Genetic Counseling in the Era of Genomics: What’s all the Fuss about?

As genomic sequencing becomes more widely available in clinical settings for diagnostic purposes, a number of genetic counseling issues are gaining precedence. The ability to manage these issues will be paramount as genetic and non-genetic healthcare professionals navigate the complexities of using genomic technologies to facilitate diagnosis and inform patient management. Counseling issues arising when counseling for diagnostic genomic sequencing were identified by four genetic counselors with 10 years of collective experience providing genetic counseling in this setting. These issues were discussed and refined at a meeting of genetic counselors working in clinical genomics settings in Melbourne, Australia. Emerging counseling issues, or variations of established counseling issues, were identified from the issues raised. Illustrative cases were selected where pre- and post-test genetic counseling was provided in clinical settings to individuals who received singleton or trio WES with targeted analysis. Counseling issues discussed in this paper include a reappraisal of how genetic counselors manage hope in the genomic era, informed consent for secondary use of genomic data, clinical reanalysis of genomic data, unexpected or unsolicited secondary findings, and trio sequencing. The authors seek to contribute to the evolving understanding of genetic counseling for diagnostic genomic sequencing through considering the applicability of existing genetic counseling competencies to managing emerging counseling issues and discussing genetic counseling practice implications.     

Perceived brand authenticity: Examining the effects of inferred dedication and anticipated quality on consumers' purchase intentions and actual choices

This research investigates both the downstream effect of perceived brand authenticity on consumers' actual, consequential choice and the important role of inferred brand dedication in the relationship between perceived brand authenticity, anticipated quality, and purchase intentions. We also investigate the interactive effect of two source-related factors—intrinsic motivation and congruity—on consumers' brand authenticity perceptions. We present findings from three studies using different product categories (utilitarian/consumable: hand sanitizer; hedonic/consumable: chocolate; hedonic/non-consumable: sunglasses). Study 1 shows that consumers use information regarding the intrinsic motivation of those behind the brand and congruity between the brand's actions and what it represents to consumers when forming brand authenticity perceptions and that intrinsic motivation and congruity interact to increase authenticity perceptions. We anticipate that consumers' positivity toward brands perceived as authentic will extend to actual choice through anticipated quality. Study 2 demonstrates that consumers choose authentic brands over inauthentic brands above what chance would dictate and anticipated quality can forecast this choice. Next, we extend our collective process knowledge by exploring an underlying reason why consumers anticipate that brands presented through marketing communications as authentic will have higher quality. We suggest that when managers present brands as authentic, consumers infer greater dedication of those behind the brand and inferred dedication influences anticipated product quality. Study 3 provides support and uncovers a serial mediation process, highlighting the importance of inferred dedication. Specifically, perceived brand authenticity increases consumers' brand dedication inferences, which in turn increases anticipated product quality, and ultimately purchase intentions.     

Motivating Political Participation Among Youth: An Analysis of Factors Related to Adolescents’ Political Engagement

Prior research has identified political efficacy and political interest as strong predictors of political participation, but few studies have examined these two attitudes in tandem or compared their relative importance vis‐à‐vis political participation. Drawing on the expectancy‐value model of motivation, we begin to address this research gap while also considering several related issues. Our sample includes a diverse group of high school students in grades 10, 11, and 12 (N = 422) from the midwestern United States. Through quantitative analyses of participants’ survey data, we found that political interest (a central aspect of value) and political efficacy (closely related to expectancy) predicted participants’ expected future political participation, controlling for background characteristics—and that political interest was a particularly strong predictor. In addition, we identified political‐engagement differences on various demographic measures, such as grade level. We also found a significant interaction between political interest and internal political efficacy, suggesting that high levels of both attitudes can have an especially positive effect on adolescents’ political participation. We discuss the implications of these findings for researchers and educators interested in fostering political engagement among youth.     

Validation Study of the Orientation Model: A Dual‐Process Assessment Framework

The orientation model is a multidimensional dual‐process assessment framework composed of 4 empirically validated instruments of cognitive processing, attachment, empathy, and introspection. It lends counselors a flexible means to assess client processing patterns relevant to clinical practice. The author used 375 participant responses to determine whether selected subscales align with analytic and experiential dual processes. Results suggest that the orientation model can serve as a dispositional framework for counseling practice. Implications and directions for future research are suggested.     

Paying the meter: Effect of metrical similarity on word lengthening

Psychonomic Bulletin & Review - Language has a rhythmic structure, but little is known about the mechanisms that underlie how it is planned. Traditional models of language production assume...     

Human classifier: Observers can deduce task solely from eye movements

Computer classifiers have been successful at classifying various tasks using eye movement statistics. However, the question of human classification of task from eye movements has rarely been studied. Across two experiments, we examined whether humans could classify task based solely on the eye movements of other individuals. In Experiment 1, human classifiers were shown one of three sets of eye movements: Fixations, which were displayed as blue circles, with larger circles meaning longer fixation durations; Scanpaths, which were displayed as yellow arrows; and Videos, in which a neon green dot moved around the screen. There was an additional Scene manipulation in which eye movement properties were displayed either on the original scene where the task (Search, Memory, or Rating) was performed or on a black background in which no scene information was available. Experiment 2 used similar methods but only displayed Fixations and Videos with the same Scene manipulation. The results of both experiments showed successful classification of Search. Interestingly, Search was best classified in the absence of the original scene, particularly in the Fixation condition. Memory also was classified above chance with the strongest classification occurring with Videos in the presence of the scene. Additional analyses on the pattern of correct responses in these two conditions demonstrated which eye movement properties successful classifiers were using. These findings demonstrate conditions under which humans can extract information from eye movement characteristics in addition to providing insight into the relative success/failure of previous computer classifiers.     

Interfaith Groups as Mediating Structures for Political Action: A Multilevel Analysis

This study investigates interfaith groups from across the United States to understand how these religious settings may serve as mediating structures to facilitate individual political action. Based on a multilevel modeling analysis with 169 individuals from 25 interfaith groups, we found that core activities of the group, such as group members sharing community information (e.g., announcing upcoming events, political meetings, community issues) or sharing religious information (e.g., educating members about their religion) positively and negatively predicted individual political action as a result of group participation, respectively. Moreover, a sense that the interfaith group served as a community to work for local change, but not trust within the group, predicted political action as a result of group participation. However, this effect for a sense the group served as a community to work for local change was stronger and more positive as the degree of community information sharing in the group increased. These results show that a core activity of sharing community information may enhance the ability of a group to mediate political action. Overall, these findings demonstrate the potential role of interfaith groups to mediate political action, and show the importance of considering both individual and group characteristics when understanding these religious settings. Limitations and directions for future research are also discussed.     

Recent advances in operant conditioning technology: a versatile and affordable computerized touchscreen system.

We report the construction of a new operant chamber that incorporates modern computer, touchscreen, and display technologies. An LCD display was housed in the front wall of a lightweight Plexiglas chamber. An Apple eMac computer was used to present visual stimuli on the monitor and to control other chamber events. Responses to the stimuli were recorded using a transparent resistive-type touchscreen that overlaid the monitor. The resulting system is simple and inexpensive to construct but powerful and flexible enough to explore a broad range of issues in animal learning and behavior.     

Where to look first for an explanation of induction with uncertain categories

Recent research has examined how people predict unobserved features of an object when its category membership is ambiguous. The debate has focused on whether predictions are based solely on information from the most likely category, or whether information from other possible categories is also used. In the present experiment, we compared these category-based approaches with feature conjunction reasoning, where predictions are based on a comparison among exemplars (rather than categories) that share features with a target object. Reasoning strategies were assessed by examining patterns of feature prediction and by using an eye gaze measure of attention during induction. The main findings were (1) the majority of participants used feature conjunction rather than categorical strategies, (2) people predominantly gazed at the exemplars that were most similar to the target object, and (3) although people gazed most at the most probable category to which an object could belong, they also attended to other plausible category alternatives during induction. These findings question the extent to which category-based reasoning is used for induction when category membership is uncertain.