Inhibition of the LH Surge by Restraint Stress in Cyclic Rats: Studies on the Role of GABAA and GABAB Receptors

There is evidence that stress can alter the activity in the brain of gamma-aminobutyricacid (GABA), a neurotransmitter that has been implicated in the regulation of LH secretion. In the present study the role of GABA in the restraint stress-induced inhibition of the LH surge was investigated in the intact cyclic rat. Intracerebroventricular (icv) administration of the GABAA receptor agonist muscimol (0.1, 0.5 or 1 μg) 5 min before the presumed onset of the pro-oestrous LH surge (at 0900 h) caused a dose dependent suppression of the surge. A single dose of the GABAB receptor agonist baclofen (1 μg; icv) injected at 0855 h postponed the onset of the LH surge, and repeated injections at 0855 and 1130 h suppressed the surge. These data indicate that GABA-ergic activity in the brain can inhibit the LH surge in the cyclic rat via GABAA and GABAB receptors. Pro-oestrous rats were subjected to 5 hrs of restraint starting at 0855 h. Pretreatment with the GABAA receptor antagonist bicuculine (1 μg; icv) at 0840, 0940 and 1040 h or pretreatment with the GABAB receptor antagonist phaclofen (10 μg; icv) at 0840 h were ineffective in preventing the restraint-induced inhibition of the LH surge. The results suggest that GABAA and GABAB receptors are not involved in the inhibitory effect of restraint stress on the LH surge.     

Repetition,cuing, and state-dependent memory

Two experiments examined the effects of several types of repetition on state-dependent memory for conceptually categorized words. In both experiments, compatibility between pharmacological states at encoding and at retrieval facilitated the uncued recall of nonrepeated categories but had no appreciable effect on the recall of words within recalled categories. In both experiments, compatibility between encoding/retrieval states failed to facilitate the uncued recall of repeated categories li.e., categories whose names and/or exemplars were presented at least twice, in a constant or variable order, and with substantial spacing between successive presentations). And again, in both experiments, the level of uncued recall was higher for repeated than for nonrepeated categories, irrespective of the compatibility or incompatibility of encoding/retrieval states. These findings, together with other relevant observations reported in the literature, suggest that repetition in general, and repetition of category names in particular, influences recall in much the same ways as does explicit cuing with category names: It enhances the accessibility of higher order units, as reflected in uncued category recall, and it diminishes to the extent to which access to these units is state dependent.     

Prevocational Experience and Postentry Behavior: Occupational Influences on Job Attitudes and Turnover

The effect of prevocational contact on postentry behavior was studied using a sample of staff nurses. The results indicated that those nurses who had prevocational contact with the nursing occupation had different conceptions of the nursing role and more positive work attitudes than those who did not have prevocational contact with the profession. The groups. however, did not differ with respect to turnover.     

Dimension integration: Testing models without trade-offs

This paper tests a behavioral property called dimension integration. The test evaluates models, such as lexicographic semi-orders and the priority heuristic, which assume that a person uses only one dimension at a time. It provides a way to compare such models against those that assume a person combines information from different dimensions. The test allows one to test the hypothesis that different people use different lexicographic semi-orders with different threshold parameters. In addition, by use of a “true and error” model, it is possible to “correct” for unreliability of choice in order to estimate the proportions of participants who show different response patterns that can be classified as integrative or not integrative. An experiment with 260 participants was conducted in which people made choices between two-branch gambles. The aggregate results violate the priority heuristic and six lexicographic semi-orders. The data also refute the theory that people use a mixture of these lexicographic semi-orders. In addition, few individuals appear to show response patterns consistent with non-integrative models. Instead, they show that most individuals show patterns consistent with the hypothesis that they combine information between dimensions.     

Positive contrast obtained in reacquisition following interpolation of nonreinforced or partially reinforced trials

Two experiments investigated the effects of shifting from either nonreinforcement or partial reinforcement (PRF) to continuous reinforcement conditions (CRF). In the first experiment, three groups of rats were given food reinforcement under CRF conditions in a runway followed by regular extinction trials (RE), extinction trials where Ss were delayed for 30 sec before entering the empty goal box (DE), or CRF trials where Ss were delayed for 30 sec before entering the baited goal box (DF). Then all Ss were run on the delayed reinforcement condition (DF). In the final delayed reinforcement condition, group DE ran significantly faster than group DF, reflecting positive contrast. In the second experiment, four groups of rats were trained in a runway to receive either 4% or 18% sucrose reinforcers under either PRF or CRF conditions. Then all Ss were transferred to a Skinner box and bar presses were continuously reinforced, with each S continuing to receive the same sucrose concentration as before. The former PRF Ss, regardless of the reinforcer, bar pressed at a significantly higher rate in the Skinner box than the former CRF Ss. The evidence seemed to favor the view that the effectiveness of a reinforcer is not an absolute, unchanging quantity but rather depends on the historical context in which the reinforcer occurs.     

Using contextual effects to derive psychophysical scales

This paper presents a functional measurement analysis of Parducci’s range-frequency theory. The theory provides a basis for (1)finding context-invariant psychophysical scales, (2)establishing the validity of rating scales, and (3) explaining contextual effects in judgment. In an experimental illustration, Ss judged the magnitude of numerals in nine different distributions. All data were used to obtain the psychophysical function for numerals and also to test the model. The large contextual effects were consistent with the model. Quantitative tests of fit supported the equal-interval assumption of the category scale. The psychophysical function appeared nearly linear but with a significant negative acceleration. The data were shown to be qualitatively inconsistent with generalizations of Helson’s theory of adaptation level and Johnson’s correlation-regression theory. They supported Parducci’s range-frequency theory and illustrated how it could be used to factor out contextual effects from effects of stimulus magnitude. Extensions of the range-frequency approach are also discussed.     

Judgments of proportions

This study investigated the processes that underlie estimates of relative frequency. Ss performed 4 tasks using the same stimuli (squares containing black and white dots); they judged "percentages" of white dots, "percentages" of black dots, "ratios" of black dots to white dots, and "differences" between the number of black and white dots. Results were consistent with the theory that Ss used the instructed operations with the same scale values in all tasks. Despite the use of the correct operation, Ss consistently overestimated small proportions and underestimated large proportions. Variations in the distributions of actual proportions affected the extent to which Ss overestimated small proportions and underestimated large proportions in the direction predicted by range-frequency theory. Results suggest that proportion judgments, and by analogy probability judgments, should not be taken at face value.     

Distributional theories of impression formation

This paper examines theories of impression formation which represent stimulus information as distributions on subjective dimensions rather than points along a continuum. These theories explain why unfavorable information often overrides favorable information. Subjects were asked to imagine hypothetical persons described by single adjectives or adjective combinations and to estimate the probability that each person would have various degrees of likeableness. Three models were considered to describe how the likeableness distribution for the adjective combination depends on the distributions of the single adjectives. All three models assume that the mean of the distribution for the adjective combination is described by the equal probability criterion which, for symmetric distributions, implies a weighted average of the single adjective means with weights inversely proportional to their standard deviations. The models can be distinguished on the basis of the standard deviations of the adjective combinations. Estimated standard deviations of the single unfavorable adjectives were smaller than those for the single favorable adjectives. Furthermore, the standard deviation associated with an adjective combination tended to fall between the standard deviations of the single adjectives, consistent with the horizontal averaging model.