口腔颌面部鳞状细胞癌的综合序列治疗

口腔颌面部鳞状细胞癌(鳞癌)在头颈部肿瘤的发病和治疗中占有重要地位,综合序列治疗的概念和理论逐渐成为口腔颌面部鳞癌治疗的指导原则.本文对口腔颌面部鳞癌综合序列治疗所包含的手术治疗、放射治疗、化学治疗及生物治疗从临床治疗策略上进行分析、讨论,以期促进口腔颌面部鳞癌综合序列治疗原则在临床获得更好地应用.     

合作动机与信任:基于不确定性简化机制的研究

信任是对他人合作行为的预期。Luhmann认为信任是简化不确定性的重要机制。合作动机高的个体有着更高的简化不确定性的需求,从而可能产生更高的信任水平。文章研究了不同合作动机下不确定性对信任的不同影响。实验在社会两难范式下采用不确定性(高、低)和合作动机(高、低)为自变量、信任为因变量的混合设计。结果显示:1.合作动机高的个体更倾向于信任对方;2.合作动机较高时,不确定性增高时个体对他人的信任也增高;合作动机较低时,不确定性增高时个体对他人的信任降低。对此的解释是:不确定性的增高造成个体简化不确定性的需求增高;合作动机高的个体会用信任来简化不确定性,而合作动机低的个体会用不信任来简化不确定性;因此在不确定性增高的情况下,前者对他人的信任程度增强,后者对他人的不信任程度增强。     

从归因视角探讨公共物品两难中惩罚系统对合作的影响

社会两难中惩罚系统对合作的影响是当前的一个研究热点。前人研究发现惩罚系统可以促进合作,但也有学者提出惩罚系统对合作动机具有破坏作用,存在不一致结论。且这些研究大多只关注金钱惩罚而忽略了社会惩罚。本文采用2(惩罚类型:金钱,社会)×2(惩罚频率:高,低)×2(阶段:有惩罚,无惩罚)混合设计,利用"惩罚撤除"实验范式,比较了社会高低频惩罚和金钱高低频惩罚对合作、归因以及预期的影响。并探讨了合作、归因、预期之间的相互关系,结果发现:(1)金钱和社会惩罚均可提高被试合作水平;(2)金钱高频惩罚减少了对合作行为的内归因,惩罚撤除后合作行为下降,而低频惩罚没有出现下降效应;(3)社会惩罚增加了对合作的内归因,高低频惩罚在移除之后均保持较高水平,且之前的惩罚频率越高,保持效果越好;(4)合作、预期与内归因正相关,外归因负相关,同时合作与预期正相关。     

闪光滞后效应并非知觉延迟差异所致

闪光滞后效应(flash-lag effect)是指在与运动物体一致的位置上呈现闪光(flash),知觉上闪光落后于运动物体的视错觉。延迟差异理论认为,产生该现象的原因是视觉系统加工闪光的速度比加工运动物体慢。根据该理论,作者预测:如采用知觉加工速度更快(或更慢)的客体替代闪光,应能相应地产生更小(或更大)的闪光滞后效应。为了检验该预测,作者以"客体突现"(onset)和"客体消失"(offset)替代闪光滞后实验中的闪光,结果发现,"突现"的知觉滞后大于"消失",但时序判断任务表明"突现"的知觉延迟比"消失"短。该结果并不支持延迟差异理论。     

Action blindness in response to gradual changes

The goal of this study is to characterize observers’ abilities to detect gradual changes and to explore putative dissociations between conscious experience of change and behavioral adaptation to a changing stimulus. We developed a new experimental paradigm in which, on each trial, participants were shown a dot pattern on the screen. Next, the pattern disappeared and participants had to reproduce it. In some conditions, the target pattern was incrementally rotated over successive trials and participants were either informed or not of this change. We analyzed both awareness of the changes and the dynamics of behavioral adaptation, in a way that makes it possible to assess both variability and accuracy as they change over time. Results indicate a dissociation between change awareness and behavioral adaptation to the changes, and support the notion that unconscious representations of visual stimuli are more precise and detailed than previously suggested. We discuss the implications of these results for theories of change detection.     

Depression, Anxiety and Anger in Subtypes of Irritable Bowel Syndrome Patients

The present study aimed to elucidate the differences in depression, anxiety, anger, and quality of life in a sample of non-psychiatric IBS patients, starting from the hypothesis that IBS subtypes may have different symptomatic expressions of negative emotions with different outcomes on quality of life measures. Forty-two constipation-predominant IBS (C-IBS) subjects and 44 diarrhea-predominant IBS (D-IBS) subjects, after an examination by a gastroenterologist and a total colonoscopy, underwent a clinical interview and psychometric examination for the assessment of depression, anxiety, anger and quality of life. IBS subtypes showed different symptomatic profiles in depression, anxiety and anger, with C-IBS patients more psychologically distressed than D-IBS subjects. Affective and emotional symptoms should be considered as specific and integral to the syndrome, and recognizing the differences between IBS subtypes may have relevant implications for treatment options and clinical outcome.     

Rational Choice Virtues

In this essay, I review some results that suggest that rational choice theory has interesting things to say about the virtues. In particular, I argue that rational choice theory can show, first, the role of certain virtues in a game-theoretic analysis of norms. Secondly, that it is useful in the characterization of these virtues. Finally, I discuss how rational choice theory can be brought to bear upon the justification of these virtues by showing how they contribute to a flourishing life. I do this by discussing one particular example of a norm - the requirement that agents to honor their promises of mutual assistance - and one particular virtue, trustworthiness.     

差异政治:超越自由主义与社群主义正义之争——I.M.杨的政治哲学研究

在当代西方政治伦理论域中,尽管自由主义和社群主义正义论辩激烈且影响广泛,但在差异政治的主将艾里斯·杨看来,仍不足以应对现代社会多样性的支配与压迫的非正义境况,无论是自由主义的中立性理想还是社群主义的共同体理想都不同程度地培育了对差异的否认,并进而造成了对某些群体和个体的非正义,因而,为削弱"自我发展和自我决定的制度化限制",杨以结构性社群和间接关系为根基尝试性发展了一种差异政治的正义构想.在明同别异的前提下开展差异政治、自由主义与社群主义的多边互动,既为彼此取益,更为深化对马克思主义哲学的当代理解.     

The Role of Occupational Characteristics and Occupational Imbalance in Explaining Well-being

One of the key factors for promoting well-being lies in balancing one’s daily life occupations and the nature of these occupations. Occupation refers to a group of everyday life goal-directed activities which may be associated to any life domain, not necessarily work, such as leisure, education, or self-care. Yet it is not clear what constitutes occupational imbalance, and its association to other factors has not been examined systematically. This study proposed and tested a theoretical model for specifying the structural relationships between occupational imbalance, occupational characteristics, personality and well-being. 288 working adults completed the following questionnaires: Inter-goal Relations Questionnaire (occupational imbalance), Personal Projects Analysis (occupational characteristics), the Big Five Inventory (personality traits) and the Satisfaction with Life Scale (well-being). Twenty-five models were tested using structural equation modeling. All the models fit the data well. Occupational characteristics, with the exception of stress, served as significant mediators between personality and well-being, yet occupational imbalance did not play a significant role across all models. Our findings provide substantial support for the importance of occupation to well-being, however occupational imbalance is still an elusive concept that requires further investigation theoretically and empirically.