An open clinical trial of cognitive-behaviour therapy in children and adolescents with obsessive-compulsive disorder administered in regular outpatient clinics

The aim of the present study was to examine the effectiveness of manual-guided cognitive-behaviour therapy (CBT) for childhood obsessive-compulsive disorder (OCD) administered within three regular, i.e., non-academic, Norwegian outpatient child psychiatric clinics. METHODS: A total of 28 youngsters, aged 8-17 with primary OCD entered the study. Assessment at intake included Norwegian versions of the K-SADS-PL, Children's Yale-Brown Obsessive Compulsive Scale (CY-BOCS), and a measure of OCD-specific functional impairment (Child OCD Impact Scale (COIS)). Therapy consisted of 12 manual-guided sessions with combined individual and family CBT-based interventions and was conducted by psychologists and physicians under training and supervision. Outcome was assessed after treatment and at 3- and 6-month follow-ups by means of the CY-BOCS, the Clinical Global Impression (CGI) and the CGI-Improvement scales, and the COIS. RESULTS: Twenty-four youngsters (86%) completed treatment and were available for the follow-up assessments. Significant improvements were found on all outcome measures after treatment, including a mean symptom reduction on the CY-BOCS of 60.6%, increasing to 68.8% at the 6-month follow-up. Estimates of within-group effect sizes showed strong effects of treatment. CONCLUSION: The results of the present study suggest that manual-guided CBT for childhood OCD can be successfully implemented in non-academic community child psychiatric settings with outcomes in accordance with previous findings from highly specialised university clinics.     

胃肠道双重造影对胃肠道病变诊断的临床思维方法

从方法学原理的角度,通过对胃肠道双重造影征象分析和综合的辩证思维,经过整体和局部相结合,从一般到特殊,由现象到本质,全面客观,纵横联系的认识过程,探讨和研究胃肠道双重造影对胃肠道疾病诊断的科学思维方法,提高、改进影像科医生的临床思雏,对提高医疗水平有着重大的意义。     

脐血干细胞移植治疗肌萎缩侧索硬化伦理问题的思考

肌萎缩侧索硬化症是神经系统一种致死性疾病,目前尚无有效治疗方法,脐血干细胞移植为其生存带来了希望。详细论述了脐血、干细胞与伦理学,肌萎缩侧索硬化与生命伦理学的关系,以及如何在肌萎缩侧索硬化治疗中体现生命伦理学的核心精神。面对脆弱的生命,医务人员、伦理学者和管理部门应该如何为此类疾病患者生命和健康作出应尽的职责。     

论中药品种保护中的法律责任

中药品种保护是不同于专利保护、商标保护的一种新的中药保护模式。它带有浓厚的行政保护色彩。为了更好的保护我国中药知识产权,规范中药的生产和销售行为,应当完善现有的中药品种保护制度,重构中药品种保护中的责任机制,与其他知识产权保护方式相互结合,形成中药知识产权保护体系。     

对手术同意书的法律思考

手术同意书是现代医疗制度中的重要医疗文书.从法律角度看,它具有医务人员职务行为、履行注意义务、履行告知义务及医疗行为合法性等证明效力的法律属性,也具有患者自愿作出选择并授权医方实施手术法律效力,但不具有免除医疗机构责任的效力.由此,需要对手术同意书签字权、内容和形式、手术相关情况的告知过程等加以完善.     

中医药的专利权保护

中医药为中华民族和世界人民的健康做出了重要贡献,但是由于我国对中医药知识产权保护的落后,我国中医药的珍贵知识财富正为外国大公司无偿地攫取.根据中医药自身的特性,对专利保护的适用、调整、改进及补充作了大胆设想,为我国进一步完善中医药的专利法保护提出了建议.     

Personality and prejudice: from Big Five personality factors to facets

Extending our previous research on personality and prejudice, we tested the predictive power of Big Five facet compared with factor scores in three studies. Study 1 (N=170) examined the predictive power of factors and facets when explaining generalized prejudice, a composite of four prejudice types. Study 2 (N=158) focused on sexism and Study 3 (N=80) examined the impact of personality and experimentally manipulated social norm against expressing sexism. Multiple regression analyses showed the strongest facets (Tender-Mindedness and Values) to outperform the strongest factors (Agreeableness and Openness to Experience) in predicting prejudice in all three studies. We discuss the outcome against the background of previous empirical findings and the two major approaches - the personality and the social psychological - to explaining individual differences in prejudice.     

The Role of Gender Identification in Social Dominance Orientation: Mediating or Moderating the Effect of Sex?1

Previous research has shown that people's gender identification correlates with their social dominance orientation (SDO). A question is whether gender identification mediates or moderates the effect of biological sex on SDO. We examined the correlations of sex and gender identification with SDO using the Bem Sex Role Inventory in Study 1 and a gender diagnostic measure in Study 2. Both studies showed that gender identification was significantly associated with SDO. In Study 1, gender identification partially mediated the effect of sex on SDO; and in Study 2, this mediation was complete. There were no indications that gender identification moderated the effect of sex on SDO. The results are discussed against the background of the gender invariance hypothesis of SDO.