Serotonin Augmentation Reduces Response to Attack in Aggressive Individuals

ABSTRACT— We tested the theory that central serotonin (5-hydroxytryptamine, or 5-HT) activity regulates aggression by modulating response to provocation. Eighty men and women (40 with and 40 without a history of aggression) were randomly assigned to receive either 40 mg of paroxetine (to acutely augment serotonergic activity) or a placebo, administered using double-blind procedures. Aggression was assessed during a competitive reaction time game with a fictitious opponent. Shocks were selected by the participant and opponent before each trial, with the loser on each trial receiving the shock set by the other player. Provocation was manipulated by having the opponent select increasingly intense shocks for the participant and eventually an ostensibly severe shock toward the end of the trials. Aggression was measured by the number of severe shocks set by the participant for the opponent. As predicted, aggressive responding after provocation was attenuated by augmentation of serotonin in individuals with a pronounced history of aggression.     

Inpatient Standards of Care and the Suicidal Patient Part II: An Integration with Clinical Risk Management

The authors elaborate on the standards of care for the assessment, management, and treatment of hospitalized suicidal patients. The authors attempt to synthesize the concepts of the minimal standard of care with clinical risk management and clinical judgment. They point out the areas of overlap and where optimum care diverges from legal standards of care. Case examples are provided to illustrate major areas of concern. Alleged failures of omission and commission are discussed. Tables are provided that differentiate duties and responsibilities between and among clinicians, hospital staff, and hospital administration.     

Neurobiologic correlates of violence: relevance to criminal responsibility

Studies addressing the relationship between neurotransmitter functioning and violent crime are reviewed. A rich literature exists to support the notion that monoamine (i.e., serotonin, dopamine, and norepinephrine) neurotransmitter functioning is related to human aggressive behaviour. Results from these studies provide, at best, indirect evidence that neurotransmitter abnormalities are involved in violent criminal behavior. Few studies have specifically addressed the role of neurotransmitter functioning in violent crime. To illustrate how current knowledge in this area has been applied in forensic settings, a case study in which neurotransmitter functioning was introduced as evidence to support an insanity defense is presented. Potential problems associated with such defenses are discussed. © 1998 John Wiley & Sons, Ltd.     

Differing Perceptions of Mothers,Fathers, and children Concerning Children's Academic Performance

This study examined the hypothesis that mothers' views of their child's performance on an academic task are more synchronous with those of their child than are fathers' views. Parents of 30 sixth-grade children were asked to predict their child's memory spans on a recall and a recognition task given to each child. Parents and children were also asked to judge the importance for the child's performance on 10 attribution factors created for use with memory tests. In line with the hypothesis, mothers predicted the child's memory span more accurately than fathers, and the mothers' attributions were more congruent with those of their children. Mothers were also more aware than fathers of the different demands of the two memory tasks. These findings suggest that mothers may be more aware than fathers of their child's academic progress and that mothers' attitudes and expectations may be more influential in determining the child's path of development.     

The Kurt Cobain Suicide Crisis: Perspectives from Research,Public Health,and the News Media

The suicide of rock star Kurt Cobain in 1994 raised immediate concerns among suicidologists and the public at large about the potential for his death to spark copycat suicides, especially among vulnerable youth. The Seattle community, where Cobain lived and died, was especially affected by his sudden death. An overview of Cobain's life and death is presented and various crisis center and community-based interventions that occurred are discussed. Preliminary data collected from the Seattle Medical Examiner's Office and from the Seattle Crisis Center to assess the potential impact of Cobain's death on completed suicides and the incidence of suicide crisis calls are presented. The data obtained from the Seattle King County area suggest that the expected “Werther effect” apparently did not occur, but there was a significant increase in suicide crisis calls following his death. It is hypothesized that the lack of an apparent copycat effect in Seattle may be due to various aspects of the media coverage, the method used in Cobain's suicide, and the crisis center and community outreach interventions that occurred. The Cobain suicide and the role of media influence on copycat suicides are further discussed in commentaries from public health and news media perspectives.     

Dyadic Death: A Typology

In dyadic deaths, a second victim acts in consort with, is associated with, or is killed by a person who, contemporaneous with the first death, then suicides. Dyadic deaths thus include both homicide–suicides and suicide pacts. This paper describes, suggests organizing dynamics of, and illustrates distinct types of dyadic deaths. The proposed typology varies by levels of dominance, dependence–enmeshment, and the presence or absence of hostility in and between partners.