Does frontal brain activity mediate the effect of depression prevention in adolescents? A pilot study

We investigated whether (a) depression prevention was associated with depressive symptoms and medial-frontal alpha asymmetry in adolescents; (b) alpha asymmetry mediated the association between participation in a prevention program and depressive symptoms; and (c) gender affects these associations. In our randomised control group study, we compared a universal prevention program (n = 40 adolescents, 14 females) with a non-intervention control condition (n = 39 adolescents, 20 females) in German secondary school students (mean age: 13.53 years, SD = 0.53). We collected data at baseline, post-intervention, 6-month, and 12-month follow-up using the Self-Rating Questionnaire for Depressive Disorders (SBB-DES) and resting medial-frontal alpha activity on F3 and F4. We found that girls benefitted from participating in the prevention program in regards to their depressive symptoms at 12-month follow-up but not alpha asymmetry. In boys, participation in the prevention program was associated with their alpha asymmetry at 6-month follow-up but not their depressive symptoms. Alpha asymmetry did not mediate the effects of the prevention program on depressive symptoms in either gender. Although participation in the prevention program was associated with both depressive symptoms and alpha asymmetry, those associations seem independent from each other. Possible explanations for this result pattern are discussed.     

Betterness of permissibility

Philosophical Studies - It is often assumed that morally permissible acts are morally better than impermissible acts. We call this claim Betterness of Permissibility. Yet, we show that some...     

Effects of cognitive behavioural therapy and return-to-work intervention for patients on sick leave due to stress-related disorders: Results from a randomized trial

The aim of this study was to evaluate specific effects for patients with adjustment or exhaustion disorder, the Stress subgroup (n = 152), regarding symptom severity and sick leave after CBT, a return-to-work intervention (RTW-I), and a combination of them (COMBO), using data from a randomized trial. In the original study, primary care patients on sick leave (N = 211) were randomized to CBT (n = 64), RTW-I (n = 67), or COMBO (n = 80). Blinded Clinician Severity Rating (CSR) of symptoms and sick leave registry data were primary outcomes. Subgroup analyses showed that for the Stress subgroup, CBT led to greater reduction of symptoms than RTW-I posttreatment, but COMBO did not differ from CBT or RTW-I. Regarding sick leave, there was no difference between treatments in the Stress subgroup. An exploratory analysis of the treatment effects in a subgroup of patients with depression, anxiety or insomnia indicates that RTW-I reduced sick leave faster than CBT. We conclude that CBT may be promising as an effective treatment of stress and exhaustion disorder.     

Is backing grounding?

Separatists are grounding theorists who hold that grounding relations and metaphysical explanations are distinct, yet intimately connected in the sense that grounding relations back metaphysical explanations, just as causal relations back causal explanations. But Separatists have not elaborated on the nature of the ‘backing’ relation. In this paper, I argue that backing is a form of (partial) grounding. In particular, backing has many of the properties commonly attributed to grounding, and taking backing to be partial grounding allows Separatists to make the most of their position vis-à-vis their Unionist opponents.     

Illusory trust: Kanizsa shapes incidentally increase trust and willingness to invest

Previous research has shown that the completion of basic perceptual processes is intrinsically pleasant. In the absence of diagnostic and objective cues to trustworthiness, nondiagnostic factors such as positive affect can incidentally lead to reported and behavioral trust. On the basis of these two premises, it was tested whether positive affect from the completion of perceptual processes has implications for the formation of trust in first-time business-consumer interactions. We tested this hypothesis in four experiments, using the famous Kanizsa illusion as an exemplary perceptual process that has been shown to trigger positive affect. We found that participants trusted companies who featured a Kanizsa shape as their logo more than companies with closely matched logos that did not allow for the completion of a basic perceptual process. This was evident on self-reported (Experiment 1) as well as behavioral (Experiments 2–4) measures of trust. This effect even persisted under incentivized conditions (Experiment 4) and was partially mediated by the intrinsic pleasantness of perception (Experiment 3). These findings for the first time demonstrate that positive affect is not the only consequence of perception, but rather has further trickle-down consequences for social judgments and economic decision making. Perceptual illusions seem to elicit illusory trust. Therefore, these novel findings bear important implications not only for both logo design and marketing but also for consumer decision making.     

Task concentration training versus applied relaxation, in combination with cognitive therapy, for social phobia patients with fear of blushing, trembling, and sweating

Social phobia patients with fear of blushing, trembling, sweating and/or freezing as main complaint (N = 65) were randomly assigned to either task concentration training (TCT) or applied relaxation (AR) both followed by cognitive therapy (CT). Measurements took place before and after wait-list, after TCT or AR (within-test), after CT (post-test), at 3-months and at 1-year follow-up. Effects were assessed on fear of showing bodily symptoms (the central outcome variable), social phobia, other psychopathology, social skills, self-consciousness, self-focused attention, and dysfunctional beliefs. No changes occurred during wait-list. Both treatments were highly effective. TCT was superior to AR in reducing fear of bodily symptoms and dysfunctional beliefs at within-test. This difference disappeared after CT, at post-test and at 3-months follow-up. However, at 1-year follow-up the combination TCT-CT was superior to AR-CT in reducing fear of bodily symptoms, and effect sizes for TCT-CT reached 3. Furthermore, at all assessment moments TCT or the combination TCT-CT was superior to AR-CT in reducing self-consciousness and self-focused attention. The superior long-term effect of TCT on fear of showing bodily symptoms is explained by lasting changes in attentional focus.     

Spatial frequency processing in schizophrenia: trait or state marker?

B. F. O'Donnell et al. found impaired discrimination performances at low and medium spatial frequencies in patients with schizophrenia. In this study, the authors replicated this finding in a group of remitted, unmedicated, and highly functioning outpatients with spared IQ and attentional functions. However, the deficit was restricted to low spatial frequencies (0.5 cycles/degree), which suggests that this deficit is a trait marker of schizophrenia.     

Remarks on Penrose’s “New Argument”

It is commonly agreed that the well-known Lucas–Penrose arguments and even Penrose’s ‘new argument’ in [Penrose, R. (1994): Shadows of the Mind, Oxford University Press] are inconclusive. It is, perhaps, less clear exactly why at least the latter is inconclusive. This note continues the discussion in [Lindström, P. (2001): Penrose’s new argument, J. Philos. Logic 30, 241–250; Shapiro, S.(2003): Mechanism, truth, and Penrose’s new argument, J. Philos. Logic 32, 19–42] and elsewhere of this question.     

Linking dynamical perceptual decisions at different levels of description in motion pattern formation: computational simulations

A two-level dynamical model of motion pattern formation is developed in which local motion/ nonmotion perceptual decisions are based on inhibitory competition between area V1 detectors responsive to motion-specifying versus motion-independent stimulus information, and pattern-level perceptual decisions are based on inhibitory competition between area MT motion detectors with orthogonal directional selectivity. The model accounts for the effects of luminance perturbations on the relative size of the pattern-level hysteresis effects reported by Hock and Ploeger (2006) and also accounts for related experimental results reported by Hock, Kelso, and Sch?ner (1993). Single-trial simulations demonstrated the crucial role of local motion/nonmotion bistability and activation-dependent future-shaping interactions in stabilizing perceived global motion patterns. Such interactions maintain currently perceived motion patterns by inhibiting the soon-to-be-stimulated motion detectors that otherwise would be the basis for the perception of an alternative pattern.