盐酸戊乙奎醚对心脏瓣膜置换术患者NF-κB表达的影响

为研究盐酸戊乙奎醚对心脏瓣膜置换术患者心肌NF-κB转录活性的影响,选取择期瓣膜置换术患者60例,随机分为对照组(C)、盐酸戊乙奎醚组1(P1)、盐酸戊乙奎醚组2(P2),每组20例.结果心肌缺血再灌注后,P1、P2组NF-κB的转录活性明显下降,可见盐酸戊乙奎醚可以抑制心肌NF-κB的激活,在一定程度上具有心肌保护作用.     

Muscle and fat aftereffects and the role of gender: Implications for body image disturbance

Body image disturbance – a cause of distress amongst the general population and those diagnosed with various disorders – is often attributed to the media’s unrealistic depiction of ideal bodies. These ideals are strongly gendered, leading to pronounced fat concern amongst females, and a male preoccupation with muscularity. Recent research suggests that visual aftereffects may be fundamental to the misperception of body fat and muscle mass – the perceptual component of body image disturbance. This study sought to establish the influence of gender on these body aftereffects. Male and female observers were randomly assigned to one of four adaptation conditions (low-fat, high-fat, low-muscle, and high-muscle bodies) and were asked to adjust the apparent fat and muscle levels of male and female bodies to make them appear as ‘normal’ as possible both before adaptation and after adaptation. While neither the gender of observers nor of body stimuli had a direct effect, aftereffect magnitude was significantly larger when observers viewed own-gender (compared with other-gender) stimuli. This effect, which may be due to attentional factors, could have implications for the development of body image disturbance, given the preponderance of idealized own-gender bodies in media marketed to male and female consumers.     

数学焦虑影响儿童的数量表征:认知抑制的调节作用

为了考察数学焦虑对儿童数量表征表现的可能影响及认知抑制的潜在调节作用,选取70名小学三年级儿童（高焦虑组36人,低焦虑组34人）为被试,在对抑制条件进行操控的情况下,要求其完成符号、非符号数量表征任务。结果发现,被试在两种数量表征任务中均出现距离效应,与符号数量比较任务相比,高焦虑组在非符号数量比较任务中的正确率显著低于低焦虑组,且高焦虑组表现出了更强的距离效应。鉴于非符号数量比较任务更能反映出个体近似数量系统（ANS）的敏锐性,上述结果意味着高数学焦虑儿童的数量表征更不精确,其在相对复杂问题上较差的表现或许源于基本数量能力缺陷。本研究还发现认知抑制能够调节数学焦虑对个体非符号数量表征的影响,抑制条件下高低焦虑组儿童在正确率指标上的差异大于非抑制条件,抑制条件的设置提高了个体对工作记忆资源的需求,此时焦虑情绪对认知资源的消耗会造成任务所需资源的不足,进而削弱高焦虑个体的认知效用。     

The rise and fall of moral algebra: Francis Hutcheson and the mathematization of psychology

Until recently historians of psychology have typically argued that mathematical analysis in psychology originated with Herbart in nineteenth-century Germany. Among those who are now recognized to have pedated Herbart is Francis Hutcheson. In 1725, Hutcheson published a mathematical statement of his theory of the psychological basis of moral behavior and judgment. Hutcheson's attempt to present a theory of social behavior in mathematical terms is described and an analysis is presented of the background which led Hutcheson to adopt such a mathematical format. The work of several imitators of this aspect of Hutcheson's opus is considered and the role of his critic, Thomas Reid, in halting such mathematizing efforts for several decades in Britain is noted.     

Five Years, Twelve Steps, and REBT in the Treatment of Dual Diagnosis

A five-year NIDA-funded grant is described that compared client-centered 12-step-oriented and REBT/SMART Recovery-oriented intensive outpatient treatment/partial hospitalization programs with severely impaired clients with dual diagnosis (serious mental illness/substance abuse). Results are presented and suggestions made for applying the findings.     

The Relationship Among Substance Abuse Counselors' Spiritual Well‐Being,Values, and Self‐Actualizing Characteristics and the Impact on Clients' Spiritual Well‐Being

This study explored the relationship between scores on the Spiritual Well‐Being Scale and subscales from the Rokeach Value Survey and the Personal Orientation Inventory of substance abuse counselors in the Commonwealth of Virginia. This study also examined the impact of counselors' spiritual well‐being on the spiritual well‐being of patients in their clinical care. The results indicated that the values of wisdom and loving from the Rokeach Value Survey and self‐acceptance from the Personal Orientation Inventory accounted for approximately half of the spiritual well‐being variance. These variables could be used as indicators in the supervisory process, could help promote substance abuse counselors' spiritual well‐being, and could educate counselors on burnout prevention. Follow‐up findings indicated a statistically significant change score on patients' pretest and posttest scores on the Spiritual Well‐Being Scale, indicating an increase in patients' spiritual wellbeing while in inpatient addiction treatment.     

Enhancing Parenting Skills Among Nonresident African American Fathers as a Strategy for Preventing Youth Risky Behaviors

This study evaluated the effectiveness of a theoretically based, culturally specific family intervention designed to prevent youth risky behaviors by influencing the parenting attitudes and behaviors of nonresident African American fathers and the parent–child interactions, intentions to avoid violence, and aggressive behaviors of their preadolescent sons. A sample of 158 intervention and 129 comparison group families participated. ANCOVA results indicated that the intervention was promising for enhancing parental monitoring, communication about sex, intentions to communicate, race-related socialization practices, and parenting skills satisfaction among fathers. The intervention was also beneficial for sons who reported more monitoring by their fathers, improved communication about sex, and increased intentions to avoid violence. The intervention was not effective in reducing aggressive behaviors among sons. Findings are discussed from a family support perspective, including the need to involve nonresident African American fathers in youth risky behavior prevention efforts.