Receiver operating characteristics for the brief symptom inventory depression, paranoid ideation, and psychoticism scales in a large sample of clinical inpatients

A commonly used screening tool for psychopathology, the Brief Symptom Inventory, provides normative data for assessing current mental functioning across multiple domains. Using data from 654 psychiatric inpatients, receiver operating characteristic (ROC) analyses were conducted for three scales, Depression, Paranoid Ideation, and Psychoticism. t ratios identified significant group differences on the Depression scale between patients diagnosed with or without depression but no differences on the Paranoid Ideation and Psychoticism scales between patients diagnosed with or without schizophrenia. Area under the curve for Depression was .65, indicating that the scale improved diagnostic prediction somewhat beyond chance; for Paranoid Ideation, the area was .52 and for Psychoticism, the area was .53, indicating that these two scales did not significantly improve diagnostic prediction beyond chance.     

科学对“后世”声称的检验（一）

后世存在有证据吗？我们能否与亡者进行沟通？他们的存在是否具有一定的形式呢？是“脱离肉体的灵魂”或是“无实体的精神”？这是个古老的问题,它事关信仰永生和强烈的对不朽的渴望。科学能否调查和揭示那些基于有神论信仰者利益的声明吗？回答是肯定的。科学在尽其所能来回应这些声称时要面对不仅仅是宗教学家们所倡导的灵魂不朽和天堂许诺等内容对人们的深刻影响,还要迎接来自媒体和公众的艰巨的挑战,媒体不断追求轰动效应,庞大的公众群体迷恋于此类现象。     

Clinical Audit and Reform of the UK Research Ethics Review System

There is an international consensus that medical research involving humans should only be undertaken in accordance with ethical principles. Paradoxically though, there is no consensus over the kinds of activities that constitute research and should be subject to review. In the UK and elsewhere, research requiring review is distinguished from clinical audit. Unfortunately the two activities are not always easy to differentiate from one another. Moreover, as the volume of audit increases and becomes more formal in response to the demand for evidence-based practice in medicine, the overlap between research and audit grows more acute. Arguably, similar ethical standards and systems for ensuring that those standards are met should be applied regardless of whether or not a project is classified as research or audit. At a time when the research ethics review system in the UK is undergoing significant reform it is important that the opportunity is not missed to address the longstanding research-audit problem. We discuss suggestions for further reform that addresses this issue.     

Contextual specificity of extinction of delay but not trace eyeblink conditioning in humans

Renewal of an extinguished conditioned response has been demonstrated in humans and in animals using various types of procedures, except renewal of motor learning such as eyeblink conditioning. We tested renewal of delay and trace eyeblink conditioning in a virtual environment in an ABA design. Following acquisition in one context (A, e.g., an airport) and extinction in a different context (B, e.g., a city), tests for renewal took place in the acquisition (A) and extinction context (B), in a counterbalanced order. Results showed renewal of the extinguished conditioned response in the delay but not trace condition.     

Life events as predictors of mania and depression in bipolar I disorder

To date, few prospective studies of life events and bipolar disorder are available, and even fewer have separately examined the role of life events in depression and mania. The goal of this study was to prospectively examine the role of negative and goal-attainment life events as predictors of the course of bipolar disorder. One hundred twenty-five individuals with bipolar I disorder were interviewed monthly for an average of 27 months. Negative and goal-attainment life events were assessed with the Life Events and Difficulties Schedule. Changes in symptoms were evaluated using the Modified Hamilton Rating Scale for Depression and the Bech-Rafaelsen Mania Scale. The clearest results were obtained for goal-attainment life events, which predicted increases in manic symptoms over time. Negative life events predicted increases in depressive symptoms within regression models but were not predictive within multilevel modeling of changes in depressive symptoms. Given different patterns for goal attainment and negative life events, it appears important to consider specific forms of life events in models of bipolar disorder.     

Is there evidence for the use of art therapy in treatment of psychosomatic disorders,eating disorders and crisis? A comparative study of two different systems for evaluation

A comparative study of two different systems for evaluation. Scandinavian Journal of Psychology 53, 47-53. As with any type of treatment the requirement for evidence based practice (EBP) has also affected art therapy (AT) when used as an intervention. This review evaluates the available evidence for using AT for psychosomatic disorders, eating disorders and crisis. The search in Cochrane, Best Practice, AMED, CINAHL, PION, PsycINFO and PubMed from 1987 until now resulted in a huge number of articles but only 32 articles met our criteria for evaluations. The articles were assessed with two evaluation systems, the GRADE system used by the Swedish Council on Health Technology Assessment (SBU) and the US Preventive Services Task Force (USPSTF/Task Force). When comparing the results we found that the GRADE evaluation system rejected the quality in 84% of the 32 studies and the USPSTF/Task Force 41% of these studies. An evidence base for AT was found only according to the criteria of USPSTF/Task Force. Hence, the evidence concept is not explicit, which means that effective treatments run a risk of not being implemented in health care. We suggest a broader view of what constitutes evidence in order to make it possible to include different types of research designs and methods.     

罗蒂的实用主义

许多人主张,R.罗蒂是在传统哲学的范围中进行论证的,尽管他的论点恰恰相反。本文的目的,就是针对这些人的看法提出一个建议:应把罗蒂看作是处于哲学传统之外的重要思想家,一个处于哲学传统之外的批判者。我的建议所围绕的中心,是略述罗蒂的实用主义如何不同于人们较为熟知的那些实用主义。一般承认,实用主义是一种重要的哲学观点,一种经常被援引的观点。但难得有人对这一观点作出清楚的说明。这是由于,当人们援引实用主义时,往往把它与包含有真理符合论的主张和观点加以对比,因而只是对它作了颇为有限的论述。最近罗蒂以几种方式援引了实用主义。通过这些方式,他驳斥了真理符合论,甚至一般地驳斥了需要有任何真理理论,他诉诸实用主义,运用成效     

Choice, time allocation, and response rate during stimulus generalization

Six pigeons were trained to discriminate between two noise intensities using a procedure that assessed choice, time allocation, and response rate simultaneously and independently. Responses on the left or right key (R1 or R2) were respectively correct in the presence of two different intensities, S1 and S2. After a correct response, reinforcement became available for pecks on the center key. Reinforcement density for R1¦S1 relative to R2¦S2 was varied across experimental conditions. Generalization tests followed extensive training at each condition. As a function of stimulus intensity, proportions of initial choices of R2, of time spent in R2-initiated components, and of center-key responses emitted in R2-initiated components all yielded sigmoidal gradients of similar slope, which shifted slightly in location when relative reinforcement density changed. Changeovers were maximal where initial choice proportions approximated 0.5. Gradients relating the absolute number of center-key responses to stimulus intensity were also roughly sigmoidal, but were more sensitive to changes in reinforcement density. Gradients of momentary response rate also depended on reinforcement density. During training, large but transitory shifts in choice responding occurred when reinforcement density changed, while differences in momentary response rate developed slowly, suggesting separate control of choice and response rate by the contingencies of reinforcement.     

环境伦理学

一、导论面对“环境危机”,环境哲学家们有一种相当普遍的共识,即应该从伦理学的角度来考察环境问题。他们一致认为,环境问题是重要的,但它在过去没有得到足够的重视。同样,他们也一致认为,在我们处理环境问题时,伦理学应起到更大的作用。然而,也有不一致的地方,即环境伦理学是由什么组成的,怎样才能实现它,在什么程度上实现它是理想的。本文考察当个环境伦理学的关键问题。价值观和对环境及为环境所采取的行动深深地被我们对环境的观察与理解影响着。因此,本文一开始叙述了在过去的一个世纪里,在环境问题上,科学对环境问题的…