Measuring Child Mental Health Status for Services Research

Epidemiological studies of the prevalence of mental health disorders typically contain multiple measures of mental health, using different instruments and different informants (child, parent, and interviewer). We used the Methods for the Epidemiology of Child and Adolescents Mental Disorder (MECA) study of U.S. youth to assess the effects of employing a range of these measures in mental health services research. We examined the effect of including various measures of mental health status in regressions of income on mental health service use. The estimated effect of income on service use varied widely, depending on the measure of mental health status used. Some measures of mental health status have little explanatory power in service use regressions. Measures of mental health status based on parental assessment of impairment or need, such as the Columbia Impairment Scale, are less costly to collect and also have good explanatory power, but are more strongly correlated with income. The Non-Clinician Child Global Assessment Scale (NC-CGAS) performs best in terms of explanatory power and correlation with income. Higher income parents appeared to judge behaviors differently from lower income parents, so analyses based on measures derived from parental report may lead to an understatement of the effect of income on service use.     

Dexamethasone Does Not Prevent Seven-Day ADX-Induced Apoptosis in the Dentate Gyrus of the Rat Hippocampus

Long-term adrenalectomy (ADX) is known to result in apoptosis within the dentate gyrus of the rat hippocampus. While the underlying mechanism is still unclear, adrenal steroids appear to play a pivotal role in granule cell survival, as administration of the mineralocorticoid receptor (MR) agonists, corticosterone and aldosterone, to ADX rats results in protection against the ADX-induced effect. The consequence of administration of the glucocorticoid receptor (GR) agonists, dexamethasone and RU28362, however, is less clear, and either complete or only partial protection for the ADX animal has been reported. This study investigated further the role played by GR in the degenerative process. After establishing the characteristics of seven-day ADX-induced apoptosis in the young male Wistar rat, the effect of chronically-implanted, subcutaneous pellets containing various doses of dexamethasone and corticosterone, on ADX-induced apoptosis was studied. Both high and low doses of corticosterone were found to be protective. In contrast to some other studies, however, neither dose of dexamethasone had any obvious protective effect and rather seemed to increase apoptosis in dentate gyrus of intact animals. Intracerebroventricular infusion of dexamethasone for seven days was also found to be ineffective in preventing apoptosis, demonstrating that it is occupation of MR, rather than GR, which is crucial to dentate gyrus granule cell survival.     

Effects of stimulus duration and ISI on accuracy and transference errors in pictorial recognition

The influence of stimulus duration and ISI on accuracy of recognition for two-part configurations was investigated in two experiments. A six-alternative forced-hoice recognition procedure is described that tested (1) subjects’ ability to recognize correct or partially correct stimuli, and (2) their tendencies to make transference errors. Subjects were significantly more accurate in recognition of pictorial components when given a longer (2-sec) rather than a shorter (.5-sec) exposure to stimuli, with ISI held constant (.5 sec). There was no beneficial effect on recognition of pictorial components when ISI was lengthened from .5 to 2 sec Iwith a .5-sec stimulus duration) or from .5 to 1.5 to 7 sec Iwith a 2-sec stimulus duration). The total time hypothesis received no support, since when two groups were given the same total time (2.5 sec for stimulus duration plus ISI), the group given the longer 12-sec) stimulus duration was significantly more accurate in partial recognition than a group given a longer 12-sec) ISI. There was a high incidence of transference errors in all experimental groups, although subjects’ ability to distinguish old stimuli from distractors made by recombining parts from different targets was not affected by any of the temporal manipulations. It appeared that, although length of stimulus duration determines the number of components encoded from a picture, the encoding of information that integrates these components into a whole does not require additional processing time.     

Ethical issues in communicating science

Most of the publicized work on scientific ethics concentrates on establishing professional norms and avoiding misconduct. The successful communication of science is the responsibility of all involved in the process. In one study, the increased incidence of autism and other social developmental disorders in males was investigated by examining individuals with Turner's syndrome (XO females). In the national newspaper this became "Genetic X-factor explains why boys will always be boys". The steps by which a study on developmental disorders, published in a highly prestigious journal, was transformed into an article in the science section which 'explained' the socially expected gender-based behavior of genetically normal children are fascinating and, unfortunately far too typical. The scientists wrote an excellent article that has just one sentence at the end that hesitantly suggests that the findings might, with further study, have some relevance to understanding normal behavior. The general interest article in the front of the journal gave a good account of the research, but suggested more strongly that there could be an in-built biological dimorphism in social cognition. This was misrepresented in the press as proof of gender differences that "undermines the trend towards sexual equality", and both illustrates cultural bias and provides fodder for feminist critiques of science. The study has been made to appear to be biased in favor of justifying the social structure of society, and yet it was the translation from the scientific study to national news that produced this transformation to biased genetic determinism. It is poor communication of the actual science, coupled with a lack of skepticism on the part of the public, that contributes to such a misapplication of science. Scientists should resist the urge to generalize their results to make them more compelling. The science community should not allow misconstructions of scientific facts to go unchallenged. Journalists, for both the scientific publication and the newspaper, should resist the inclination to embellish the finding with social significance that is not present. For their part, readers must be doubly skeptical of any finding that appears to underwrite any current social hierarchy. We are all responsible for a communication and interpretation of science that is as accurate and socially responsible as possible.     

Correspondence between statistically derived behavior problem syndromes and child psychiatric diagnoses in a community sample

The correspondence between Diagnostic and Statistical Manual (3rd ed.) (DSM-III) diagnoses and statistically derived syndromes was examined within a community sample of children and adolescents in Puerto Rico. Specifically, the extent to which behavior dimensions, derived from the Child Behavior Checklist and the Youth Self-Report, corresponded to psychiatric diagnoses, derived from parent and child versions of the Diagnostic Interview Schedule for Children, was examined. The alternative approaches for assessing psychopathology in children and adolescents were compared against external validators. The results indicated a meaningful convergence between DSM-III diagnoses and statistical syndromes; however, a one-to-one correspondence did not emerge. Little evidence was found for diagnostic thresholds. There was no evidence of the superiority of either the statistically derived syndromes or the DSM-III diagnoses. The incorporation of a measure of impairment improved the validity of both approaches. Adding parental reports to the selfreports of adolescents yielded little gain in the validity of either the statistical or diagnostic approach. The implications for the definition and assessment of child and adolescent disorders are discussed.This research was supported by grant MH 38821 from the National Institute of Mental Health.The authors wish to acknowledge Glorisa Canino, Ph.D., and Maritza Rubio-Stipec, M.A., of the University of Puerto Rico, co-investigators in the epidemiologic project and to Barbara Bettes, Ph.D. for her contribution to preliminary analyses for this manuscripl. Portions of this paper were presented at the 38th Annual Meeting of the American Academy of Child and Adolescent Psychiatry, San Francisco, October 1991.     

Competition, cooperation, satisfaction, and the performance of complex tasks among air force cadets

Forty-eight U.S. Air Force Academy cadets were studied to examine the effects of individual attitudes and organizational reward structures on the performance of a complex, integrative task. An attitudinal survey was used to measure each subject’s preference for cooperative or competitive situations. Distinctly different group environments were created by giving four groups of six subjectscompetitive instructions and another four groupscooperative instructions. The performance criterion was the “sum” score across eight trials of a complex arcade-type computer game which required one subject to control horizontal movement and another to control vertical movement. Although neither attitude nor reward structure alone influenced performance, their interaction was found to be very significant; subjects performed poorly when the reward structure did not match their individual orientation. Implications for military and professional training programs are discussed.     

Strong Necessitarianism: The Nomological Identity of Possible Worlds

Dispositional essentialism, a plausible view about the natures of (sparse or natural) properties, yields a satisfying explanation of the nature of laws also. The resulting necessitarian conception of laws comes in a weaker version, which allows differences between possible worlds as regards which laws hold in those worlds and a stronger version that does not. The main aim of this paper is to articulate what is involved in accepting the stronger version, most especially the consequence that all possible properties exist in all worlds. I also suggest that there is no particularly strong reason for preferring the weaker to the stronger version. For example, Armstrong's instantiation condition on universals entails that according to strong necessitarianism every property is instantiated in all possible worlds. But first we do not need to accept Armstrong's instantiation condition, in part because his arguments for it are forceful only for a contingentist about laws and properties. Secondly, even if we do accept the condition, the consequence that all properties are instantiated is not itself contradictory, so long as any form of necessitarianism holds. Strong necessitarianism is prima facie counter‐intuitive. But for that matter so is weak necessitarianism. Accepting either weak or strong necessitarianism requires denying the force of intuition in this area. And indeed we have every reason to deny the force of intuition and its primary source, imagination, concerning modal facts.     

库恩的错误转向

一、库恩的一份遗产 托马斯·库恩的遗产呈现出一种自相矛盾的现象.尽管库恩对20世纪最后的30余年的科学哲学是最有影响力的,但事实却是,在科学哲学中并没有明确的库恩学派.而且最有库恩特色的论题(不可通约性论题)不再被认为像库恩所宣称的那样,是具有哲学意义的论题了.