Research & clinical exchange

Abstract

Question: Family therapists are often called upon to do consultations to schools about children having social and educational difficulties. In what ways is the family therapist's role different when he or she is called in to consult as an “outsider’ to the school system about a particular child whom he or she does not know, compared to being called upon by the school for advice about a child who is already being seen in treatment by that therapist?     

Relationship between religious characteristics and responses to vigilantism

Religious characteristics are often related to attitudes about legal issues (e.g., death penalty). This study investigated whether U.S. university students’ religious beliefs (i.e., fundamentalism, devotionalism, evangelism) and religious motivations (i.e., intrinsic, extrinsic religiosity) were associated with responses to vigilantism (i.e., whether the vigilante is justified, should be legally responsible, should receive a lighter sentence). Participants read three scenarios describing vigilantism in response to different crimes (murder, drug dealing, child molestation). More punitive responses to vigilantism were associated with being low in fundamentalism, extrinsic religiosity, and evangelism, and with being high in devotionalism and intrinsic religiosity. Motivations were more frequent predictors of responses to vigilantism than beliefs. Results are the first step in explaining relationships between religious characteristics and responses to vigilantism.     

Inhibitory effects of drinker and nondrinker prototypes on adolescent alcohol consumption.

This prospective study examined the relation between 308 adolescents' images of typical dinkers and nondrinkers and their subsequent alcohol consumption. The results indicate that both images are associated with changes in consumption between ages 16 and 18 but that they operate in different ways. Contrary to previous assumptions, drinker images do not represent goal states for adolescents in that they are more negative than their self-images and nondrinker images and are not correlated with their ideal selves. In contrast, nondrinker images do appear to represent goal states for adolescents who abstain from drinking. Implications for intervention are discussed.     

Exploring the Association between Aggression and Anxiety in Youth: A Look at Aggressive Subtypes,Gender, and Social Cognition

We examined the associations among dimensions of aggression and anxiety disorder symptoms in an ethnically diverse community sample of youth (N = 83; 46% female). Research supports the existence of four aggressive subtypes (i.e., reactive overt, reactive relational, proactive overt, and proactive relational), and past research has found associations between relational aggression and anxiety, as well as between reactive aggression and anxiety. However, past studies have not examined the associations among anxiety symptoms and the combined subtypes of aggression mentioned above. Results of our study provided support for an association between anxiety and reactive relational aggression. In addition, gender was found to moderate the association, in that males with high anxiety showed higher levels of reactive relational aggression than males with low anxiety and girls. Further, we found that socially based negative cognitive errors mediated the association between reactive relational aggression and anxiety. Results are discussed in terms of clarifying gender differences in aggression, treatment implications, and the need for longitudinal studies to delineate the temporal associations between aggression and anxiety.     

Different involvement of type 1, 2, and 3 ryanodine receptors in memory processes

The administration of the ryanodine receptor (RyR) agonist 4-Cmc (0.003-9 nmol per mouse intracerebroventricularly [i.c.v.]) ameliorated memory functions, whereas the RyR antagonist ryanodine (0.0001-1 nmol per mouse i.c.v.) induced amnesia in the mouse passive avoidance test. The role of the type 1, 2, and 3 RyR isoforms in memory processes was then evaluated by inhibiting the expression of the three RyR proteins in the mouse brain. A selective knockdown of the RyR isoforms was obtained by the i.c.v. administration of antisense oligonucleotides (aODNs) complementary to the sequence of RyR1, RyR2 and RyR3 proteins, as demonstrated by immunoblotting experiments. RyR1 (5-9 nmol per mouse i.c.v.) knockdown mice did not show any memory dysfunction. Conversely, RyR2 (1-7 nmol per mouse i.c.v.) and RyR3 (1-7 nmol per mouse i.c.v.) knockdown animals showed an impairment of memory processes. This detrimental effect was temporary and reversible, disappearing 7 d after the end of the aODN treatment. At the highest effective doses, none of the compounds used impaired motor coordination, as revealed by the rota rod test, nor modified spontaneous mobility and inspection activity, as revealed by the hole-board test. In conclusion, the lack of any involvement of cerebral RyR1 was demonstrated. These findings also showed the involvement of type 2 and type 3 RyR in the modulation of memory functions identifying these cerebral RyR isoforms as critical targets underlying memory processes.     

Mice with targeted genetic reduction of GABA(A) receptor alpha1 subunits display performance differences in Morris water maze tasks

Recent research has begun to demonstrate that specific subunits of GABA(A) receptors may be involved in the normal expression of specific behaviors. The present research used mice with GABA(A) receptors whose alpha1 subunits contained mutations of serine 270 to histidine and leucine 277 to alanine in the TM2 region. The purpose was an attempt to examine the possible role that this particular subunit may have in learning the spatial and nonspatial version of the Morris water maze task. Mutant animals, compared to controls, displayed elevated levels of pool circling in both the spatial task and the nonspatial task. These results suggested that normal performance of the spatial and nonspatial water maze tasks may be dependent upon a natural alpha1 subunit array.     

The use of aftereffects in the study of relationships among emotion categories

The perception of visual aftereffects has been long recognized, and these aftereffects reveal a relationship between perceptual categories. Thus, emotional expression aftereffects can be used to map the categorical relationships among emotion percepts. One might expect a symmetric relationship among categories, but an evolutionary, functional perspective predicts an asymmetrical relationship. In a series of 7 experiments, the authors tested these predictions. Participants fixated on a facial expression, then briefly viewed a neutral expression, then reported the apparent facial expression of the 2nd image. Experiment 1 revealed that happy and sad are opposites of one another; each evokes the other as an aftereffect. The 2nd and 3rd experiments reveal that fixating on any negative emotions yields an aftereffect perceived as happy, whereas fixating on a happy face results in the perception of a sad aftereffect. This suggests an asymmetric relationship among categories. Experiments 4-7 explored the mechanism driving this effect. The evolutionary and functional explanations for the category asymmetry are discussed.