Role of conditioned reinforcers in the initiation,maintenance and extinction of drug-seeking behavior

The development of a secondary reinforcer as a result of associating a neutral stimulus (buzzer) with intravenous (IV) doses of morphine was studied in rats. Secondary reinforcement developed in the absence of physical dependence and followed the association of the stimulus with either response-contingent or non-contingent injections of morphine. Strength of the conditioned reinforcer, measured in terms of responding on a lever for the stimulus plus infusion of saline solution, was proportional to the unit dosage of morphine employed in pairings of buzzer and drug. When extinction of the lever-press response for IV morphine was conducted (by substituting saline for morphine solution) in the absence of the conditioned reinforcing stimulus, it was seen later that the stimulus could still elicit lever responses, until it too had been present for a sufficient interval of non-reinforced responding. Similarly, extinction of the response for morphine by blocking its action with naloxone in the absence of the stimulus did not eliminate the conditioned reinforcement. Another study showed that a passive, subcutaneous (SC) dose of morphine served to maintain lever-pressing on a contingency of buzzer plus sahne infusion. Furthermore, the stimuli resulting from the presence of morphine (after a SC injection) were able to reinstate the lever-responding with only the buzzer-saline contingency when such responses had previously been extinguished. Moreover, it was shown thatd-amphetamine could restore responding under the same conditions, and that morphine could also do so for rats in which the primary reinforcer had beend-amphetamine. It is suggested that animal data such as these show that procedures designed for the elimination of human drug-taking behavior must take into account secondary reinforcers as well as the primary reinforcer(s).     

Overhabituation and dishabituation: Effects of extraversion and amount of training

The Eysenck (1967) hypothesis that introverts have higher levels of cortical activation than extraverts has received support in a number of psychophysiological studies, though there is not complete consistency. The present study extended the habituation paradigm used in some previous work to include an examination of differences between extraverts and introverts during and following long-term overhabituation. Electrodermal activity was recorded while 72 extraverts and 72 introverts were subjected to criterion auditory habituation to a 1000-Hz, 90-db tone, followed by 60, 100, or 140 trials of overhabituation. The overhabituation run was followed by a test stimulus of 7000 Hz and a final repetition of the standard stimulus. Results showed that introverts increased in response frequency with increasing overhabituation exposure, while extraverts showed an increase only from 100 to 140 trials. In addition, the hypothesis that differences in test response amplitude favoring introverts would be eliminated by extended overhabituation training was supported. Specifically, extraverts showed increased responses at 100 and 140 trials, while introverts remained approximately constant across the three conditions. Finally, results supported the Sokolov hypothesis that overhabituation training produces test responses of larger amplitude.     

Lie to me no more: believable stories and marital affairs.

This case study illustrates the dilemmas of systemic practice when the presenting problem is relational infidelity (marital affairs). After several months of treatment with a structural therapist, the couple and therapist were at an impasse because of arguments over the husband's alleged sexual encounter 3 years previously. The introduction of a consultant and a story-based therapy allowed the couple to reconcile their marital difficulties. The article ends with a discussion of the implications of systemic paradigms and personal morality.