Somatoforme Störungen bei ambulanten dermatologischen Patienten

Zusammenfassung In der vorliegenden Studie wurde die Häufigkeit somatoformer Symptome in einer dermatologischen Universitätsambulanz untersucht. An der Studie nahmen n=195 Patienten teil, die Screeningfragen zu somatoformen, dermatologischen und depressiven Symptomen ausfüllten. Zusätzlich wurde eine dermatologische Beurteilung der Symptome hinsichtlich der Ätiologie erfasst. Danach wiesen 26,2% der Patienten Hinweise auf eine somatoforme Störung auf; am häufigsten waren somatoforme Schmerzstörung (16,9%) und körperdysmorphe Störung (15,4%). Unter den spezifischen dermatologischen Symptomen wurde Juckreiz besonders häufig (10,3%) als somatoform klassifiziert. Der Anteil von Patienten mit erhöhten depressiven Beschwerden lag bei 17,3%. Die Ergebnisse sprechen für eine erhöhte Prävalenz somatoformer Störungen bei dermatologischen Patienten. Die Identifizierung und psychotherapeutische Versorgung dieser Patientengruppe sollte in der dermatologischen Routineversorgung mehr Beachtung finden.     

Busy doing nothing: Evidence for nonaction-effect binding

Research on voluntary action has focused on the question of how we represent our behavior on a motor and cognitive level. However, the question of how we represent voluntary not acting has been completely neglected. The aim of the present study was to investigate the cognitive and motor representation of intentionally not acting. By using an action-effect binding approach, we demonstrate similarities of action and nonaction. In particular, our results reveal that voluntary nonactions can be bound to an effect tone. This finding suggests that effect binding is not restricted to an association between a motor representation and a successive effect (action-effect binding) but can also occur for an intended nonaction and its effect (nonaction-effect binding). Moreover, we demonstrate that nonactions have to be initiated voluntarily in order to elicit nonaction-effect binding.     

Spider-Phobic Children Do Not React with Differential Skin Conductance Responses to Masked Phobic Stimuli

In the present study, spider-phobic children (N = 22) were exposed to subliminal presentations of spiders, snakes, and mushrooms, while skin conductance responses (SCRs) were measured. In addition, pre- and post-treatment symptom severity data were obtained. As a group, spider-phobic children did not react with differential SCRs to masked phobic pictures. In addition, no convincing evidence was found to suggest that individual variation in differential SCRs to phobic stimuli is linked to pre-treatment symptom severity or therapy outcome. These findings cast doubts on the idea that phobics' phenomenal experience of their fear as irrational and uncontrollable is a result of pre-attentive physiological fear activation.     

Hiring bias and the disabled interviewee: Effects of manipulating work history and disability information of the disabled job applicant

Ninety MBA students were randomly assigned to one of six experimental conditions in a 3(levels of disability) × 2(levels of employment history) design. Levels of disability (Physical, Psychiatric, and No Disability) and levels of employment history (Good and Poor) were manipulated by giving the subjects bogus information on a job application form prior to hearing a taped job interview. Subjects then rated the quality of the interview and stated the probability that they would hire the interviewee. Evaluations of the interview and hiring probabilities were different between the experimental groups. Implications and suggestions for future research are discussed.     

From the left to the right: How the brain compensates progressive loss of language function

In normal right-handed subjects language production usually is a function oft the left brain hemisphere. Patients with aphasia following brain damage to the left hemisphere have a considerable potential to compensate for the loss of this function. Sometimes, but not always, areas of the right hemisphere which are homologous to language areas of the left hemisphere in normal subjects are successfully employed for compensation but this integration process may need time to develop. We investigated right-handed patients with left hemisphere brain tumors as a model of continuously progressive brain damage to left hemisphere language areas using functional neuroimaging and transcranial magnetic stimulation (TMS) to identify factors which determine successful compensation of lost language function. Only patients with slowly progressing brain lesions recovered right-sided language function as detected by TMS. In patients with rapidly progressive lesions no right-sided language function was found and language performance was linearly correlated with the lateralization of language related brain activation to the left hemisphere. It can thus be concluded that time is the factor which determines successful integration of the right hemisphere into the language network for compensation of lost left hemisphere language function.     

A role for Synapsin in associative learning: the Drosophila larva as a study case

Synapsins are evolutionarily conserved, highly abundant vesicular phosphoproteins in presynaptic terminals. They are thought to regulate the recruitment of synaptic vesicles from the reserve pool to the readily-releasable pool, in particular when vesicle release is to be maintained at high spiking rates. As regulation of transmitter release is a prerequisite for synaptic plasticity, we use the fruit fly Drosophila to ask whether Synapsin has a role in behavioral plasticity as well; in fruit flies, Synapsin is encoded by a single gene (syn). We tackled this question for associative olfactory learning in larval Drosophila by using the deletion mutant syn^97CS, which had been backcrossed to the Canton-S wild-type strain (CS) for 13 generations. We provide a molecular account of the genomic status of syn^97CS by PCR and show the absence of gene product on Western blots and nerve-muscle preparations. We found that olfactory associative learning in syn^97CS larvae is reduced to ~50% of wild-type CS levels; however, responsiveness to the to-be-associated stimuli and motor performance in untrained animals are normal. In addition, we introduce two novel behavioral control procedures to test stimulus responsiveness and motor performance after “sham training.” Wild-type CS and syn^97CS perform indistinguishably also in these tests. Thus, larval Drosophila can be used as a case study for a role of Synapsin in associative learning.     

Perceptions of self-oriented and other-oriented help-providers

Two studies were conducted to assess the relationship between an individual's self-described motivation for being a help-provider (i.e., a lawyer in Study 1 and a physi-cian in Study 2) and college undergraduates' perceptions of, and desire to seek assis-tance from, that help-provider. The major findings were incongruent with the notion inferred from the helping literature that altruistically motivated help-providers would be consistently evaluated more favorably than, and preferred over, egoistically moti-vated help-providers. Specifically, whereas the other-oriented help-providers were rated as more likable, honest, and less devious than the self-oriented help-providers, the self-oriented help-providers were rated as more ambitious, competent, and as earning more money than the other-oriented help-providers. Moreover, although the participants' “desire to hire” a particular help-provider was found to be associated with: (1) their perceptions of the help-provider's characteristics (Studies 1 and 2), (2) their own self-reported characteristics (Study 1), and (3) their anticipated affective state prior to seeking assistance (Studies 1 and 2), no clear relation was found in either study between the help-provider's motivation and the participants' desire to seek assistance from that help-provider. In contrast to the ambivalence demonstrated in response to the altruistically and egoistically motivated professional help-providers in Studies 1 and 2, participants in a preliminary study of perceptions of “everyday” helpers demonstrated a clear preference for altruistically motivated assistance (al-though these participants' evaluations were found to be influenced by the closeness of the relationship between the helper and recipient, the type of help provided, the participants' gender, and the gender of the helper-recipient dyad). Considered to-gether, the pattern of results suggests the broad range of situational and individual difference variables that may affect perceptions of, and reactions to, self-oriented and other-oriented help-providers.     

Validation of a category system for arguments in conflict discourse

Theories of individuation predict systematic differences in argumentative behavior between adolescent girls and their mothers. In order to reveal the nature and functions of this kind of discourse, two studies were carried out on 110 mother-daughter pairs. The second study (n=80) replicated and extended the first study (n=30) on an independent sample. The mother-daughter pairs were asked to discuss a subject that had recently been at issue between them. To assess the argumentative behavior, a category system was developed that reflects the functional character of utterances in discourse. The aim of the research was to test the reliability and validity of the category system. Daughters are assumed to verbalize their own needs and preferences to increase the differences to the mother, and to weaken or reject the mother's arguments in an effort to resist control. Mothers, on the other hand, are supposed to exert control over the behavior of their daughters but do so within bounds of mutuality. This should lead to verbal initiatives and attempts to explain, support and modify their positions and arguments. The data showed high reliability of the categorization of arguments. The categories also differentiated between mothers and daughters. Daughters were more likely to try to weaken and reject (and accept) the mother's arguments and to state preferences while mothers tried to support and explain their positions and to retain control by initiating questions and arguments to which the daughters responded.     

Reinstatement of fear in humans: autonomic and experiential responses in a differential conditioning paradigm

The present study investigated reinstatement of fear in humans using an aversive differential conditioning paradigm. Two neutral human face pictures were presented during habituation, acquisition, extinction, and postreinstatement phases. One picture served as a conditioned stimulus (CS) reinforced by an unconditioned stimulus (US) in the form of electrical stimulation (CS+) and the second picture as a control stimulus that was never reinforced (CS-). The prediction that in a reinstatement manipulation a previously extinguished fear response in humans can be reinstated in a reinstatement group by the mere presentation of three unpredicted electrical stimulations (USs) was tested. Participants in the control group were not exposed to unpredicted USs and no reinstatement effect was expected. Outcome measures included subjective US expectancy ratings and skin conductance responses. Results showed non-selective return of the fear response due to fear recovery associated with both CSs (CS+/CS-) in the reinstatement group. Unexpected fear recovery was observed for both CSs (CS+/CS-) in control participants. Results are discussed with respect to context conditioning, fear generalisation, and anxiety-related cognitive mechanisms underlying fear recovery after extinction.