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The major objectives of this project were to develop and evaluate a brochure to help parents make an informed decision about participation in a fragile X newborn screening study. We used an iterative development process that drew on principles of Informed Decision Making (IDM), stakeholder input, design expertise, and expert evaluation. A simulation study with 118 women examined response to the brochure. An independent review rated the brochure high on informational content, guidance, and values. Mothers took an average of 6.5 min to read it and scored an average of 91.1 % correct on a knowledge test. Most women rated the brochure as high quality and trustworthy. When asked to make a hypothetical decision about study participation, 61.9 % would agree to screening. Structural equation modeling showed that agreement to screening and decisional confidence were associated with perceived quality and trust in the brochure. Minority and white mothers did not differ in perceptions of quality or trust. We demonstrate the application of IDM in developing a study brochure. The brochure was highly rated by experts and consumers, met high standards for IDM, and achieved stated goals in a simulation study. The IDM provides a model for consent in research disclosing complicated genetic information of uncertain value.  相似文献   
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The objective of this pilot study was to investigate the effects on cognitive performance of progressively adding tasks specific to ice hockey (skating, stick handling, and obstacle avoidance) during a visual interference task (Stroop Color Word Test-interference condition). In addition, the effects on locomotor performance of progressively adding tasks of stickhandling, visual interference, and obstacle avoidance related to maximal skating speed and minimal obstacle clearance were investigated in eight male athletes ages 10 to 12 years. Results revealed decreased performance on both cognitive and physical measures with increased task complexity, suggesting that adding complexity to an environment influences hockey skill performance.  相似文献   
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The author argues that ontological randomness is genuine, and that God does not determine the outcome of every scientifically random event, but instead controls randomness by setting broad boundaries. Through paleontological examination, this paper looks at how randomness shapes the world from the bottom up. However, the phenomena known as convergence indicate that evolution through natural selection may proceed along various paths, but the destinations are few. Thus there is a dichotomy: randomness is constrained within pattern.  相似文献   
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A number of theologians engaged in the theology and science dialogue—particularly Pentecostal theologian Amos Yong—employ emergence as a framework to discuss special divine action as well as causation initiated by other spiritual realities, such as angels and demons. Mikael and Joanna Leidenhag, however, have issued concerns about its application. They argue that Yong employs supernaturalistic themes with implications that render the concept of emergence obsolete. Further, they claim that Yong's use of emergence theory is inconsistent because he highlights the ontological independence of various spirits in the world concurrently with his advocation of supervenience theory. In view of these concerns, Leidenhag and Leidenhag urge Yong to depart from his application of emergence theory. In what follows, we plan to address each of these criticisms and demonstrate that they are tenuous, if not unwarranted, especially in light of a kenotic‐relational pneumatology.  相似文献   
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Dualism holds (roughly) that some mental events are fundamental and non-physical. I develop a prima facie plausible causal argument for dualism. The argument has several significant implications. First, it constitutes a new way of arguing for dualism. Second, it provides dualists with a parity response to causal arguments for physicalism. Third, it transforms the dialectical role of epiphenomenalism. Fourth, it refutes the view that causal considerations prima facie support physicalism but not dualism. After developing the causal argument for dualism and drawing out these implications, I subject the argument to a battery of objections. Some prompt revisions to the argument. Others reveal limitations in scope. It falls out of the discussion that the causal argument for dualism is best used against physicalism as a keystone in a divide and conquer strategy.  相似文献   
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