Science as a Vocation in the Era of Big Data: the Philosophy of Science behind Big Data and humanity’s Continued Part in Science

We now live in the era of big data, and according to its proponents, big data is poised to change science as we know it. Claims of having no theory and no ideology are made, and there is an assumption that the results of big data are trustworthy because it is considered free from human judgement, which is often considered inextricably linked with human error. These two claims lead to the idea that big data is the source of better scientific knowledge, through more objectivity, more data, and better analysis. In this paper I analyse the philosophy of science behind big data and make the claim that the death of many traditional sciences, and the human scientist, is much exaggerated. The philosophy of science of big data means that there are certain things big data does very well, and some things that it cannot do. I argue that humans will still be needed for mediating and creating theory, and for providing the legitimacy and values science needs as a normative social enterprise.     

Health-related quality of life in Parkinson's disease after pallidotomy and deep brain stimulation

This study explored the multidimensional outcome of three neurosurgical interventions for Parkinson's disease (PD): pallidotomy (N = 23), pallidal deep brain stimulation (DBS) (N = 9), and thalamic DBS (N = 7). All patients completed the Sickness Impact Profile (SIP) and the Beck Depression Inventory. Pallidotomy patients also completed the Profile of Mood States, the Beck Anxiety Inventory, and a disease-specific quality of life (QOL) measure, the Parkinson's Disease Questionnaire (PDQ-39). Three months after surgery, all neurosurgical groups showed significant improvements in mood and function, including physical, psychosocial, and overall functioning. Pallidal DBS and pallidotomy patients who completed additional QOL measures reported decreased anxiety and tension, increased vigor, improved mobility and ability to perform activities of daily living, and decreased perceived stigma. Psychosocial dysfunction scores from the SIP were related to depressed mood both at baseline (r = .42) and at followup (r = .45), but the physical dysfunction subscale was not related to mood at either time point, suggesting that disruption of social relationships due to PD may have more impact on affective distress than physical symptoms alone. Results suggest that neurosurgical interventions for PD improve disabling PD motor symptoms and also improve several domains of quality of life.     

Suicide attempts and family history of suicide in three psychiatric populations

The influence of a family history of suicide on suicide attempt rate and characteristics in depression, schizophrenia, and opioid dependence was examined. One hundred sixty inpatients with unipolar depression, 160 inpatients with schizophrenia, and 160 opioid-dependent patients were interviewed. Overall, a family history of suicide was associated with a higher risk for suicide attempt, with high-lethality method, with repeated attempts, and with number of attempts, while the interaction between family history and diagnostic group was not significant. Thus, a positive family history of suicide was a risk factor for several suicide attempt characteristics independent of psychiatric diagnosis.     

The Global Community, Religion, and Education: The Modernity of Dewey's Social Philosophy

As a starting point this paper takes Dewey's nowadays oftenstressed modernity and examines his social philosophy againstthe background of the current debates on republicanism andcommunitarianism. Particularly, the anaysis of Dewey's The Public and its Problem (1927) concludesthat the attention being paid to Dewey is problematic asspecific religious assumptions – explicitly developedin A Common Faith (1934) – lie in the backgroundof his social philosophy, and are hardly being recognized.However, as it shall be shown, without considering thereligious basis, neither Dewey's social philosophy norhis educational theory can be properly understood.     

Maternal postpartum depression is a risk factor for infant emotional variability at 4 months

Maternal postpartum depression (PPD) is a risk for disruption of mother–infant interaction. Infants of depressed mothers have been found to display less positive, more negative, and neutral affect. Other studies have found that infants of mothers with PPD inhibit both positive and negative affect. In a sample of 28 infants of mothers with PPD and 52 infants of nonclinical mothers, we examined the role of PPD diagnosis and symptoms for infants’ emotional variability, measured as facial expressions, vocal protest, and gaze using microanalysis, during a mother–infant face-to-face interaction. PPD symptoms and diagnosis were associated with (a) infants displaying fewer high negative, but more neutral/interest facial affect events, and (b) fewer gaze off events.  PPD diagnosis, but not symptoms, was associated with less infant vocal protest. Total duration of seconds of infant facial affective displays and gaze off was not related to PPD diagnosis or symptoms, suggesting that when infants of depressed mothers display high negative facial affect or gaze off, these expressions are more sustained, indicating lower infant ability to calm down and re-engage, interpreted as a disturbance in self-regulation. The findings highlight the importance of not only examining durations, but also frequencies, as the latter may inform infant emotional variability.     

儿童依“相似性”分类能力的发展及影响分类结果因素的实验研究

以4-9岁儿童为被试,用6张主要是相同事物的多少有差异的刺激图片为实验材料,采用全部呈现刺激图片和逐——呈现刺激图片,并且利用有无目标图的方法,来探讨儿童依“相似性”分类能力的发展及影响分类结果的因素。结果表明:(1)随着年龄的增长,儿童依“相似性”分类的能力在提高。(2)按目标图分类方式的分类结果显著好于自由分类方式的分类结果。(3)逐一呈现刺激方式的分类成绩显著好于全部呈现刺激方式的分类成绩。     

Questionnaire Assessment Potentially Overestimates Anxiety in Parkinson's Disease

Assessment of anxiety in Parkinson's disease (PD) is complicated by symptoms, such as trembling and shaking, that the two disorders have in common. This symptom overlap produces a potential for overestimation of the rate and severity of anxiety when assessed by self-report questionnaire. The purpose of this study is to estimate the extent to which anxiety scores in PD patients might be overestimated by two commonly-used mood state questionnaires. Fifty-nine patients with PD were administered the Beck Anxiety Inventory and the Profile of Mood States. Results indicate that the rate of clinically significant anxiety on these measures is indeed higher than the rate of clinical anxiety as determined by interview alone, suggesting the potential for overestimation of anxiety in PD when using self-report questionnaires.     

Validity and reliability of self-assessed physical fitness using visual analogue scales

To test the validity and reliability of self-assessed physical fitness samples included healthcare assistants working at a hospital (women=170, men=17), persons working with physically and mentally handicapped patients (women=530, men= 123), and two separate groups of healthcare students (a) women=91 and men=5 and (b) women=159 and men=10. Five components of physical fitness were self-assessed by Visual Analogue Scales with illustrations and verbal anchors for the extremes: aerobic fitness, muscle strength, endurance, flexibility, and balance. Convergent and divergent validity were evaluated by age-adjusted correlations stratified by sex with performance-based measures of physical fitness. Self-assessed aerobic fitness (r = .36 - .64) (women/men), muscle strength (r = .30 - .51), and flexibility (r = .36 - .31) showed moderate convergent validity. The divergent validity was satisfactory except for flexibility among men. The reliability was moderate to good (ICC = .62 - .80). Self-assessed aerobic fitness, muscle strength, and flexibility showed moderate construct validity and moderate to good reliability using visual analogues.     

农村重点高中学生学校人际关系状况的调查研究

采用《中学生师生关系测验问卷》和《中学生同学关系测验问卷》对随机选取的1120名苏北农村省级重点高中生进行测试。结果发现：绝大多数高中生的师生关系、同学关系是良好的和一般的,师生关系较差的只有6%左右,同学关系较差的却有20%左右;师生关系和同学关系都存在着显著的年级差异和性别差异。