Depletion of brain norepinephrine with DSP-4 does not alter acquisition or performance of a radial-arm maze task

The acquisition of a radial-arm-maze task was unimpaired following administration of DSP-4, a selective noradrenergic neurotoxin. Maze performance remained unaffected when 5- or 30-min delays were imposed between the fourth and the fifth arm selection. Neurochemical analysis performed 90 days after injection revealed that DSP-4 significantly decreased concentrations of norepinephrine in the hippocampus, cortex, and cerebellum. The regional concentrations of dopamine and serotonin were not affected. These data are consistent with previous reports demonstrating that depletion of brain norepinephrine does not impair spatial learning and memory.     

The Influence of Openness to Experience on Perceived Employee Creativity: The Moderating Roles of Individual Trust

In this paper, we explain the influence of co‐worker trust on the effect of employees' openness to experience on their perceptions of their own creativity. We surveyed 199 working professionals in Ireland and found that openness to experience was positively associated with both employees' perceptions of their radical creativity and incremental creativity. In addition, the relationship between openness to experience and incremental creativity was negatively moderated by cognition‐based trust in his or her co‐worker. In conclusion, we discuss the theoretical and managerial implications of our findings and highlight directions for future research.     

Caring: A Pluralist Account

In this paper, I argue that care ethics should be understood as a form of value pluralism. Writers on the ethics of care tend not explicitly to address issues in the theory of value, although much of what has been written about care ethics may be taken to suggest that it endorses some form of value monism. I argue against this conception of care ethics by showing that the practical reality of caregiving is more accurately represented by a pluralist account of value. Practices of care are plausibly guided by a number of distinct and potentially conflicting values. These include quality of life, autonomy, dignity, personal development, and the value of nurturant relationships. Whilst caring takes each of these values to be important in its own right, they are not always jointly realisable, and carers are sometimes forced to promote one such value at the expense of another. The possibility of conflict between values is, of course, precisely what a pluralist conception of value tells us to expect. In this respect, then, value pluralism more faithfully reflects the reality of caregiving than does value monism, and care ethicists ought for this reason to endorse it.     

Disclosure on Campus: Students’ Decisions to Tell Others About Unwanted Sexual Experiences,Intimate Partner Violence,and Stalking

The scope of student victimization occurring on college campuses is problematic, drawing the attention of researchers and campus officials. While most researchers of the disclosure of these unwanted experiences tend to examine just 1 form of victimization, a direct comparison of the disclosure of different types of campus victimization within a singular study is missing in the literature. The current study aimed to address this issue by examining 4 types of victimization experiences (unwanted sexual contact, unwanted sexual intercourse, intimate partner violence, and stalking) in a college population. A common set of possible predictors of disclosure were examined, including both demographic (e.g., gender, race, age) and situational factors (e.g., alcohol use, level of fear, relationship with perpetrator). While patterns of similarity across all victimization experiences emerged, the impact of gender, race, age, and alcohol use on disclosure decisions varied substantially by victimization type. The findings of this study address the gap in the current literature by providing a comparison and contrast of the influence of predictors across different types of victimization. Furthermore, the findings provide needed information that could help colleges and universities develop ways to encourage support-seeking and reporting among students.     

Uterus Transplantation: The Ethics of Using Deceased Versus Living Donors

Research teams have made considerable progress in treating absolute uterine factor infertility through uterus transplantation, though studies have differed on the choice of either deceased or living donors. While researchers continue to analyze the medical feasibility of both approaches, little attention has been paid to the ethics of using deceased versus living donors as well as the protections that must be in place for each. Both types of uterus donation also pose unique regulatory challenges, including how to allocate donated organs; whether the donor / donor's family has any rights to the uterus and resulting child; how to manage contact between the donor / donor's family, recipient, and resulting child; and how to track outcomes moving forward.     

The Doctor(s) in House: An Analysis of the Evolution of the Television Doctor-Hero

The medical drama and its central character, the doctor-hero have been a mainstay of popular television. House M.D. offers a new (and problematic) iteration of the doctor-hero. House eschews the generic conventions of the "television doctor" by being neither the idealized television doctor of the past, nor the more recent competent but often fallible physicians in entertainment texts. Instead, his character is a fragmented text which privileges the biomedical over the personal or emotional with the ultimate goal of scientifically uncovering and resolving instances of disease. This article examines the implicit and explicit messages in House M.D. and critically analyzes both the show and its lead character in relation to the traditional medical drama genre that highlights the "doctor-hero" as the central character. While at first House seems to completely violate narrative and generic norms, ultimately the program provides a new form that reinforces the presence of the doctor-hero, but highlights House's character as the central figure who is personally and interpersonally problematic but biomedically effective.