发展性面孔失认的认知机制及其神经基础

发展性面孔失认症是指个体在童年期就开始表现出来的一种终生性面孔识别缺陷,其不能归因于智力衰退、情感障碍、物体识别困难以及后天性脑损伤.发展性面孔失认症涉及的认知机制包括面孔特异性机制、构型加工障碍、面孔探测、面孔记忆和面孔身份识别.此外,该面孔失认症的神经网络由核心神经网络和延伸的神经网络组成,前者与面孔选择反应和记忆表征有关,后者主要负责面孔知识表征、面孔长时记忆和面孔工作记忆.今后的研究应集中在完善延伸的神经网络、拓展其认知网络;进一步明确面孔探测与发展性面孔失认之间的关系;考察发展性面孔失认症的基因基础、加强其发展性研究以及推动康复工作的展开.     

Resistance,reactance, and misinterpretation: Highlighting the challenge of persuading people with depression to seek help

Interventions that increase help‐seeking among people with depression have the potential to save lives. Several efforts have been impressively successful; however, research has also chronicled inconsistent results, with some endeavors indicating boomerang effects. The goal of the current analysis is to synthesize select findings from cognitive theorizing on depression with persuasion scholarship to explain how and why the combination of unfavorable attitudes toward help‐seeking, attitudes that are increasingly resistant to influence, psychological reactance, and cognitive errors can result in challenging responses to messages encouraging help‐seeking among people with depression. In addition, we highlight the importance of utilizing theory‐based approaches to circumvent resistance to persuasion and provide an explanation as to why the provision of immediate help‐seeking mechanisms could be a key aspect of successful intervention efforts. We also stress the importance of formative research and pilot testing, and warn against the potentially harmful error of assessing messages targeting people with depression on those without heightened levels of depressive symptomatology. Ideally, this effort will draw attention to the challenge of persuading people with depression to seek help and also motivate social psychologists to consider the ways they can use their craft to positively influence the health and well‐being of people with depression.     

Prediction and uncertainty in associative learning: examining controlled and automatic components of learned attentional biases

It has been suggested that attention is guided by two factors that operate during associative learning: a predictiveness principle, by which attention is allocated to the best predictors of outcomes, and an uncertainty principle, by which attention is allocated to learn about the less known features of the environment. Recent studies have shown that predictiveness-driven attention can operate rapidly and in an automatic way to exploit known relationships. The corresponding characteristics of uncertainty-driven attention, on the other hand, remain unexplored. In two experiments we examined whether both predictiveness and uncertainty modulate attentional processing in an adaptation of the dot probe task. This task provides a measure of automatic orientation to cues during associative learning. The stimulus onset asynchrony of the probe display was manipulated in order to explore temporal characteristics of predictiveness- and uncertainty-driven attentional effects. Results showed that the predictive status of cues determined selective attention, with faster attentional capture to predictive than to non-predictive cues. In contrast, the level of uncertainty slowed down responses to the probe regardless of the predictive status of the cues. Both predictiveness- and uncertainty-driven attentional effects were very rapid (at 250?ms from cue onset) and were automatically activated.     

Seeking positive experiences can produce illusory correlations

Individuals tend to select again alternatives about which they have positive impressions and to avoid alternatives about which they have negative impressions. Here we show how this sequential sampling feature of the information acquisition process leads to the emergence of an illusory correlation between estimates of the attributes of multi-attribute alternatives. The sign of the illusory correlation depends on how the decision maker combines estimates in making her sampling decisions. A positive illusory correlation emerges when evaluations are compensatory or disjunctive and a negative illusory correlation can emerge when evaluations are conjunctive. Our theory provides an alternative explanation for illusory correlations that does not rely on biased information processing nor selective attention to different pieces of information. It provides a new perspective on several well-established empirical phenomena such as the ‘Halo’ effect in personality perception, the relation between proximity and attitudes, and the in-group out-group bias in stereotype formation.     

Developing an outcome-based assessment for family therapy training: the Rochester Objective Structured Clinical Evaluation (ROSCE)

This paper addresses a growing need for cost-effective, outcome-based assessment in family therapy training. We describe the ROSCE, a structured, evidence-informed, learner-centered approach to the assessment of clinical skills developed at the University of Rochester Medical Center. The ROSCE emphasizes direct observation of trainees demonstrating clinical competencies. The format integrates both formative and summative assessment methods. It can readily be adapted to a wide variety of educational and training settings.     

The organization of narrative discourse in Lewy body spectrum disorder

Narrative discourse is an essential component of day-to-day communication, but little is known about narrative in Lewy body spectrum disorder (LBSD), including Parkinson’s disease (PD), Parkinson’s disease with dementia (PDD), and dementia with Lewy bodies (DLB). We performed a detailed analysis of a semi-structured speech sample in 32 non-aphasic patients with LBSD, and we related their narrative impairments to gray matter (GM) atrophy using voxel-based morphometry. We found that patients with PDD and DLB have significant difficulty organizing their narrative speech. This was correlated with deficits on measures of executive functioning and speech fluency. Regression analyses associated this deficit with reduced cortical volume in inferior frontal and anterior cingulate regions. These findings are consistent with a model of narrative discourse that includes executive as well as language components and with an impairment of the organizational component of narrative discourse in patients with PDD and DLB.     

Personality differences between alcohol abusers and matched controls: Relation to frontal symptoms and subtypes of addicts

Epidemiological studies usually show a link between personality disorders and addictions. Dimensional models of personality, such as that of Cloninger, are able to diagnose and discriminate between transient dysfunctional behavior styles and relatively more stable traits. Certain brain areas have been proposed, as trait locations, based on their activation. This paper explores differences in personality traits among a sample of alcohol abusers (N= 95) and a control group of non-clinical population (N= 95), matched in sociodemographic variables, using the TCI-R-67 and the FrSBe-Sp. It is hypothesized that such differences are associated with frontal symptomatology. The existence of different subgroups of addicts based on certain combinations of traits is also analyzed. Results showed significant differences in two temperament traits (Novelty Seeking and Harm Avoidance) and a characterial trait (Self-Direction). We also found a correlation with a large effect size between these traits and frontal symptomatology. Cluster analysis classified the participants into several subtypes with different combinations of traits that matched diverse frontal symptomatology. Possible neurobiological explanations of these differences and their importance in the clinical practice are discussed.     

New Sexism in Couple Therapy: A Discursive Analysis

The persistence of gender inequality in postindustrial societies is puzzling in light of a plethora of changes that destabilize it, including shifts in economy, legislation, and the proliferation of feminist politics. In family relations, such persistence manifests as a disconnect between couples aspiring to be more egalitarian yet continuing to enact traditional gender roles and hierarchies. There is an emerging consensus that gender inequality persists because of people's continued reliance on sexist ideology or gendered assumptions that constitute women as innately distinct from and inferior to men. Sexist ideology changes its form to accommodate to changing socio‐economic conditions. Contemporary forms of sexism are old ways of legitimizing male power articulated in new and creative ways, often by incorporating feminist arguments. To effectively recognize and address “new sexism,” scholars and practitioners require new, innovative research frameworks. Our objective in writing this article is two‐fold. First, we seek to advance discursive (i.e., focused on language in use) approaches to the study of sexism. Second, we present the results of a discursive analysis of “new” sexist discourse in the context of couple therapy. The study provides preliminary evidence that, despite endorsing egalitarian norms, couples studied continue to rely on gender binaries and remain entrenched in old‐fashioned patterns of gender inequality. Implications of these results for the practice of couple therapy and for future research are discussed.     

常染色体显性多囊肾手术治疗的临床决策

多囊肾去顶减压术是目前治疗常染色体显性多囊肾的主要手术方式。为了探讨多囊肾去顶减压术的临床效果,本文对81例常染色体显性多囊肾患者进行研究,分析其术后肾功能和症状改善情况。本文旨在客观评价多囊肾去顶减压术,并指出选择适当的手术时机是获得满意疗效的关键,为临床决策提供了依据。