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191.
The DRD4 VNTR polymorphism moderates craving after alcohol consumption. 总被引:11,自引:0,他引:11
Kent E Hutchison John McGeary Andrew Smolen Angela Bryan Robert M Swift 《Health psychology》2002,21(2):139-146
Recent research has suggested that alterations in mesolimbic dopamine neurotransmission are central to the development and expression of craving for alcohol. Because the D4 dopamine receptor gene, variable numbers of tandem repeats (DRD4 VNTR) polymorphism putatively expresses functional differences in dopamine receptors, the present study tested whether this polymorphism influences the effects of a priming dose of alcohol on craving. Participants consumed 3 alcoholic drinks or 3 control drinks and completed measures of craving after each drink. Participants who were homozygous or heterozygous for the 7 (or longer) repeat allele were classified as DRD4 L, whereas the other participants were classified as DRD4 S. Results suggested that DRD4 L participants demonstrated significantly higher craving after consumption of alcohol as compared with the control beverage. 相似文献
192.
193.
Bryan S. K. Kim Gladys F. Ng Annie J. Ahn 《Journal of counseling and development : JCD》2009,87(2):131-142
Based on data from 61 Asian American clients at a university counseling center, the study found that client‐perceived match on client‐counselor belief about problem etiology was related to counselor credibility, empathy, and cross‐cultural competence; the client‐counselor working alliance; session depth; and the likelihood of the client recommending the counselor to another client. An interaction effect showed that both strong match on belief about problem etiology and high client expectation for counseling success were associated with strong client‐counselor working alliance. 相似文献
194.
Bryan Hall 《British Journal for the History of Philosophy》2013,21(1):79-109
This paper poses a dilemma for applying the category of substance given Kant's different conceptions of substance in the Critique of Pure Reason. Briefly stated, if the category of substance applies to an omnipresent and sempiternal substance, then although this would ensure that all experiences of empirical objects take place in a common spatiotemporal framework, one could not individuate these empirical objects and experience their alterations. If the category of substance applies to ordinary empirical objects, however, then although one could individuate these substances and experience their alterations, the category would not pick out a common spatiotemporal framework for these experiences. I will argue that this dilemma can be overcome by examining the development of Kant's conception of substance in his final work, the Opus postumum. 相似文献
195.
196.
Sex Roles - Information was obtained from 184 females and 157 males enrolled in grade 11 in six urban high schools. The majority of the students were of European descent (70%), but there were... 相似文献
197.
The person-by-situation interaction model of anxiety was tested in the reallife setting of an academic examination. Twenty-eight male and 79 female university students served as subjects. State anxiety (A-State) was assessed just prior to the examination (Trial 2) and approximately 1 week before (Trial 1) and after (Trial 3) the examination. Five facets of trait anxiety (A-Trait) were measured in a nonstressful situation 1 week prior to the examination. The subject's cognitive appraisal of the various situations was assessed by a self-report index of the type and degree of threat involved in the situation just experienced. As predicted, a significant A-Trait-by-situation interaction in eliciting A-State was observed for social evaluation A-Trait. There were no interactions for the other, noncongruent facets of trait anxiety. The results also indicated that individuals' perception of situations may be the most important factor affecting reactions to stressful situations. In general, the results were interpreted as providing support for the multidimensionality of A-Trait and further validation of the interaction model of anxiety. 相似文献
198.
Philosophical Studies - 相似文献
199.
Bryan Pfaffenberger 《Knowledge, Technology, and Policy》1999,12(3):94-112
Imagine if each square of pavement on the sidewalk had an owner, and pedestrians required a license to step on it. Imagine
the negotiations necessary to walk an entire block under this system. That is what writing a program will be like if software
patents continue. The sparks of creativity and individualism that have driven the computer revolution will be snuffed out.
Imagine if each square of pavement on the sidewalk had an owner, and pedestrians required a license to step on it. Imagine
the negotiations necessary to walk an entire block under this system. That is what writing a program will be like if software
patents continue. The sparks of creativity and individualism that have driven the computer revolution will be snuffed out.—Richard
Stallman and Simson Garfinkel (1992)
This article highlights the vulnerability of the open source software movement to patent infringement lawsuits. With the number
of patents on software algorithms predicted to exceed 100,000 this year, it is now virtually impossible to write any computer
program, however trivial, that does not violate one or more patents. This paper argues that this situation is not only ludicrous,
but it is contrary to any reasonable reading of the Constitution’s intentions with respect to the protection of intellectual
property. In addition, the patentability of software algorithms stems from the U.S. Supreme Court’s failure to grasp one of
the most fundamental concepts of computer science. From this error stems a long, dysfunctional chain of legal reasoning and
patent policies, the effect of which has been to transform the mental reasoning processes, abstract knowledge, and scientific
truths of computing into patentable subject matter. The result poses a potentially catastrophic threat not only to the open
source software movement and the emerging industry of electronic commerce, but more fundamentally, to the very existence of
the sciences of computing, without which further U.S. technological leadership will be impossible to sustain.
An anthropologist, Dr. Pfaffenberger has authored dozens of how-to and reference books on computers and the Internet. He won
the Albert Payson Usher Prize from the Society for the History of Technology and the Best Book of the Year Award from the
American Society for Information Science. 相似文献
200.
Selective attention and the processing of integral and nonintegral dimensions: A developmental study
In two experiments, first- and fourth-grade subjects (age 6 and 9 years) performed a speeded card-sorting task with either integral or nonintegral dimensions. The dimensions were so arranged that subjects sorted on three types of task: (1) single dimension, (2) correlated dimensions, and (3) orthogonal dimensions. Results of the first experiment indicate that both first- and fourth-grade subjects sorted integral dimensions in a manner not qualitatively different from that of the adult (Garner & Felfoldy, Cognitive Psychology, 1970, 1, 225–241). In comparison with single-dimension tasks, performance was facilitated on the correlated-dimensions tasks and interference was observed on the orthogonal-dimensions tasks. Performances with nonintegral dimensions revealed an age-related processing difference. Fourth graders sorted nonintegral dimensions like the adult; no differences in performance were observed between the tasks. In contrast, first-graders sorted nonintegral dimensions as if they were integral. Interference was consistently observed on orthogonal-dimensions tasks. On correlated-dimensions tasks, interference was observed on easy tasks and redundancy facilitated difficult tasks. In the second experiment, first graders showed consistent facilitation on the correlated-dimensions task; all other results were indentical to those of Experiment I. The results were interpreted as consistent with perceptual learning theory (Gibson, Principles of perceptual learning and development. New York: Appleton-Century-Crofts, 1969). 相似文献