EEG theta phase coupling during executive control of visual working memory investigated in individuals with schizophrenia and in healthy controls

In healthy humans, it has been shown that executive functions are associated with increased frontal-midline EEG theta activity and theta phase coupling between frontal and posterior brain regions. In individuals with schizophrenia, central executive functions are supposed to be heavily impaired. Given that theta phase coupling is causally involved in central executive functions, one would expect that patients with an executive function deficit should display abnormal EEG theta synchronization. We therefore investigated executive functioning in 21 healthy controls and 21 individuals with schizophrenia while they performed a visuospatial delayed match to sample task. The task required either high executive demands (manipulation of content in working memory [WM]) or low executive demands (retention of WM content). In addition, WM load (one vs. three items) was varied. Results indicated higher frontal theta activity for manipulation processes than for retention processes in patients with schizophrenia, as compared with healthy controls, independently of WM load. Furthermore, individuals with schizophrenia revealed a reduction in theta phase coupling during early stages of the delay period for retention, as well as for manipulation processes at high-WM loads. Deviations in theta phase coupling in individuals with schizophrenia were mainly characterized by aberrant fronto-posterior connections, but also by attenuated posterior connections during manipulation of high-WM load. To conclude, fronto-parietal theta coupling seems to be substantially involved in executive control, whereas frontal theta activity seems to reflect general task demands, such as deployment of attentional resources during WM.     

Treating chronic tinnitus: comparison of cognitive-behavioural and habituation-based treatments

Using a randomized control group trial the long-term efficacy of a habituation-based treatment as conceived by Jastreboff, and a cognitive-behavioural tinnitus coping training were compared. An educational intervention was administered as a control condition. Both treatments were conducted in a group format (habituation-based treatment, 5 sessions; tinnitus coping training, 11 sessions). Educational intervention was delivered in a single group session. Patients were categorized according to their level of disability due to tinnitus (low, high), age and gender and then randomly allocated to the treatment conditions (habituation-based treatment, n = 30; tinnitus coping training, n = 27; educational intervention, n = 20). Data assessment included follow-ups of up to 21 months. Several outcome variables including disability due to tinnitus were assessed either by questionnaire or diary. Findings reveal highly significant improvements in both tinnitus coping training and habituation-based treatment in comparison with the control group. While tinnitus coping training and habituation-based treatment do not differ significantly in reduction of tinnitus disability, improvement in general well-being and adaptive behaviour is greater in tinnitus coping training than habituation-based treatment. The decrease in disability remains stable throughout the last follow-up in both treatment conditions.     

Affect regulation and food intake in bulimia nervosa: emotional responding to food cues after deprivation and subsequent eating

Emotional responding to salient food cues and effects of food deprivation and consumption were investigated in 32 women with bulimia and 32 control women. One half of each group was food deprived before viewing unpleasant, neutral, pleasant, and food-related pictures. Then participants could eat from a buffet before viewing a parallel picture set. Women with bulimia showed a substantial potentiation of startle responses during viewing of food cues relative to control women. This startle potentiation was attenuated by food deprivation and augmented by increased food consumption. These data support the affective regulation model suggesting that food cues prompt negative affective states in women with bulimia, who are overwhelmed by fasting. The resulting deprivation increases the incentive value of food cues and may thus trigger binge eating.     

Picture-object recognition in pigeons: evidence of representational insight in a visual categorization task using a complementary information procedure

Success in tasks requiring categorization of pictorial stimuli does not prove that a subject understands what the pictures stand for. The ability to achieve representational insight is by no means a trivial one because it exceeds mere detection of 2-D features present in both the pictorial images and their referents. So far, evidence for such an ability in nonhuman species is weak and inconclusive. Here, the authors report evidence of representational insight in pigeons. After being trained on pictures of incomplete human figures, the birds responded significantly more to pictures of the previously missing parts than to nonrepresentative stimuli, which demonstrates that they actually recognized the pictures' representational content.     

Physiological and behavioral parameters of infants' categorization: changes in heart rate and duration of examining across trials

This report investigates the relations between duration of examining and heart rate (HR) across several trials of an object-examination task. A total of N= 20 11-month-olds were familiarized with a sequence of 10 different exemplars from the same global category (animals or furniture) before they received an exemplar from the contrasting category at test. Consistent with previous findings, HR was lower during states of focused attention (i.e. examining) than during states of casual attention (i.e. looking) or non-looking. Over the familiarization trials, examining stayed about the same, while mean HR increased. At test, examining increased and mean HR decreased, indicating that infants focused their attention on the out-of-category object. Psychophysiological and behavioral measures of attention were systematically related over trials, suggesting that heart rate provides a suitable objective measure to study infants' categorization performance in object-examination tasks.     

Fear of the new? Geckos hesitate to attack novel prey,feed near objects and enter a novel space

Animal Cognition - Neophobia, the fear of novelty, is an ecologically important response which enables animals to avoid potentially harmful situations. Neophobia is a cognitive process by which...     

Specialist, physical therapy and social work management status of older children and adolescents with cerebral palsy

In face of catamnestic examinations at a group of 61 older children and juveniles with infantile cerebral palsy we can see, that an optimal attendance by medical specialists, physiotherapists and social workers is not reached yet in each case. 39 patients (64 p.c.) are provided by a specialist regularly, 35 patients (57.4 p.c.) regularly get a physiotherapeutic treatment and 33 patients (54.1 p.c.) are often only sporadically attended by social workers. Serious disabled children, who are nursed only in their families, bring particular problems. In the authors opinion a decisive improvement of attendance is possible. For that purpose a more intensive work of "Dispensaries for disabled children and juveniles" in connexion with a consistent utilization of the socialist legislation is necessary.     

Theory-of-mind, cognitive development, and children's interpretation of anxiety-related physical symptoms

The present study investigated developmental patterns in children's interpretation of anxiety-related physical symptoms and emotional reasoning, and to what extent these phenomena are influenced by children's level of cognitive development. A large sample of 4-13-year-old children (N=358) were exposed to vignettes in which the presence and absence of physical symptoms was systematically varied. In addition, children completed a series of conservation tasks and a theory-of-mind-test. Results demonstrated that from the age of 7, children were increasingly able to link physical symptoms to anxiety. Furthermore, cognitive development appeared to enhance children's ability to interpret physical symptoms as a sign of anxiety. Further, children's tendency to infer danger from vignettes with physical symptoms (i.e., emotional reasoning) was already prominent in 4-6-year-olds. The implications for physical symptom-based theories of childhood anxiety are briefly discussed.     

The Effects of Non-invasive Brain Stimulation on Impulsivity in People with Mental Disorders: a Systematic Review and Explanatory Meta-Analysis

Neuropsychology Review - Impulsivity is a multi-faceted construct that underpins various mental health disorders. Impulsive behavior exacts a substantial health and economic burden, hence the...