When emotional valence modulates audiovisual integration

We constantly integrate the information that is available to our various senses. The extent to which the mechanisms of multisensory integration are subject to the influences of attention, emotion, and/or motivation is currently unknown. The ??ventriloquist effect?? is widely assumed to be an automatic crossmodal phenomenon, shifting the perceived location of an auditory stimulus toward a concurrently presented visual stimulus. In the present study, we examined whether audiovisual binding, as indicated by the magnitude of the ventriloquist effect, is influenced by threatening auditory stimuli presented prior to the ventriloquist experiment. Syllables spoken in a fearful voice were presented from one of eight loudspeakers, while syllables spoken in a neutral voice were presented from the other seven locations. Subsequently, participants had to localize pure tones while trying to ignore concurrent visual stimuli (both the auditory and the visual stimuli here were emotionally neutral). A reliable ventriloquist effect was observed. The emotional stimulus manipulation resulted in a reduction of the magnitude of the subsequently measured ventriloquist effect in both hemifields, as compared to a control group exposed to a similar attention-capturing, but nonemotional, manipulation. These results suggest that the emotional system is capable of influencing multisensory binding processes that have heretofore been considered automatic.     

RSK2 signaling in brain habenula contributes to place aversion learning

RSK2 is a Ser/Thr kinase acting in the Ras/MAPK pathway. Rsk2 gene deficiency leads to the Coffin-Lowry Syndrome, notably characterized by cognitive deficits. We found that mrsk2 knockout mice are unable to associate an aversive stimulus with context in a lithium-induced conditioned place aversion task requiring both high-order cognition and emotional processing. Virally mediated shRNA-RSK2 knockdown in the habenula, whose involvement in cognition is receiving increasing attention, also ablated contextual conditioning. RSK2 signaling in the habenula, therefore, is essential for this task. Our study reveals a novel role for RSK2 in cognitive processes and uncovers the critical implication of an intriguing brain structure in place aversion learning.     

Integrative processing of perception and reward in an auditory localization paradigm

Under natural conditions, human beings routinely have to choose among multiple alternatives which are associated with specific outcomes of varying desirability. Typically, decisions are based upon the processing of perceptual input, which introduces additional noise to the system. Bayesian decision theory (BDT) allows us to formalize decision under risk and to predict statistically optimal choice behavior. In the present study, human observers performed a classification task characterized by an extensive amount of perceptual uncertainty (auditory localization). In addition, a spatial reward function was imposed on the task. We set up a BDT model with no free parameters to serve as a benchmark for statistically optimal choices, and tested it against a purely perceptual model and a hybrid, heuristic model. In addition, we tested these three models with free rather than fixed parameters for the perceptual uncertainty and the peak of the reward function. The log likelihoods of the models given the empirical data were determined by means of Monte Carlo simulations. Bayesian model comparison (BMC) revealed that the BDT model with two free parameters was the most plausible among the tested models. The fitted parameter values for the peak of the reward function were consistently smaller than the actual peak reward communicated to the participants. The results are discussed in the context of an internal underweighting of the reward function.     

Train and Retain: National and Regional Policies to Promote the Settlement of Foreign Graduates in Knowledge Economies

Over the last decades, a rapid internationalization of higher education has taken place, while simultaneously many countries have started to promote immigration of the highly skilled to their economies. Increasingly, these two developments have become linked as foreign students are widely seen as the ideal highly skilled immigration candidates to retain. This paper provides a comparative analysis of admission and retention policies towards foreign students in selected industrialized countries, with a specific focus on the regional level, where such policies have only recently evolved. Finally, we ask the question to what extent countries and regions have been successful in retaining foreign graduates for their labor markets and where they have encountered problems.     

An evaluation of in situ training to teach sexual abuse prevention skills to women with mental retardation

The current study evaluated a behavioral skills training (BST) program in combination with in situ training to teach sexual abuse prevention skills to five women with mild to moderate mental retardation. In situ assessments were conducted following BST and in situ training sessions were conducted for those who were unable to demonstrate the skills in the natural setting. The results showed that generalization of the safety skills to the natural setting occurred for three of the five participants following one to two in situ training sessions. One participant required 12 in situ training sessions and three booster training sessions to reach criterion level. Three of four participants assessed 1 month following training maintained the skills. Copyright © 2007 John Wiley & Sons, Ltd.     

Chronic work stress and exhaustion is associated with higher allostastic load in female school teachers

Epidemiological studies have shown that chronic work stress or unfavourable psychosocial work conditions are prospectively associated with different adverse health outcomes. The aim of the present cross-sectional study was to investigate the relationship between work-related chronic stress as well as exhaustion and a cumulative measure of physiological wear-and-tear called allostastic load (AL). AL could be a possible biological pathway for how chronic work stress and exhaustion lead to health impairments in the long run. As the teaching profession has been proposed to be a potentially high stressful occupation, chronic work stress (effort-reward-imbalance) and exhaustion were assessed in 104 female school teachers. AL was first analyzed according to McEwen's classical model comprised of ten parameters including cortisol, epinephrine and norepinephrine, dehydroepiandrosterone-sulphate (DHEA-S), waist/hip-ratio (WHR), glycosylated haemoglobin (HbA1c), high-density lipoprotein (HDL), total cholesterol/HDL-ratio, and systolic and diastolic blood pressure. Additionally it was extended to include tumor-necrosis-factor-alpha (TNF-alpha), C-reactive protein (CRP), fibrinogen, D-dimer, percent-body-fat, triglycerides, and glucose levels. A substantial proportion of our sample was highly exhausted whereas relatively few teachers showed high effort-reward-imbalance. AL scores were significantly higher in women high on effort-reward-imbalance or suffering from exhaustion. Although all teachers had been in a good health status, chronic work stress as well as exhaustion appears to be associated with changes in a multi-system summary indicator of physiological risk.     

Early development of gaze following into distant space in juvenile Greylag geese (Anser anser)

Visual co-orientation with another's gaze direction (gaze following) may provide important information about the location of food, social interactions or predators. Gaze following has been shown in a variety of mammals, but only in few bird species, and has not been tested in precocial birds at all. It has been suggested that gaze following is an anti-predator behaviour, and in Common ravens (Corvus corax) and rooks (C. frugilegus), it emerges shortly after fledging, at a time when young birds leave the predator-safe nest. However, if gaze following is adaptive, the developmental pattern should differ between altricial and precocial birds. Greylag geese (Anser anser) are highly social birds with a precocial development. Goslings move and feed independently within 24 h post-hatching, and they are highly vulnerable to aerial predators. We therefore predicted that greylag geese are capable of gaze following and that they develop this skill already pre-fledging. We experimentally tested 19 hand-raised greylag goslings for their ability to follow a conspecific's gaze when they were between 10 days and 6 weeks old. In line with our predictions, first responses were already detectable in 10-day-old goslings. Our results therefore not only demonstrate that greylag geese follow the gaze of conspecifics into distant space, but that they also develop this ability much earlier than altricial birds.     

Why do they exercise less? Barriers to exercise in high-anxiety-sensitive women

Anxiety sensitivity (AS; fear of arousal sensations) is a risk factor for mental and physical health problems, including physical inactivity. Because of the many mental and physical health benefits of exercise, it is important to better understand why high-AS individuals may be less likely to exercise. The present study's aim was to understand the role of barriers to exercise in explaining lower levels of physical exercise in high-AS individuals. Participants were undergraduate women who were selected as high (n = 82) or low (n = 72) AS. High-AS women participated in less physical exercise and perceived themselves as less fit than low-AS women. Mediation analyses revealed that barriers to exercise accounted for the inverse relationships between AS group and physical exercise/fitness levels. Findings suggest that efforts to increase physical exercise in at-risk populations, such as high-AS individuals, should not focus exclusively on benefits to exercise but should also target reasons why these individuals are exercising less.     

Decoupling neural networks from reality: dissociative experiences in torture victims are reflected in abnormal brain waves in left frontal cortex

From a neuroscience perspective, little is known about the long-term effect of torture. Dissociative experiences and posttraumatic stress disorder are often the results of this experience. We examined psychological dissociation within a group of 23 torture victims and report its manifestations within neural networks in the human brain. In particular, we observed that dissociative experiences are associated with slow abnormal brain waves generated in left ventrolateral frontal cortex. Given that focal slow waves often result from depriving neural networks of major input, the present results may indicate decoupling of frontal affective processors from left cortical language areas. This interpretation is consistent with the fact that disturbed access to structured verbal memory concerning traumatic events is a core feature of the dissociative experience.