behaviorism, that is, the evidential one, but this version is compatible with mentalistic semantics. Quine's opposition to mentalism is an overreaction against the behaviorist camp. By contrast, Jerry Fodor's objection to José Luis Bermúdez is an overreaction from the opposite direction.