Stop that! Inhibition,sensitization, and their neurovisceral concomitants

There is increasing evidence that the behavior of living systems can be conceptualized as a self-organizing dynamical system. Moreover, evidence suggests that inhibitory processes give these systems the flexibility that is necessary for efficient functioning in the face of changing environmental demands. The process of sensitization can be conceived as a breakdown of inhibitory neural processes that can lead to maladaptive, perseverative behavior. In this paper we describe a model of inhibition and sensitization from a dynamical systems perspective. We show that inhibition is important for adaptive behavior across a number of levels of system functioning. Using our work on attention, emotion, and anxiety disorders we show the importance of both central - for example gamma-aminobutyric acid (GABA)-ergic - and peripheral - for example heart rate variability (HRV) - inhibitory processes and how they may be linked by a network of neural structures that guide the organism from one state of relative stability to another.     

Two routes to remembering (and another to remembering not)

In this article, the author presents evidence about 2 mechanisms of remembering that occur when target stimuli are presented in meaningful contexts. One occurs when the context has been seen previously; the other occurs when the context is new in the test. Both appear to result from the construction of expectations and evaluation of outcomes, but the former appears to depend on the formation of definite expectations, whereas the latter appears to depend on indefinite expectations. These 2 routes to remembering are affected by different factors and cause dissociated patterns of remembering. They also have differential significance for claims of clear recall versus a feeling of familiarity. The results are discussed in terms of the SCAPE framework of memory.     

Outcomes of hemisphericity questionnaires correlate with unilateral dichotic deafness

Using the Dichotic Deafness Test, 145 university workers were separated into dichotic deafness and hearing groups based on minor ear responses to dichotic consonant-vowel stimuli. They were also separated into putative right and left brain-oriented groups by Zenhausern's Preference Questionnaire. Interestingly, members of the dichotically hearing group chose mainly right brain-oriented answers and vice versa. A correlation coefficient twice that obtained for Zenhausern's Preference Questionnaire resulted when subject groups separated by the novel Polarity Questionnaire were compared to Dichotic Deafness Test groups. Only 30% of Preference Questionnaire items, versus 90% of Polarity Questionnaire items, were significantly correlated with Dichotic Deafness Test groups. This is the first report of hemisphericity-type questionnaires showing significant correlations with a biophysical measure of brain laterality.     

On Learned Helplessness

"Learned helplessness" and its Pavlovian analog, learned irrelevance, are phenomena thought integral to understanding depression, PTSD, psychosomatic vulnerability, and a variety of diseases and immune disorders. The origin and development of research on learned helplessness is briefly overviewed with attention to the reasons for the controversy that surrounds the study of learned helplessness and derived physiological, psychological, and behavioral phenomena. The need to remedy past focus on American research and English language journals in this area is noted. The heuristic value as well as the wide ranging empirical value of the research domain is lauded. The meretricious emerging social and legal barriers to this research are noted to be unrealistic and unfortunate.     

Magnitude estimation of conceptual data dimensions for use in sonification

Sonifications must match listener expectancies about representing data with sound. Three experiments showed the utility of magnitude estimation for this. In Experiment 1, 67 undergraduates judged the sizes of visual stimuli and the temperature, pressure, velocity, size, or dollars they represented. Similarly, in Experiment 2, 132 listeners judged the pitch or tempo of sounds and the data they represented. In both experiments, polarity and scaling preference depended on the conceptual data dimension. In Experiment 3, 60 listeners matched auditory graphs to data created with the results of Experiment 2, providing initial validation of scaling slopes. Magnitude estimation is proposed as a design tool in the development of data sonifications, with the level of polarity preference agreement predicting mapping effectiveness.     

Primary care physicians attitude toward diagnosis and treatment of late-life depression

Underdiagnosis and undertreatment of late-life depression is common, especially in primary care settings. To help assess whether physicians attitude and confidence in diagnosing and managing depression serve as barriers to care, a total of 176 physicians employed in 18 primary care groups were administered surveys to assess attitudes towards diagnosis, treatment, and management of depression in elderly patients, (individuals over 65 years of age). Logistic regression was performed to assess the association of physician characteristics on attitudes. Nearly all of the physicians surveyed felt that depression in the elderly was a primary care problem, and 41% reported late-life depression as the most common problem seen in older patients. Physicians were confident in their ability to diagnose and manage depression, yet 45% had no medical education on depression in the previous three years. Physicians confidence in their ability to diagnose, treat, and manage depression, and their reported adequacy of training, do not appear to correspond to the amount of continuing medical education in depression, suggesting that physician overconfidence may potentially be serving as a barrier to care.     

Goal specificity and learning with a hypermedia program

Problem solving research has found that a nonspecific goal (NSG) leads to better learning than a specific goal (SG). This effect can be understood in terms of dual-space search theories of problem solving. To apply the theory, we studied goal specificity effects with a hypermedia program in which participants had to learn about the outbreak of World War 1, either with the goal to find twenty dates (i.e., SG) or with the goal to explain the reasons for the war (i.e., NSG). As expected, compared to the SG-group, the NSG-group correctly answered more factual questions about the text during the task, spent more time on average per page, and more often looked for extra information. In a final questionnaire with factual and inferential questions, the NSG-group still performed better than the SG-group. The NSG-group may also show better transfer of what they had learnt to a new situation.     

Relations of Tripartite Dimensions of Emotion to Childhood Anxiety and Mood Disorders

This study examined preliminary higher-order models relating tripartite dimensions of emotion to severity of anxiety and depressive disorders in 100 clinically referred children and adolescents. In light of the accumulating support for multifactor models of vulnerability and negative emotion in children, the present investigation was designed to establish preliminary estimates of the structure and magnitude of the relations of three emotion factors with dimensions of social anxiety, depression, panic, generalized anxiety, obsessions/compulsions, and separation anxiety. Results were consistent with structures that minimally specified two higher-order emotion factors, yet only some parameter estimates were consistent with theory regarding the tripartite model. Problems with the measurement of tripartite factors and possibilities for further research are outlined.     

Metapsychiatry and the Elusive Truth of Being

The legacy of the spiritual teachings of Dr. Thomas Hora (a training analyst at Blanton-Peale), known as Metapsychiatry, is introduced and its approach to and definition of a variety of spiritual terms and ideas is explained. The primacy of the distinction between reality and experience is presented, and the tools for discerning the difference, the two intelligent questions, are described. Brief clarifications of the nature of God, illusion, suffering, love, meditation, and enlightenment are offered, and the meaning of the elusiveness of the truth of being is identified.     

Covert face recognition in neurologically intact participants

Prosopagnosic patients may maintain some ability to recognize familiar faces, although they remain unaware of this ability. This phenomenon – called covert face recognition – was investigated in neurologically intact participants, using priming techniques. Participants were quicker to indicate that a target-name was familiar when the preceding prime-face belonged to the same person compared with an unrelated familiar person. This was observed both when prime-faces could be recognized overtly and when they were presented too briefly to be recognized overtly (Exps. 1 and 2). Thus, covert face recognition was observed in neurologically intact participants. In Exp. 3, participants were quicker to recognize a familiar face when that person's face had been seen previously, but only when it had been recognized overtly on the first encounter. These results are interpreted within the framework of an interactive activation model of face recognition. Received: 21 September 1998 / Accepted: 2 March 1999