Avoidance learning facilitates temporal processing in the primary auditory cortex

The primary auditory cortex is now known to be involved in learning and memory, as well as auditory perception. For example, spectral tuning often shifts toward or to the frequency of the conditioned stimulus during associative learning. As previous research has focused on tonal frequency, less is known about how learning might alter temporal parameters of response in the auditory cortex. This study addressed the effects of learning on the fidelity of temporal processing. Adult male rats were trained to avoid shock that was signaled by an 8.0 kHz tone. A novel control group received non-contingent tone and shock with shock probability decreasing over days to match the reduced number of shocks received by the avoidance group as they mastered the task. An untrained (nai ve) group served as a baseline. Following training, neuronal responses to white noise and a broad spectrum of tones were determined across the primary auditory cortex in a terminal experiment with subjects under general anesthesia. Avoidance conditioning significantly improved the precision of spike-timing: the coefficient of variation of 1st spike latency was significantly reduced in avoidance animals compared to controls and nai ves, both for tones and for noise. Additionally, avoidance learning was accompanied by a reduction of the latency of peak response, by 2.0-2.5 ms relative to nai ves and approximately 1.0 ms relative to controls. The shock-matched controls also exhibited significantly shorter peak latency of response than nai ves, demonstrating the importance of this non-avoidance control. Plasticity of temporal processing showed no evidence of frequency specificity and developed independently of the non-temporal parameters magnitude of response, frequency tuning and neural threshold, none of which were facilitated. The facilitation of temporal processing suggests that avoidance learning may increase synaptic strength either within the auditory cortex, in the subcortical auditory system, or both.     

Sex differences in the personal costs and benefits of relational and physical aggression in high school

While recent research using peer ratings demonstrates positive relations between youth's reputations for aggression and popularity, it is not clear whether aggressive youth themselves make these links. Using youth's self‐reports, this study assessed the associations of relational and physical aggression with indicators of both personal gains in peer relations (perceived popularity and receipt of prosocial attention) and personal costs in terms of retaliation or depressive responses (peer victimization and depressive symptoms) in a large sample (n=455) of eighth‐ to tenth‐grade students. Regression analyses reveal that more relationally aggressive youth report more prosocial attention but also more relational (but not physical) victimization. In contrast, more physically aggressive youth report more depressive symptoms and physical (but not relational) victimization. Findings suggest that some costs of aggression (victimization) are higher for boys while others (depressive symptoms) are greater for girls. Group differences were also found for aggressive, victimized, and aggressive/victimized youth compared to the typical low aggressive/low victimized youth. These data suggest that the costs of relational and physical aggression may outweigh benefits except for aggressive non‐victimized boys. Aggr. Behav. 32:409–419, 2006. © 2006 Wiley‐Liss, Inc.     

中国古代辟疫思想的当代启示

通过对以未病先防为主导的中国古代主要辟疫思想及方法的回顾与思考,探讨了其对今天传染病预防的参考价值。认识到在当代传染病预防工作中,借鉴中国古代医学的思想与实践之精粹或许可为当代新发传染病的防治另辟新径,以期能对现代传染病的预治有所启示。     

Social networking site use: Linked to adolescents' social self‐concept,self‐esteem,and depressed mood

Adolescents spend a substantial amount of time using social networking sites (SNSs); however, little is known regarding whether such use is associated with indicators of adjustment. The present study employed a multidimensional measure of SNS use to investigate the link between Australian adolescent SNS use and indicators of adjustment. Youth (N = 1,819, 55% female) from 34 diverse high schools across Western Australia were surveyed. The results showed that frequency of SNS use was linked to higher social self‐concept while investment in SNSs was associated with lower self‐esteem and higher depressed mood. Furthermore, having an SNS was linked to more negative indicators for female adolescents compared with male adolescents, although the link between frequency of use and investment in SNSs to indicators of adjustment was not moderated by gender. The present study highlights the complexity of the relationship between adolescent SNS use and indicators of adjustment, and offers insight into the diverse types of adolescent use of SNSs.     

When You Care Enough to Do Your Very Best: Genetic Counselor Experiences of Compassion Fatigue

Compassion fatigue is a phenomenon that occurs when a caregiver feels overwhelmed by repeated empathic engagement with distressed clients (Figley, 2002). Research demonstrates its existence among nurses, physicians, and mental health professionals, but to date no published study has specifically investigated the nature and prevalence of compassion fatigue among genetic counselors. The present study was an initial attempt to identify and describe the phenomena in genetic counseling by conducting focus group interviews with 12 genetic counselors. Data analysis yielded several themes: a) compassion fatigue occurs and may compromise professional and personal functioning; b) prevalent triggers include delivering bad news and difficult patient issues (e.g., terminal illness, anger, psychopathology); c) effective coping strategies include consulting with colleagues, setting boundaries, and humor; and d) risk factors include personality characteristics and traumatic memories. Training, practice, and research recommendations are provided.     

Psychometric properties of scales in the General Nordic Questionnaire for Psychological and Social Factors at Work (QPSNordic): Confirmatory factor analysis and prediction of certified long-term sickness absence

Psychometric properties, particularly predictive validity, of scales in the General Nordic Questionnaire for Psychological and Social Factors at Work (QPS_Nordic) were assessed. The analysis is confined to the scales in the QPS_Nordic, and 24 of the 26 scales are included. A large group of Swedish county council employees ( n = 3,976; response rate = 65%) participated in a study and were given the QPS_Nordic. Register data for long-term sick leave (>90 days), with diagnosis, were used for predictive analysis. The following main results were obtained: Reliability was generally satisfactory, confirmatory factor analysis indicated good fit, concurrent validity was good, some less often investigated organizational variables predicted sickness absence, and scales were differentially associated with absence due to psychiatric and musculoskeletal disorders. In conclusion, the psychometric testing of the QPS_Nordic so far suggests that it is a good instrument for assessing health-related factors at work.     

Answer comparison in automated question answering

In the context of Question Answering (QA) on free text, we assess the value of answer comparison and information fusion in handling multiple answers. We report improvements in answer re-ranking using fusion on a set of location questions and show the advantages of considering candidates as allies rather than competitors. We conclude with some observations about answer modeling and evaluation methodology, arising from a more recent experiment with a larger set of questions and a greater diversity of question types and candidates.