Timing matters: Negative emotion elicited 5 min but not 30 min or 45 min after learning enhances consolidation of internal-monitoring source memory

Two experiments examined the time-dependent effects of negative emotion on consolidation of item and internal-monitoring source memory. In Experiment 1, participants (n = 121) learned a list of words. They were asked to read aloud half of the words and to think about the remaining half. They were instructed to memorize each word and its associative cognitive operation (“reading” versus “thinking”). Immediately following learning they conducted free recall and then watched a 3-min either neutral or negative video clip when 5 min, 30 min or 45 min had elapsed after learning. Twenty-four hours later they returned to take surprise tests for item and source memory. Experiment 2 was similar to Experiment 1 except that participants, without conducting an immediate test of free recall, took tests of source memory for all encoded words both immediately and 24 h after learning. Experiment 1 showed that negative emotion enhanced consolidation of item memory (as measured by retention ratio of free recall) regardless of delay of emotion elicitation and that negative emotion enhanced consolidation of source memory when it was elicited at a 5 min delay but reduced consolidation of source memory when it was elicited at a 30 min delay; when elicited at a 45 min delay, negative emotion had little effect. Furthermore, Experiment 2 replicated the enhancement effect on source memory in the 5 min delay even when participants were tested on all the encoded words. The current study partially replicated prior studies on item memory and extends the literature by providing evidence for a time-dependent effect of negative emotion on consolidation of source memory based on internal monitoring.     

Science-Based Neurorehabilitation: Recommendations for Neurorehabilitation From Basic Science

ABSTRACT

Neuroscience has fundamentally changed the understanding of learning and memory within recent years. Here, the authors discuss a number of specific areas where they believe new understanding of the CNS from basic science is having a fundamental impact on neurorehabilitation and is leading to new therapeutic approaches. These areas have constituted a basis for development of some basic principles for neurorehabilitation: Optimal rehabilitation should involve (a) active (patient) participation in the training, (b) training that does not only involve many repetitions, but also continues to challenge the skill of the training person, (c) motivation and reward, (d) intensive training and practice over a long time, (e) careful organization of the training in relation to other activities, and (f) incorporation of other potentially beneficial parameters such as sleep and diet. It should in this relation also be pointed out that albeit neurorehabilitation may be predicted to have the most optimal effect early in life and as soon after injury as possible, there is no reason to believe that beneficial effects of training may not be obtained late in life or several years after injury.     

Young children discover how to deceive in 10 days: a microgenetic study

We investigated how the ability to deceive emerges in early childhood among a sample of young preschoolers (Mean age = 34.7 months). We did this via a 10‐session microgenetic method that took place over a 10‐day period. In each session, children played a zero‐sum game against an adult to win treats. In the game, children hid the treats and had opportunities (10 trials) to win them by providing deceptive information about their whereabouts to the adult. Although children initially showed little or no ability to deceive, most spontaneously discovered deception and systematically used it to win the game by the tenth day. Both theory of mind and executive function skills were predictive of relatively faster patterns of discovery. These results are the first to provide evidence for the importance of cognitive skills and social experience in the discovery of deception over time in early childhood.     

Retention interval modulates the effect of negative arousing pictures on recognition memory

This study examined the modulation of retention interval in the effect of emotion as elicited from negative and positive arousing pictures on recognition memory. Participants underwent seven encoding sessions and one testing session. The encoding sessions were separated by certain lengths of intervals such that there were seven levels of time gaps between encoding and testing. In each encoding session, participants learned a list of 30 pictures (including 10 neutral, 10 positive and 10 negative pictures). In the testing session, they were presented with a list of 210 old and 210 new pictures and made “old/new” and “remember/know” judgements. The results showed that negative arousing pictures enhanced overall recognition in the 2-week interval and enhanced recollection in both the 2-week and 3-week intervals. However, neither negative nor positive arousing pictures had any effect on familiarity regardless of retention interval. The current study contributes to the literature by suggesting that longer retention intervals do not necessarily lead to more pronounced effects of negative arousing pictures and that the modulation of retention interval depends on the specific components of recognition memory.     

老年患者的外科治疗决策及围手术期处理

泌尿外科老年患者多,老年患者必然手术并发症多,手术死亡率高.虽然现在泌尿外科近70％的手术已进入了微创时代,手术时间大幅缩减,但是老年患者的临床决策仍常常是个非常纠结的问题,手术要达到什么目的?何时要做适当的放弃?除了充分的围手术期准备,医生要敢于承担,家属要充分理解和合作.     

双气囊小肠镜在小肠相关疾病中的应用进展

小肠及其相关疾病在所有消化道疾病中占有重要地位,对小肠及其相关疾病的诊疗一直存在相当大的困难,常规的内镜检查和治疗方法无法准确诊断和治疗小肠及其相关疾病,例如不明原因消化道出血,小肠肿瘤,胆胰管疾病等。双气囊小肠镜的出现为小肠及其相关疾病的诊疗提供一种全新的方法,内镜下进行小肠疾病治疗,例如小肠出血的止血、息肉的切除、肠腔狭窄扩张等,及各种相关的新技术、新方法层出不穷。本文就对双气囊小肠镜的应用前景和诊疗新进展做一综述。     

大学新生应对方式特点的研究

目的:探讨大学新生应对方式特点。方法:采用应对方式问卷对563名大学新生进行测量。结果:大学新生以使用成熟的应对方式(解决问题、求助)为主;在幻想因子上,性别和专业的主效应显著,女生得分比男生高,文科学生得分高于理科学生得分;在自责因子上,专业主效应显著,文科学生得分高于艺术体育类学生;在求助因子上,生源地的主效应显著,城市大学新生得分高于农村学生。结论:大学新生更多地使用成熟的应对方式;女生比男生更多地使用幻想的应对方式;文科学生比艺术体育类学生更多地使用自责的应对方式;文科学生比理科生更多地使用幻想的应对方式;农村学生比城市学生更少使用求助的应对方式。