The ameliorating effect of oroxylin A on scopolamine-induced memory impairment in mice

Oroxylin A is a flavonoid and was originally isolated from the root of Scutellaria baicalensis Georgi., one of the most important medicinal herbs in traditional Chinese medicine. The aim of this study was to investigate the ameliorating effects of oroxylin A on memory impairment using the passive avoidance test, the Y-maze test, and the Morris water maze test in mice. Drug-induced amnesia was induced by administering scopolamine (1 mg/kg, i.p.) or diazepam (1 mg/kg, i.p.). Oroxylin A (5 mg/kg) significantly reversed cognitive impairments in mice by passive avoidance and the Y-maze testing (P<.05). Oroxylin A also improved escape latencies in training trials and increased swimming times and distances within the target zone of the Morris water maze (P<.05). Moreover, the ameliorating effects of oroxylin A were antagonized by both muscimol and diazepam (0.25 mg/kg, i.p., respectively), which are GABA(A) receptor agonists. Furthermore, oroxylin A (100 microM) was found to inhibit GABA-induced inward Cl(-) current in a single cortical neuron. These results suggest that oroxylin A may be useful for the treatment of cognitive impairments induced by cholinergic dysfunction via the GABAergic nervous system.     

情绪对学习不良青少年选择性注意和持续性注意的影响

以学习不良青少年为被试,采用成绩反馈法诱发情绪,考察了情绪对学习不良青少年选择性注意和持续性注意的影响,结果表明：（1）情绪会影响学习不良青少年的选择性注意,具有积极低唤醒情绪的学习不良青少年,他们的选择性注意的反应时显著短于消极情绪下的被试;(2)学习不良青少年的情绪会影响到他们的持续性注意能力,消极高唤醒的情绪能够增加虚报率,而积极高唤醒的情绪能够提高判断标准,降低虚报率     

区块与事件相关混合设计:一种新的fMRI研究范式

本文在对区块设计和事件相关设计进行简要回顾的基础上,介绍了当前fMRI研究中一种新的研究范式——区块与事件相关混合设计。这种研究范式能够有效地分离认知加工过程中持久的、状态相关的过程与短暂的、项目相关的过程,并且已经在fMRI研究中得到了初步的应用。文章最后指出了使用这种研究范式时需要注意的一些问题,并且指出了其在认知科学研究中的应用前景。     

Agreement in personality judgments within and between nonoverlapping social groups in collectivist cultures

The social context hypothesis states that people behave differently in different social groups because group norms and context-specific interpersonal relationships uniquely affect behavior. Consequently, a person who is a member of different, nonoverlapping social groups (i. e., the members of different groups are unacquainted) should be judged consensually on personality traits within each group; however, between groups there should be less agreement in judgments. This research focused on cultural moderation of the social context effect in two collective cultures (China and Mexico) with different norms for interpersonal relationships. Among Chinese, there was greater consensus in trait judgments within groups than between groups, whereas in Mexico, agreement within and between groups was equivalent. Culturally based relationship norms that affect cross-context consistency of behavior and, in turn, the consistency of trait judgments across groups were described.     

Effects of mothers' perceptions of children's competence: the moderating role of mothers' theories of competence

There is much evidence that parents' perceptions of children's competence affect the development of children's academic functioning. In the current research, the possibility that this is moderated by parents' theories about the stability of competence was examined. In a 2-wave, 1-year study of 126 children (9 to 12 years old) and their mothers, children's academic functioning (i.e., grades, perceptions of competence, attributions for performance, and mastery orientation) and affective functioning (i.e., self-esteem and depressive symptoms) were examined. Among mothers with relatively high entity theories, their perceptions acted as self-fulfilling prophecies foreshadowing children's academic and affective functioning over time. However, among mothers with relatively low entity theories, mothers' perceptions did not predict children's academic and affective functioning.     

HIV, Sex, and Social Change: Applying ESID Principles to HIV Prevention Research

The HIV epidemic has been the most significant public health crisis of the last 2 decades. Although Experimental Social Innovation and Dissemination (ESID) principles have been used by many HIV prevention researchers, the clearest application is the series of model-building and replication experiments conducted by Kelly and colleagues. The model mobilized, trained, and engaged key opinion leaders to serve as behavior change and safe-sex endorsers in their social networks. This paper illustrates how ESID principles were used to develop, test, and disseminate an innovative social model and discusses the challenges of applying ESID methodology in the midst of a public health emergency.     

《管子》"道"、"德"的生命特性及对当代生态伦理建设的启示

在存在论的意义上,《管子》中的“道”、“德”是被作为重要的哲学范畴运用的,指生命产生的根源和生命存在的内在根据,二者是一体共在的关系。《管子》的“道”、“德”论揭示了人与万物在自然本性层面上的内在一体性和生态伦理的存在论维度,启示我们生态伦理应超越人与自然的外在关系,建立于人与自然内在关系的基础上。     

Social identity,attribution, and emotion: Comparisons of Americans,Korean Americans,and Koreans

The social identity of another person, in addition to the social identity of self, can be an important factor affecting the types of attribution judgments and emotions that individuals indicate for the other person. In April 2007, the perpetrator of the shooting incident on the Virginia Tech University campus was identified as a person who emigrated to the USA from Korea at a young age. The current study compared non‐Korean Americans, Korean Americans, Koreans in the USA, and Koreans in Korea in terms of their attributions and emotions concerning the perpetrator and the shooting incident. Participants were asked to indicate (1) the extent to which they attributed the cause of the incident to either American society or the perpetrator, (2) their emotions (e.g., upset), and (3) the extent to which they categorized the perpetrator as an American, a Korean American, or a Korean. The results indicated that non‐Korean Americans were most likely to attribute the cause of the incident to the perpetrator as opposed to American society. Non‐Korean Americans, Korean Americans, and Koreans in the United States had more negative emotions (e.g., unhappy, sad, and upset) about the incident than Koreans in Korea did. The results also indicated that individuals differed in their attributions and emotions depending on how they categorized the perpetrator. For example, categorizing the perpetrator as being a Korean was positively related to Americans’ tendency to hold the perpetrator responsible, while categorizing the perpetrator as being an American was negatively related to the tendency to hold the perpetrator responsible among Koreans in Korea. The findings may imply that social identity theory, intergroup emotion theory, and cultural orientations (e.g., individualism and collectivism) can provide insights into people's reactions to a tragic incident.