Schleiermacher's sermon at Nathanael's grave

The writer provides a translation of the sermon delivered by the German theologian Friedrich Schleiermacher at the grave of his nine-year-old son Nathanael in 1829. An analysis of the sermon explores this most personal statement of Schleiermacher's attitude toward death and reveals the consonance between his theological reflections and the substance of his life.His article first appeared in theJournal of Religion 57 (January 1977):64–75,and is reprinted with the publisher's permission.     

Complainant’s physical attractiveness and juristic judgments of blame and punishment in physical,domestic, and sexual assault scenarios

ABSTRACT

Extralegal factors, including physical attractiveness, may bias juristic opinions. The present study provided 450 university students with hypothetical scenarios of physical, domestic, and sexual assault in which complainant’s attractiveness and other legal and extralegal characteristics were independently varied. Results indicate complainant’s attractiveness mattered in sexual assault scenarios only for guilt of the defendant, but not for physical or domestic assault. Complainant’s attractiveness was not related to perceptions of blameworthiness of complainant or punishment of defendant. Overall, legal factors of injury level, prior offending, and intoxication mattered more than attractiveness or race of the victim. Implications are discussed.     

Turning Up the Heat: Inflammation as a Mechanism Linking Chronic Stress, Depression, and Heart Disease

ABSTRACT— Mounting evidence indicates that chronic stressors and depressive symptoms contribute to morbidity and mortality from cardiac disease. However, little is known about the underlying mechanisms responsible for these effects or about why depressive symptoms and cardiac disease co-occur so frequently. In this article we outline a novel model that seeks to address these issues. It asserts that chronic stressors activate the immune system in a way that leads to persistent inflammation. With long-term exposure to the products of inflammation, people develop symptoms of depression and experience progression of atherosclerosis, the pathologic condition that underlies cardiac disease.     

Subcellular Interactions between Parallel Fibre and Climbing Fibre Signals in Purkinje Cells Predict Sensitivity of Classical Conditioning to Interstimulus Interval

Classical conditioning of the nictitating membrane response requires a specific temporal interval between conditioned stimulus and unconditioned stimulus, and produces an increase in Protein Kinase C (PKC) activation in Purkinje cells. To evaluate whether biochemical interactions within the Purkinje cell may explain the temporal sensitivity, a model of PKC activation by Ca2+, diacylglycerol (DAG), and arachidonic acid (AA) is developed. Ca2+ elevation is due to CF stimulation and IP3 induced Ca2+ release (IICR). DAG and IP3 result from PF stimulation, while AA results from phospholipase A2 (PLA2). Simulations predict increased PKC activation when PF stimulation precedes CF stimulation by 0.1 to 3 s. The sensitivity of IICR to the temporal relation between PF and CF stimulation, together with the buffering system of Purkinje cells, significantly contribute to the temporal sensitivity.     

Subcellular interactions between parallel fibre and climbing fibre signals in purkinje cells predict sensitivity of classical conditioning to interstimulus interval

Classical conditioning of the nictitating membrane response requires a specific temporal interval between conditioned stimulus and unconditioned stimulus, and produces an incrase in Protein Kinase C (PKC) activation in Purkinje cells. To evaluate whether biochemical interactions within the Purkinje cell may explain the temporal sensitivity, a model of PKC activation byCa ²⁺, diacylglycerol (DAG), and arachidonic acid (AA) is developed.Ca ²⁺ elevation is due to CF stimulation and IP3 inducedCa ²⁺ release (IICR). DAG andIP ₃ result from PF stimulation, while AA results from phospholipase A2 (PLA ₂). Simulations predict increased PKC activation when PF stimulation precedes CF stimulation by 0.1 to 3 s. The sensitivity of IICR to the temporal relation between PF and CF stimulation, together with the buffering system of Purkinje cells, significantly contribute to the temporal sensitivity.     

Frames of Reference and Antecedentless Anaphora in Spanish Conversation

This study examines native Spanish speakers’ use of anaphoric pronouns and null subjects in conversational discourse in the absence of coreferential antecedents. It also considers the adequacy of Gundel et al.’s proposal  (Language 69(2):274–307, 1993) that the cognitive status “in focus” corresponds with speakers’ use of minimal referring expressions (i.e., unstressed pronouns and zeros). Analysis of naturally occurring Spanish conversation shows how the felicitous use and interpretation of non-canonical (antecedentless) anaphoric pronouns and null subjects are possible due to the activation of underlying cognitive frames that are shared by the interlocutors. Furthermore, the speaker’s mention of a referent, dubbed a “neighborhood antecedent” by Langacker (Conceptual grouping and pronominal anaphora, in: Fox (ed) Studies in anaphora, Cambridge University Press, Cambridge, 1996), and the information “filled in” over the course of the conversation on account of the activation of relevant cognitive frames, both license and disambiguate the non-canonical anaphoric relations.     

When propriety is improper

Philosophical Studies - We argue that philosophers ought to distinguish epistemic decision theory and epistemology, in just the way ordinary decision theory is distinguished from ethics. Once one...