Associations between serum cortisol, cardiovascular function and neurological outcome following acute global hypoxia in the newborn piglet

Perinatal asphyxia is a significant contributor to neonatal brain injury. However, there is significant variability in neurological outcome in neonates after global hypoxia-ischemia. The aims of this study were to identify which physiological response/s during global hypoxia-ischemia influence the severity of brain injury and to assess their relative importance. Hypoxia/hypercapnia was induced in 20 anaesthetized piglets by reducing the inspired oxygen fraction to 10% and the ventilation rate from 30 to 10 breaths per minute for 45 min. Neurological outcome was assessed using functional markers including cerebral function amplitude (via electroencephalography) and cerebral impedance, and the structural marker microtubule associated protein-2 by immunohistochemistry at 6 h post hypoxia. Significant variability in neurological outcome was observed following the constant hypoxia/hypercapnia insult. There was a high degree of variability in cardiovascular function (mean arterial blood pressure and heart rate) and serum cortisol concentrations in response to hypoxia. More effective maintenance of cardiovascular function and higher serum cortisol concentrations were associated with a better outcome. These two variables were strongly associated with neurological outcome, and together explained 68% of the variation in the severity of neurological outcome. The variability in the cardiovascular and cortisol responses to hypoxia may be a more important determinant of neurological outcome then previously recognized.     

Risk factors in child maltreatment: A meta-analytic review of the literature

This review presents the results of a series of meta-analyses identifying the relative strength of various risk factors for child physical abuse and neglect. Data from 155 studies examining 39 different risk factors were included in the review. Large effect sizes were found between child physical abuse and three risk factors (parent anger/hyper-reactivity, family conflict and family cohesion). Large effect sizes were also found between child neglect and five risk factors (parent–child relationship, parent perceives child as problem, parent's level of stress, parent anger/hyper-reactivity, and parent self-esteem).     

Preschoolers continue to trust a more accurate informant 1 week after exposure to accuracy information

To determine whether children retain a preference for a previously accurate informant only in the short term or for long‐term use, 3‐ and 4‐year‐old children were tested in two experiments. In both experiments, children were given accuracy information about two informants and were subsequently tested for their selective trust in the two informants (Experiment 1: immediately, 1 day and 1 week later; Experiment 2: immediately, 4 days and 1 week later). Both age groups preferred to trust the accurate informant not only immediately after receiving accuracy information but also at subsequent time‐points. Children who were immediately able to explicitly identify the accurate informant were significantly more likely to seek and accept information from her 1 week later. However, even when they had not been asked to explicitly identify the accurate informant both age groups still maintained their preference for her. Thus, by 3 years of age, children spontaneously choose a previously accurate informant up to 1 week after exposure to information regarding her accuracy.     

Religion and cognitive processing of trauma among newly returned US Iraq and Afghanistan veterans

Religion can provide a powerful meaning-making framework that promotes adaptive processing of potentially traumatic events. However, spiritual strain or distress might be associated with maladaptive perceptions of the meaning of possible traumas. These theoretical propositions have yet to be tested in the empirical literature (to our knowledge). This study examined associations between adaptive and maladaptive religious factors – labelled “seeking religious support” and “spiritual distress” and cognitive processing of trauma in a sample of 90 Iraq and Afghanistan Veterans recently returned from deployments. Results indicated that seeking religious support was positively, and spiritual distress was negatively, associated with adaptive processing but neither were linked with maladaptive meanings of trauma in the presence of known covariates (posttraumatic stress, depression, combat exposure, and social support). These findings demonstrate that religious/spiritual beliefs and behaviours may affect how trauma is adaptively processed in the months following war-zone deployments.     

The oedipal wound in two stories by Kafka: The Metamorphosis and A Country Doctor

Kafka read Freud and was interested in psychoanalysis but believed there was no ‘cure’ for what was essentially the problem of living. As always with creative artists, the writer is his own psychoanalyst, and the actual process of writing is his means of self-revelation. The aim of this paper is to consider, in relation to two stories (The Metamorphosis and A Country Doctor), Kafka’s use of this background oedipal conflict with his father or received values (the ‘law’) as a springboard for the type of wound that results in creative writing. The wound for him became a kind of personal myth, and was also associated with other painful stimuli, including his tuberculosis and his troubled love affairs, but above all with his identity as a writer. The writing process and the ‘faith-value’ it demands is an underlying metaphor behind these narratives of Kafka’s ‘dream-like inner life’. There are parallels here with Bion’s psychoanalytic philosophy of ‘suffering’ and ‘psyche-lodgement’.     

Personality Assessment Inventory Scores as Predictors of Evaluation Referrals,Evaluator Opinions,and Commitment Decisions in Sexually Violent Predator Cases

We used data from more than 1,500 offenders to examine the association between Personality Assessment Inventory (PAI; Morey, 1991 Morey, L. C. (1991). Personality Assessment Inventory: Professional manual. Odessa, FL: Psychological Assessment Resources. [Google Scholar]) scores and progress through the sexually violent predator (SVP) screening, evaluation, and commitment process. There was no clear association between PAI scores and referrals for full evaluations, but PAI scores were small to moderate predictors of evaluator opinions and diagnoses among offenders who underwent full evaluations. Higher Antisocial Features (ANT) scores were associated with diagnoses of antisocial personality disorder, but this association was moderated by offender response style. ANT scores were more strongly associated with antisocial personality disorder diagnoses among those responding defensively (d = .71) than among those responding openly (d = .48). The mean ANT score among defensive responders diagnosed with antisocial personality disorder was about 55T, suggesting that even moderate ANT scale elevations could indicate a clinically significant level of antisocial traits among some offenders.     

Acquiring Foreign Language Vocabulary Through Meaningful Linguistic Context: Where is the Limit to Vocabulary Learning?

The present studies examined the effects of varying degrees of unfamiliar vocabulary within written discourse on individuals’ abilities to use linguistic context for the purposes of translation and comprehension (i.e., lexical inferencing). Prose varied in the number of foreign words introduced into each sentence (e.g., 0 through 7 content words per sentence). Furthermore, Krashen’s Input Hypothesis and the Evaluation component of the Involvement Load Hypothesis were tested to determine the degree at which non-comprehensible input hinders the ability of a learner to successfully use linguistic context for translation and comprehension. Results indicated that, as the number of foreign words per sentence, i.e., non-comprehensible input, increased the ability to successfully translate foreign words and create situational models for comprehension begins to decrease especially beyond five unfamiliar words per sentence. This result suggests that there is an optimal level of effectiveness in the use of a linguistic context strategy for learning foreign language vocabulary, but also that there is a limit to the strategy’s effectiveness. Implications and applications to the field of foreign language learning are discussed.