Ätiologie und Pathogenese der Migräne

Migräne ist eine weltweit sehr häufige Erkrankung, die zu einer erheblichen Beeinträchtigung der Lebensqualität Betroffener führen kann. Bereits zu Beginn der Migräneattacke konnte eine Aktivierung des Hypothalamus gezeigt werden. Ein wesentlicher Aspekt ist dann die nachfolgende Aktivierung des trigeminovaskulären Systems. Hier spielt das Neuropeptid Calcitonin Gene-Related Peptide (CGRP) eine tragende Rolle. Durch die Aktivierung nozizeptiver Fasern kommt es zur Reizweiterleitung nach zentral in den Hirnstamm und über periphere und zentrale Sensibilisierung zu den typischen migräneartigen Kopfschmerzen. Durch besseres Verständnis der Pathophysiologie der Migräne ist es zuletzt gelungen, eine medikamentöse Prophylaxe zu entwickeln, die spezifisch in die komplexe Abfolge der Migränekaskade eingreift, indem das CGRP bzw. sein Rezeptor durch spezifische monoklonale Antikörper blockiert werden.     

List-method directed forgetting: The forget cue improves both encoding and retrieval of postcue information

In list-method directed forgetting, people are cued to forget a previously studied item list and to learn a new list instead. Such cuing typically leads to forgetting of the first list and to memory enhancement of the second, referred to as list 1 forgetting and list 2 enhancement. In the present study, two experiments are reported that examined influences of items' serial learning position in a list and the two lists' output order on list-method directed forgetting. The results show that list output order influences list 2 enhancement but not list 1 forgetting. The enhancement was higher when list 2 was recalled first than when list 1 was recalled first and, in both cases, was higher for early list 2 items than for middle and late list 2 items. In contrast, the forgetting was equally present for all list 1 items and did not depend on the two lists' output order. The findings suggest that two separate factors can contribute to list 2 enhancement: one (encoding) factor that is restricted to early list 2 items and does not depend on list output order, and another (retrieval) factor that pertains to all list 2 items and varies with the two lists' output order. A new two-mechanism account of directed forgetting is suggested that reconciles previous (encoding or retrieval) views on list 2 enhancement.     

Wenn Psychotherapie schadet …

Background

The examination of the negative and harmful effects of psychotherapy has recently moved into the focus of psychotherapy research. The investigation described in the following article specifically analyzes for the first time the contents of complaints by psychotherapy patients and presents a practical category system for classification of the negative effects of psychotherapeutic treatment.

Samples and method

A total of 67 cases of complaints submitted to the Ethics Association (reg. co). Ethics in Psychotherapy during the time period from 18.02.2008 to 27.12.2010 were analyzed with respect to the content in the sense of an inductive categorization and quantitative evaluation.

Results

From the available patient complaints a reliable category system could be elucidated. The violation of therapeutic base variables and violations of sexual limitations were the most common cause of complaints against male therapists whereas for female therapists accusations of violation of medical confidentiality and documentation duty were significantly higher.

Conclusions

The results of this study allow formulation of research recommendations for extended investigation of the negative effects of psychotherapy and reveal options for the development of a targeted risk management.     

Attention and spatial stimulus coding in the Simon task: a rejoinder to van der Lubbe and Abrahamse (2010)

Hommel (2011-this issue) has reviewed the major lines of research and ongoing controversies on and around the Simon effect. Van der Lubbe and Abrahamse (2010) take issue with Hommel's assessment of the role of attention shifting in the Simon effect. This rejoinder argues that van der Lubbe and Abrahamse's criticism is off target because it (a) fails to distinguish between the attention-shifting account of (spatial stimulus coding in) the Simon effect—which Hommel discusses and criticizes—and the premotor theory of attention—which Hommel does not discuss; (b) confuses the relationship between the attention-shifting account and the referential-coding account of spatial stimulus coding in the Simon effect—the actual topic of Hommel's discussion—with the relationship between the premotor theory and the theory of event coding—which the criticism focuses on; and (c) confuses the uncontroversial role of attention in stimulus selection with the controversial role of attention in the generation of location codes.     

The Simon effect as tool and heuristic

On its 43rd anniversary the Simon effect can look back at a long and varied history. First treated as a curious observation with implications for human factors research, it slowly evolved not only into a valuable target of psychological theorizing itself but also into a handy means to investigate attentional operations, the representation of space and of one's body, the cognitive representation of intentional action, and executive control. This article discusses the major characteristics of the Simon effect and the Simon task that laid the ground for this success and reviews the major lines of research, theoretical developments, and ongoing controversies on and around the Simon Effect and the cognitive processes it reflects.     

In Treatment

This article deals with current representations of psychotherapy in movies and television and focuses on the recent TV series In Treatment. It is discussed if and how this and other TV series might contribute to a change in the public image of psychotherapy. This discussion is based on studies investigating the public image of psychotherapy and its image within the media as well as the potential to use movies and TV as a stage for psychotherapeutic processes. Among several TV series dealing with psychotherapy, In Treatment plays a special role because of its conception as an intimate play. The series is described and discussed in relation to the question how realistic psychotherapy is staged and whether the hero of the series ??Dr. Paul Weston?? can be used as a model in psychotherapeutic training.