Why do they exercise less? Barriers to exercise in high-anxiety-sensitive women

Anxiety sensitivity (AS; fear of arousal sensations) is a risk factor for mental and physical health problems, including physical inactivity. Because of the many mental and physical health benefits of exercise, it is important to better understand why high-AS individuals may be less likely to exercise. The present study's aim was to understand the role of barriers to exercise in explaining lower levels of physical exercise in high-AS individuals. Participants were undergraduate women who were selected as high (n = 82) or low (n = 72) AS. High-AS women participated in less physical exercise and perceived themselves as less fit than low-AS women. Mediation analyses revealed that barriers to exercise accounted for the inverse relationships between AS group and physical exercise/fitness levels. Findings suggest that efforts to increase physical exercise in at-risk populations, such as high-AS individuals, should not focus exclusively on benefits to exercise but should also target reasons why these individuals are exercising less.     

Relations with Parents and with Peers,Temperament, and Trajectories of Depressed Mood During Early Adolescence

The present study examined (a) whether groups of children can be empirically identified with distinct longitudinal profiles of depressed mood from late childhood through early adolescence, (b) to what extent these different longitudinal depression profiles are predicted by problematic relations with parents, same-sex peers, and other-sex peers, and (c) what role individuals' temperamental characteristics play in this context. Based on a sample of 414 early adolescents (197 girls), four groups were identified with distinct longitudinal profiles of depressed mood between ages 11 and 14: One group with consistently low levels of depressed mood, another with consistently moderate levels of depressed mood, a third group whose depressed mood increased sharply from late childhood through early adolescence, and a fourth group who already showed clinical-range levels of depressed mood during late childhood and whose depressive feelings increased even slightly more thereafter. Subsequent analyses revealed that rejection by same-sex peers was related to the odds of following an increasing trajectory of depressed mood, but only for girls with a highly reactive temperament. A problematic relationship with parents increased the odds of an elevated trajectory of depressed mood regardless of individual temperament. The theoretical and practical implications of these findings are discussed.     

Metaplastic effect of apamin on LTP and paired-pulse facilitation

In area CA1 of hippocampal slices, a single 1-sec train of 100-Hz stimulation generally triggers a short-lasting long-term potentiation (S-LTP) of 1–2 h. Here, we found that when such a train was applied 45 min after application of the small conductance Ca²⁺-activated K⁺ (SK) channel blocker apamin, it induced a long-lasting LTP (L-LTP) of several hours, instead of an S-LTP. Apamin-induced SK channel blockage is known to resist washing. Nevertheless, the aforementioned effect is not a mere delayed effect; it is metaplastic. Indeed, when a single train was delivered to the Schaffer’s collaterals during apamin application, it induced an S-LTP, like in the control situation. At the moment of this LTP induction (15th min of apamin application), the SK channel blockage was nevertheless complete. Indeed, at that time, under the influence of apamin, the amplitude of the series of field excitatory postsynaptic potentials (fEPSPs) triggered by a stimulation train was increased. We found that the metaplastic effect of apamin on LTP was crucially dependent on the NO-synthase pathway, whereas the efficacy of the NMDA receptors was not modified at the time of its occurrence. We also found that apamin produced an increase in paired-pulse facilitation not during, but after, the application of the drug. Finally, we found that the induction of each of these two metaplastic phenomena was mediated by NMDA receptors. A speculative unitary hypothesis to explain these phenomena is proposed.     

Effectiveness of inpatient dialectical behavioral therapy for borderline personality disorder: a controlled trial

Dialectical Behavioral Therapy (DBT) was initially developed and evaluated as an outpatient treatment program for chronically suicidal individuals meeting criteria for borderline personality disorder (BPD). Within the last few years, several adaptations to specific settings have been developed. This study aims to evaluate a three-month DBT inpatient treatment program. Clinical outcomes, including changes on measures of psychopathology and frequency of self-mutilating acts, were assessed for 50 female patients meeting criteria for BPD. Thirty-one patients had participated in a DBT inpatient program, and 19 patients had been placed on a waiting list and received treatment as usual in the community. Post-testing was conducted four months after the initial assessment (i.e. four weeks after discharge for the DBT group). Pre-post-comparison showed significant changes for the DBT group on 10 of 11 psychopathological variables and significant reductions in self-injurious behavior. The waiting list group did not show any significant changes at the four-months point. The DBT group improved significantly more than participants on the waiting list on seven of the nine variables analyzed, including depression, anxiety, interpersonal functioning, social adjustment, global psychopathology and self-mutilation. Analyses based on Jacobson's criteria for clinically relevant change indicated that 42% of those receiving DBT had clinically recovered on a general measure of psychopathology. The data suggest that three months of inpatient DBT treatment is significantly superior to non-specific outpatient treatment. Within a relatively short time frame, improvement was found across a broad range of psychopathological features. Stability of the recovery after one month following discharge, however, was not evaluated and requires further study.     

Social Support,Coping Strategies and Psychological Well-being among Young People Awaiting Employment

Abstract

It is usually thought that unemployed people who experience high levels of social support show greater psychological well-being than those who experience less social support. This relationship is moderated by factors like the coping strategies used to face the disturbance. This article describes a study carried out on a population of young French people awaiting employment following a training course. The results show that the effects of social support on psychological well-being are modulated by the way individuals manage the relationships between the different domains of their life (family, professional, personal, and social).     

What matters in implicit task sequence learning: perceptual stimulus features, task sets, or correlated streams of information?

Implicit task sequence learning may be attributed to learning the order of perceptual stimulus features associated with the task sequence, learning a series of automatic task set activations, or learning an integrated sequence that derives from 2 correlated streams of information. In the present study, our purpose was to distinguish among these 3 possibilities. In 4 separate experiments, we replicated and extended a previous study by Heuer, Schmidtke, and Kleinsorge (2001). The presence or absence of a sequence of tasks, as well as that of a sequence of different task-to-response mappings, was manipulated independently within experiments. Evidence of implicit sequence learning was found only when correlated sequences of tasks and mappings were present. No sequence learning effects were found when only a single task sequence or a single mapping sequence was present, even when the structure of the single sequence was identical to the structure of the integrated sequence of task-mapping combinations. These results suggest that implicit task sequence learning is not dependent on either perceptual learning of stimulus features or automatic task-set activation per se. Rather, it appears to be driven by correlated streams of information.     

Die DPG-Praxis-Studie

All psychotherapeutic methods must be scientifically evaluated. Empirical evaluation of evidence is a prerequisite for acceptance as scientific psychotherapy as well as for payment by health insurance. Currently the psychotherapy methods accepted within the German health system (behavioural therapy, psychodynamic psychotherapy, and analytic psychotherapy) are reviewed by a governmental evaluation committee concerning evidence, necessity and cost-effectiveness. The DPG practice study has basically two aims: 1) to conduct a large naturalistic study to investigate effectiveness, sustainability and economic aspects of psychodynamic and analytic psychotherapy and 2) to offer a framework for psychoanalytic institutes, members, candidates or groups to realize own research ideas by collecting additional data within the study. The present article describes the background, main research questions, structure and design of the DPG practice study with regard to the evaluation questions.     

Cross-modal training induces changes in spatial representations early in the auditory processing pathway

In the ventriloquism aftereffect, brief exposure to a consistent spatial disparity between auditory and visual stimuli leads to a subsequent shift in subjective sound localization toward the positions of the visual stimuli. Such rapid adaptive changes probably play an important role in maintaining the coherence of spatial representations across the various sensory systems. In the research reported here, we used event-related potentials (ERPs) to identify the stage in the auditory processing stream that is modulated by audiovisual discrepancy training. Both before and after exposure to synchronous audiovisual stimuli that had a constant spatial disparity of 15°, participants reported the perceived location of brief auditory stimuli that were presented from central and lateral locations. In conjunction with a sound localization shift in the direction of the visual stimuli (the behavioral ventriloquism aftereffect), auditory ERPs as early as 100 ms poststimulus (N100) were systematically modulated by the disparity training. These results suggest that cross-modal learning was mediated by a relatively early stage in the auditory cortical processing stream.     

Some ethical and legal issues in Germany involving informed consent and patenting

This paper elaborates on discussions in Germany regarding some of the ethical and legal issues in the area of the use and patenting of inventions involving human tissue. The issues discussed pertain to the benefits and problems regarding informed consent and the issue of property rights as they relate to the donation of cells and tissue. An earlier version of this paper was presented at an international conference, “The Ethics of Intellectual Property Rights and Patents,” held in Warsaw, Poland on 23–24 April, 2004.