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H J Brand 《Perceptual and motor skills》1991,73(1):225-226
A statistically significant correlation of 0.618 was obtained between scores from 62 preschool children on the Revised Developmental Test of Visual-Motor Integration and the Copying Test. Merely 38% of Copying Test variance was associated with changes in Test of Visual-Motor Integration variance, so in practice these tests should not be substituted for one another. 相似文献
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Brand M Labudda K Kalbe E Hilker R Emmans D Fuchs G Kessler J Markowitsch HJ 《Behavioural neurology》2004,15(3-4):77-85
A high percentage of Parkinson's disease (PD) patients show cognitive impairments in addition to the cardinal motor symptoms. These deficits primarily concern executive functions most probably linked to dysfunctions in prefrontal regions due to decreased dopaminergic transmission in fronto-striatal loops. To investigate possible associations between decision-making and executive functions in PD, we examined 20 non-demented PD patients and 20 healthy control subjects with a neuropsychological test battery and the Game of Dice Task. In this computerised decision-making task, the rules for gains and losses and the winning probabilities are obvious and stable. Thus, strategic components besides feedback processing might influence decision-making in this task. We found that PD patients were impaired in the Game of Dice task performance and that the frequency of disadvantageous choices correlated with both executive functions and feedback processing. We suggest that decision-making deficits of PD patients in explicit gambling situations might be associated with dysfunctions in two different fronto-striatal loops: the limbic-orbitofrontal-striatal loop, involved in feedback processing, and the dorsolateral prefrontal-striatal loop, involved in executive functions. 相似文献
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Lesion of the ventral periaqueductal gray reduces conditioned fear but does not change freezing induced by stimulation of the dorsal periaqueductal gray 总被引:3,自引:0,他引:3 下载免费PDF全文
Vianna DM Graeff FG Landeira-Fernandez J Brandão ML 《Learning & memory (Cold Spring Harbor, N.Y.)》2001,8(3):164-169
Previously-reported evidence showed that freezing to a context previously associated with footshock is impaired by lesion of the ventral periaqueductal gray (vPAG). It has also been shown that stepwise increase in the intensity of the electrical stimulation of the dorsal periaqueductal gray (dPAG) produces alertness, then freezing, and finally escape. These aversive responses are mimicked by microinjections of GABA receptor antagonists, such as bicuculline, or blockers of the glutamic acid decarboxylase (GAD), such as semicarbazide, into the dPAG. In this work, we examined whether the expression of these defensive responses could be the result of activation of ventral portion of the periaqueductal gray. Sham- or vPAG electrolytic–lesioned rats were implanted with an electrode in the dPAG for the determination of the thresholds of freezing and escape responses. The vPAG electrolytic lesions were behaviorally verified through a context-conditioned fear paradigm. Results indicated that lesion of the vPAG disrupted conditioned freezing response to contextual cues associated with footshocks but did not change the dPAG electrical stimulation for freezing and escape responses. In a second experiment, lesion of the vPAG also did not change the amount of freezing and escape behavior produced by microinjections of semicarbazide into the dPAG. These findings indicate that freezing and escape defensive responses induced by dPAG stimulation do not depend on the integrity of the vPAG. A discussion on different neural circuitries that might underlie different inhibitory and active defensive behavioral patterns that animals display during threatening situations is presented. 相似文献
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Christine Altstötter-Gleich Friederike X.R. GerstenbergMatthias Brand 《Journal of research in personality》2012,46(5):619-622
The present study explored the influence of dispositional perfectionism (i.e. perfectionistic concerns and perfectionistic strivings) on tension and performance under low or high experimentally induced stress. Results support the moderating role of perfectionism concerning tension and indicate that stress-related processes underlie the vulnerability of perfectionistic concerns. In addition, buffering effects of perfectionistic strivings were found, supporting the 2 × 2 model of dispositional perfectionism by Gaudreau and Thompson (2010). No evidence was found for the moderating role of perfectionistic strivings concerning performance, but results provide evidence for positive effects of perfectionistic concerns on performance. 相似文献
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Published psychological research attempting to support the existence of small and medium effect sizes may not have enough participants to do so accurately, and thus, repeated trials or the use of multiple items may be used in an attempt to obtain significance. Through a series of Monte-Carlo simulations, this article describes the results of multiple trials or items on effect size estimates when the averages and aggregates of a dependent measure are analyzed. The simulations revealed a large increase in observed effect size estimates when the numbers of trials or items in an experiment were increased. Overestimation effects are mitigated by correlations between trials or items, but remain substantial in some cases. Some concepts, such as a P300 wave or a test score, are best defined as a composite of measures. Troubles may arise in more exploratory research where the interrelations among trials or items may not be well described. 相似文献
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Abstract The icosahedral quasicrystals i-AIMn, isomorphically substituted by 28 at.% Fe or by a mixture of (CrFe) atoms, have been studied for the first time by in-field Mössbauer spectroscopy in order to determine the sign and asymmetry parameter of the dominant electric-field gradient (EFG) term. In addition, the orthorhombic o-Al(MnFe) and cubic α- and hexagonal β-Al(MnFe)Si crystalline phases have been studied. We show that the previous Mössbauer results are inadequate for determining whether there are two sites in the quasicrystalline structure in the ratio of the golden number. Our results for i-Al(MnFe) show that the dominant EFG is negative, with an asymmetry parameter of about 0·6. For i-Al(CrFe), essentially no deviations are found from the model of Czjzek or the Gaussian isotropic model. One crystalline phase, the hexagonal β phase, is found to have a very similar quadrupole effect to that found in i-Al(MnFe). In addition it is found that this phase undergoes a change which is at least partly of magnetic origin. 相似文献